PATENTS RELATED TO ANTIBODIES

Professor Demchick's Patent Services

Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)

PATENTS RELATED TO ANTIBODIES

Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.
If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.
The following sampling is to give you some sense of the types of antibodies related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.
It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Antibodies that bind PRO4994 polypeptides (United States Patent 7,153,941)
PRO354 antibodies (United States Patent 7,153,939)
Stabilization of antibodies or fragments thereof (United States Patent 7,153,819)
Artificial antibody polypeptides (United States Patent 7,153,661)
Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope (United States Patent 7,153,509)
Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4 (United States Patent 7,153,508)
Human antibodies specific for interleukin 15 (IL-15) (United States Patent 7,153,507)
Use of anti-ferritin monoclonal antibodies in the treatment of some cancers (United States Patent 7,153,506)
Antibody to mammalian cytokine-like polypeptide-10 (United States Patent 7,151,166)
Antibodies immunospecific for a novel human G-protein coupled receptor family (United States Patent 7,151,165)
Anti-CD20 antibodies and fusion proteins thereof and methods of use (United States Patent 7,151,164)
High affinity monoclonal antibody for recognizing the estrogen receptor (ER) and method for creating the antibody (United States Patent 7,148,332)
Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)
Expression technology for proteins containing a hybrid isotype antibody moiety (United States Patent 7,148,321)
Mitochondrial creatine kinase antibody (United States Patent 7,148,063)
Method of rapid production of hybridomas expressing monoclonal antibodies on the cell surface (United States Patent 7,148,040)
Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof (United States Patent 7,148,038)
Methods to improve immunogenicity of antigens and specificity of antibodies (United States Patent 7,147,858)
Topical treatment of psoriasis using neutralizing antibodies to interleukin-8 (United States Patent 7,147,854)
Anti-pro211 polypeptide antibodies (United States Patent 7,147,853)
Production of antibodies using cre-mediated site-specific recombination (United States Patent 7,145,056)
Antibody to a polypeptide overexpressed in tumors (United States Patent 7,144,990)
SCF antibody compositions and methods of using the same (United States Patent 7,144,731)
Synthetic antigen for the detection of antibodies immunoreactive with HIV virus (United States Patent 7,144,697)
Human monoclonal antibodies to interleukin-5 (United States Patent 7,141,653)
Antibodies to PRO1561 polypeptide (United States Patent 7,141,652)
Monoclonal antibodies against human apoptosis inhibitory protein NAIP and method for assaying the NAIP (United States Patent 7,141,435)
Antibodies to the propeptide of Candida albicans and methods of use (United States Patent 7,138,502)
Antibodies that immunospecifically bind BLyS (United States Patent 7,138,501)
Antibodies to human 4-1BB (United States Patent 7,138,500)
Antibodies to MCP-4 (United States Patent 7,138,498)
Human monoclonal antibodies against human CXCR4 (United States Patent 7,138,496)
Hybridoma, an antibody resistant to an interfering substance, and a kit for immunological analysis (United States Patent 7,138,241)
Methods of treating rheumatoid arthritis with anti-TNF antibodies (United States Patent 7,138,118)
Anti-CCR4 antibodies and methods of use therefor (United States Patent 7,138,117)
Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody (United States Patent 7,138,116)
Use of bi-specific antibodies for pre-targeting diagnosis and therapy (United States Patent 7,138,103)
Interferon-.gamma. inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use (United States Patent 7,135,458)
Tetrameric antibody complexes for blocking non-specific labeling of antigens (United States Patent 7,135,340)
Human antibodies (United States Patent 7,135,