PATENTS RELATED TO ANAEROBIC ORGANISMS

Although Dr. Demchick also represents patent seekers with non-microbiological inventions, his doctorate is in microbiology. Microbiology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving microbiology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of anaerobic organisms related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Amino acid sequences for therapeutic and prophylactic use against diseases due to clostridium difficile toxins (United States Patent 7,151,159)

Clostridium perfringens beta-2 toxin signal sequence, promoter and recombinant prokarote host cells comprising them (United States Patent 7,144,998)

Clostridial toxin derivatives and methods for treating pain (United States Patent 7,138,127)

Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics (United States Patent 7,090,973)

Method for purifying enzymes from clostridium histolyticum using multi-stage chromatography (United States Patent 7,083,964)

.alpha.-N-acetylgalactosaminidase from Clostridium perfringens (United States Patent 7,074,605)

Conjugates of galactose-binding lectins and clostridial neurotoxins as analgesics (United States Patent 7,052,702)

High throughput assays for the proteolytic activities of clostridial neurotoxins (United States Patent 7,034,107)

Biologically active, hemagglutinin from type A Clostridium botulinum and methods of use (United States Patent 6,994,859)

Neutralizing agent for clostridium bacterial neurotoxins and preparation method thereof (United States Patent 6,987,126)

Active immunization against clostridium difficile disease (United States Patent 6,969,520)

Clostridial toxin derivatives able to modify peripheral sensory afferent functions (United States Patent 6,962,703)

Leucine-based motif and clostridial neurotoxins (United States Patent 6,903,187)

Clostridial toxin therapy for Hashimoto's thyroiditis (United States Patent 6,821,520)

Isolation and purification of Clostridium botulinum toxins (United States Patent 6,818,409)

Water clarification treatment system through denitrification reduction by facultative anaerobic bacteria (United States Patent 6,818,123)

High throughput assays for the proteotytic activities of clostridial neurotoxins (United States Patent 6,762,280)

Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose (United States Patent 6,743,430)

Recombinant toxin A/toxin B vaccine against Clostridium difficile (United States Patent 6,733,760)

Method for determining effect of a clostridial toxin upon a muscle (United States Patent 6,688,311)

Passive immunization against clostridium difficile disease (United States Patent 6,680,168)

Amino acid sequences for therapeutic and prophylactic use against diseases due to Clostridium difficile toxins (United States Patent 6,667,035)

Clostridial toxin disease therapy (United States Patent 6,656,468)

Clostridial toxin derivatives and methods to treat pain (United States Patent 6,641,820)

Methods and compositions for prevention and treatment of Clostridium difficile-associated diseases (United States Patent 6,635,260)

Treating or preventing illness growth of Clostridium difficile (United States Patent 6,623,775)

Clostridium perfringens vaccine (United States Patent 6,610,300)

Substrate peptides and assays for detecting and measuring proteolytic activity of serotype A neurotoxin from clostridium botulinum (United States Patent 6,504,006)

Diagnostic tests and kits for Clostridium difficile (United States Patent 6,503,722)

Clostridial toxin derivatives and methods for treating pain (United States Patent 6,500,436)

Recombinant collagenase type I from clostridium histolyticum and its use for isolating cells and groups of cells (United States Patent 6,475,764)

Methods of use of quinolone compounds against anaerobic pathogenic bacteria (United States Patent 6,455,540)

Clostridium perfringens vaccines (United States Patent 6,403,094)

.alpha.-N-acetylgalactosaminidase from Clostridium perfringens (United States Patent 6,399,749)

Clostridial toxin derivatives able to modify peripheral sensory afferent functions (United States Patent 6,395,513)

Method of producing butanol using a mutant strain of Clostridium beijerinckii (United States Patent 6,358,717)

Methods of use of quinolone compounds against anaerobic pathogenic bacteria (United States Patent 6,331,550)

Probes for the diagnosis of infections caused by bacteroides fragilis (United States Patent 6,265,568)

Antimicrobial activity of hops extract against Clostridium botulinum, Clostridium difficile and Helicobacter pylori (United States Patent 6,251,461)

Host cells for expression of clostridial toxins and proteins (United States Patent 6,214,602)

Passive immunization against Clostridium difficile disease (United States Patent 6,214,341)

Modification of clostridial toxins for use as transport proteins (United States Patent 6,203,794)

Oxygen absorber for culturing anaerobic bacteria (United States Patent 6,153,422)

Biological production of ethanol from waste gases with Clostridium ljungdahlii (United States Patent 6,136,577)

Atmosphere regulator and method for culturing anaerobic bacteria (United States Patent 6,114,162)

Multicomponent clostridial vaccines using saponin adjuvants (United States Patent 6,083,512)

Clostridial toxin derivatives able to modify peripheral sensory afferent functions (United States Patent 5,989,545)

Assay for the proteolytic activity of serotype a from clostridium botulinum (United States Patent 5,965,699)

Diagnostic tests and kits for Clostridium difficile (United States Patent 5,965,375)

Expression system for clostridium species (United States Patent 5,955,368)

Vaccine for clostridium botulinum neurotoxin (United States Patent 5,919,665)

Clostridium difficle toxins as mucosal adjuvants (United States Patent 5,919,463)

Inhibition of clostridia with lactic acid bacteria (United States Patent 5,908,646)

Primers for the amplification of genes coding for the enterotoxin and the lecithinase of Clostridium perfringens and their application to the detection and numeration of these bacteriae (United States Patent 5,874,220)

Recombinant proteinase from clostridium histolyticum and its use for isolating cells and groups of cells (United States Patent 5,853,976)

DNA encoding clostridium perfringens alpha-toxin peptides (United States Patent 5,851,827)

Chemically-modified clostridiatoxin with improved properties (United States Patent 5,837,265)

Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease (United States Patent 5,830,741)

Clostridium bifermentans DNA fragment bearing genes coding for proteins linked to an insecticidal activity (United States Patent 5,830,722)

Clostridium perfringens vaccines (United States Patent 5,817,317)

Recombinant clostridial toxin protein (United States Patent 5,814,477)

Biological production of acetic acid from waste gases with Clostridium ljungdahlii (United States Patent 5,807,722)

DNA Sequences and amino acid sequences of class B beta-lactamase enzymes from bacteroides fragilis (United States Patent 5,792,642)

Detection of periodontal pathogens including bacteroides forsythus, porphyromonas gingivalis, prevotilla intermedia and prevotella nigrescens (United States Patent 5,789,174)

Therapeutic treatment of clostridium difficile associated diseases (United States Patent 5,773,000)

Clostridium difficile toxin disease therapy (United States Patent 5,762,934)

Secretion of clostridium cellulase by E. coli (United States Patent 5,759,845)

Continuous two stage, dual path anaerobic fermentation of butanol and other organic solvents using two different strains of bacteria (United States Patent 5,753,474)

Treatment of Clostridium difficile induced disease (United States Patent 5,736,139)

Clostridial toxin disease therapy (United States Patent 5,719,267)

Methods for screening class B beta-lactamase enzymes from Bacteroides fragilis (United States Patent 5,705,340)

Clostridium perfingens type a enterotoxin toxoid and methods of preparation and use as a vaccine and therapeutic agent (United States Patent 5,695,956)

Cloning and identification of a two component signal transducing regulatory system from bacteroides fragilis (United States Patent 5,679,540)

Determination of the toxicity of water using an anaerobic bacterial culture (United States Patent 5,674,702)

Production of monoclonal antibodies to bacteroides gingivalis by hybridoma BGII, VF9/2D (United States Patent 5,665,559)

Two phase anaerobic digestion process utilizing thermophilic, fixed growth bacteria (United States Patent 5,630,942)

Method of purification of clostridium difficile toxin A and production of mono-specific antibodies (United States Patent 5,610,023)

Cloning and identification of a two component signal transducing regulatory system from Bacteroides fragilis (United States Patent 5,606,022)

Avian antitoxins to clostridium difficle toxin A (United States Patent 5,601,823)

Therapy for clostridial botulinum toxin (United States Patent 5,599,539)

Clostridium stain which produces acetic acid from waste gases (United States Patent 5,593,886)

DNA sequences and amino acid sequences of class B beta lactamase enzymes from bacteroides fragilis (United States Patent 5,571,693)

Primers for the amplification of genes coding for the enterotoxin and the lecithinase of Clostridium perfringens and their application to the determination of the presence and numeration of these bacteriae (United States Patent 5,538,851)

Secretion of Clostridium cellulase by E. coli (United States Patent 5,496,725)

Therapeutic use of clostridium difficile toxin A (United States Patent 5,466,672)

Anthra[1,9-c,d]pyrazol-6-(2H)-ones useful for treating anaerobic bacterial infections (United States Patent 5,447,950)

Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli (United States Patent 5,443,826)

Method of treating clostridium difficile colitis and cholera (United States Patent 5,436,239)

Recombinant 68,000 dalton collagenase of Clostridium histolyticum (United States Patent 5,418,157)

Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds using 10-formyltetrahydrofolate synthetase from clostridium (United States Patent 5,334,535)

Method for growth promotion of animals and powder compositions containing killed microbial cells of bacteria belonging to genus clostridium (United States Patent 5,292,523)

Composite for Clostridium difficile diarrhea and pseudomembranous colitis (United States Patent 5,266,315)

Mutant of bacterium Clostridium histolyticum, a process for the obtaining thereof, and its use in the production of clostripain-free collagenase (United States Patent 5,252,481)

Monoclonal antibodies specific for Toxin B of Clostridium difficile (United States Patent 5,231,003)

Degeneration-resistant solventogenic clostridia (United States Patent 5,210,032)

Plaque-inhibiting protein from bacteroides loeschei and methods for using the same (United States Patent 5,202,113)

Molecular cloning of the genes responsible for collagenase production from Clostridium histolyticum (United States Patent 5,177,017)

Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism (United States Patent 5,173,429)

Process for massive conversion of clostridia in synchronized cells of elongated length or refractile endospores (United States Patent 5,158,887)

Detection, isolation and purification of Clostridium difficile toxin A with toxin receptors (United States Patent 5,098,826)

Amino acid sequences for therapeutic and prophylactic use against diseases due to clostridium difficile toxins (United States Patent 7,151,159)

Clostridium perfringens beta-2 toxin signal sequence, promoter and recombinant prokarote host cells comprising them (United States Patent 7,144,998)

Clostridial toxin derivatives and methods for treating pain (United States Patent 7,138,127)

Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics (United States Patent 7,090,973)

Method for purifying enzymes from clostridium histolyticum using multi-stage chromatography (United States Patent 7,083,964)

.alpha.-N-acetylgalactosaminidase from Clostridium perfringens (United States Patent 7,074,605)

Conjugates of galactose-binding lectins and clostridial neurotoxins as analgesics (United States Patent 7,052,702)

High throughput assays for the proteolytic activities of clostridial neurotoxins (United States Patent 7,034,107)

Biologically active, hemagglutinin from type A Clostridium botulinum and methods of use (United States Patent 6,994,859)

Neutralizing agent for clostridium bacterial neurotoxins and preparation method thereof (United States Patent 6,987,126)

Active immunization against clostridium difficile disease (United States Patent 6,969,520)

Clostridial toxin derivatives able to modify peripheral sensory afferent functions (United States Patent 6,962,703)

Leucine-based motif and clostridial neurotoxins (United States Patent 6,903,187)

Clostridial toxin therapy for Hashimoto's thyroiditis (United States Patent 6,821,520)

Isolation and purification of Clostridium botulinum toxins (United States Patent 6,818,409)

Water clarification treatment system through denitrification reduction by facultative anaerobic bacteria (United States Patent 6,818,123)

High throughput assays for the proteotytic activities of clostridial neurotoxins (United States Patent 6,762,280)

Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose (United States Patent 6,743,430)

Recombinant toxin A/toxin B vaccine against Clostridium difficile (United States Patent 6,733,760)

Method for determining effect of a clostridial toxin upon a muscle (United States Patent 6,688,311)

Passive immunization against clostridium difficile disease (United States Patent 6,680,168)

Amino acid sequences for therapeutic and prophylactic use against diseases due to Clostridium difficile toxins (United States Patent 6,667,035)

Clostridial toxin disease therapy (United States Patent 6,656,468)

Clostridial toxin derivatives and methods to treat pain (United States Patent 6,641,820)

Methods and compositions for prevention and treatment of Clostridium difficile-associated diseases (United States Patent 6,635,260)

Treating or preventing illness growth of Clostridium difficile (United States Patent 6,623,775)

Clostridium perfringens vaccine (United States Patent 6,610,300)

Substrate peptides and assays for detecting and measuring proteolytic activity of serotype A neurotoxin from clostridium botulinum (United States Patent 6,504,006)

Diagnostic tests and kits for Clostridium difficile (United States Patent 6,503,722)

Clostridial toxin derivatives and methods for treating pain (United States Patent 6,500,436)

Recombinant collagenase type I from clostridium histolyticum and its use for isolating cells and groups of cells (United States Patent 6,475,764)

Methods of use of quinolone compounds against anaerobic pathogenic bacteria (United States Patent 6,455,540)

Clostridium perfringens vaccines (United States Patent 6,403,094)

.alpha.-N-acetylgalactosaminidase from Clostridium perfringens (United States Patent 6,399,749)

Clostridial toxin derivatives able to modify peripheral sensory afferent functions (United States Patent 6,395,513)

Method of producing butanol using a mutant strain of Clostridium beijerinckii (United States Patent 6,358,717)

Methods of use of quinolone compounds against anaerobic pathogenic bacteria (United States Patent 6,331,550)

Probes for the diagnosis of infections caused by bacteroides fragilis (United States Patent 6,265,568)

Antimicrobial activity of hops extract against Clostridium botulinum, Clostridium difficile and Helicobacter pylori (United States Patent 6,251,461)

Host cells for expression of clostridial toxins and proteins (United States Patent 6,214,602)

Passive immunization against Clostridium difficile disease (United States Patent 6,214,341)

Modification of clostridial toxins for use as transport proteins (United States Patent 6,203,794)

Oxygen absorber for culturing anaerobic bacteria (United States Patent 6,153,422)

Biological production of ethanol from waste gases with Clostridium ljungdahlii (United States Patent 6,136,577)

Atmosphere regulator and method for culturing anaerobic bacteria (United States Patent 6,114,162)

Multicomponent clostridial vaccines using saponin adjuvants (United States Patent 6,083,512)

Clostridial toxin derivatives able to modify peripheral sensory afferent functions (United States Patent 5,989,545)

Assay for the proteolytic activity of serotype a from clostridium botulinum (United States Patent 5,965,699)

Diagnostic tests and kits for Clostridium difficile (United States Patent 5,965,375)

Expression system for clostridium species (United States Patent 5,955,368)

Vaccine for clostridium botulinum neurotoxin (United States Patent 5,919,665)

Clostridium difficle toxins as mucosal adjuvants (United States Patent 5,919,463)

Inhibition of clostridia with lactic acid bacteria (United States Patent 5,908,646)

Primers for the amplification of genes coding for the enterotoxin and the lecithinase of Clostridium perfringens and their application to the detection and numeration of these bacteriae (United States Patent 5,874,220)

Recombinant proteinase from clostridium histolyticum and its use for isolating cells and groups of cells (United States Patent 5,853,976)

DNA encoding clostridium perfringens alpha-toxin peptides (United States Patent 5,851,827)

Chemically-modified clostridiatoxin with improved properties (United States Patent 5,837,265)

Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease (United States Patent 5,830,741)

Clostridium bifermentans DNA fragment bearing genes coding for proteins linked to an insecticidal activity (United States Patent 5,830,722)

Clostridium perfringens vaccines (United States Patent 5,817,317)

Recombinant clostridial toxin protein (United States Patent 5,814,477)

Biological production of acetic acid from waste gases with Clostridium ljungdahlii (United States Patent 5,807,722)

DNA Sequences and amino acid sequences of class B beta-lactamase enzymes from bacteroides fragilis (United States Patent 5,792,642)

Detection of periodontal pathogens including bacteroides forsythus, porphyromonas gingivalis, prevotilla intermedia and prevotella nigrescens (United States Patent 5,789,174)

Therapeutic treatment of clostridium difficile associated diseases (United States Patent 5,773,000)

Clostridium difficile toxin disease therapy (United States Patent 5,762,934)

Secretion of clostridium cellulase by E. coli (United States Patent 5,759,845)

Continuous two stage, dual path anaerobic fermentation of butanol and other organic solvents using two different strains of bacteria (United States Patent 5,753,474)

Treatment of Clostridium difficile induced disease (United States Patent 5,736,139)

Clostridial toxin disease therapy (United States Patent 5,719,267)

Methods for screening class B beta-lactamase enzymes from Bacteroides fragilis (United States Patent 5,705,340)

Clostridium perfingens type a enterotoxin toxoid and methods of preparation and use as a vaccine and therapeutic agent (United States Patent 5,695,956)

Cloning and identification of a two component signal transducing regulatory system from bacteroides fragilis (United States Patent 5,679,540)

Determination of the toxicity of water using an anaerobic bacterial culture (United States Patent 5,674,702)

Production of monoclonal antibodies to bacteroides gingivalis by hybridoma BGII, VF9/2D (United States Patent 5,665,559)

Two phase anaerobic digestion process utilizing thermophilic, fixed growth bacteria (United States Patent 5,630,942)

Method of purification of clostridium difficile toxin A and production of mono-specific antibodies (United States Patent 5,610,023)

Cloning and identification of a two component signal transducing regulatory system from Bacteroides fragilis (United States Patent 5,606,022)

Avian antitoxins to clostridium difficle toxin A (United States Patent 5,601,823)

Therapy for clostridial botulinum toxin (United States Patent 5,599,539)

Clostridium stain which produces acetic acid from waste gases (United States Patent 5,593,886)

DNA sequences and amino acid sequences of class B beta lactamase enzymes from bacteroides fragilis (United States Patent 5,571,693)

Primers for the amplification of genes coding for the enterotoxin and the lecithinase of Clostridium perfringens and their application to the determination of the presence and numeration of these bacteriae (United States Patent 5,538,851)

Secretion of Clostridium cellulase by E. coli (United States Patent 5,496,725)

Therapeutic use of clostridium difficile toxin A (United States Patent 5,466,672)

Anthra[1,9-c,d]pyrazol-6-(2H)-ones useful for treating anaerobic bacterial infections (United States Patent 5,447,950)

Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli (United States Patent 5,443,826)

Method of treating clostridium difficile colitis and cholera (United States Patent 5,436,239)

Recombinant 68,000 dalton collagenase of Clostridium histolyticum (United States Patent 5,418,157)

Process for the preparation of optically pure diastereoisomers of tetrahydrofolate compounds using 10-formyltetrahydrofolate synthetase from clostridium (United States Patent 5,334,535)

Method for growth promotion of animals and powder compositions containing killed microbial cells of bacteria belonging to genus clostridium (United States Patent 5,292,523)

Composite for Clostridium difficile diarrhea and pseudomembranous colitis (United States Patent 5,266,315)

Mutant of bacterium Clostridium histolyticum, a process for the obtaining thereof, and its use in the production of clostripain-free collagenase (United States Patent 5,252,481)

Monoclonal antibodies specific for Toxin B of Clostridium difficile (United States Patent 5,231,003)

Degeneration-resistant solventogenic clostridia (United States Patent 5,210,032)

Plaque-inhibiting protein from bacteroides loeschei and methods for using the same (United States Patent 5,202,113)

Molecular cloning of the genes responsible for collagenase production from Clostridium histolyticum (United States Patent 5,177,017)

Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism (United States Patent 5,173,429)

Process for massive conversion of clostridia in synchronized cells of elongated length or refractile endospores (United States Patent 5,158,887)

Detection, isolation and purification of Clostridium difficile toxin A with toxin receptors (United States Patent 5,098,826)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.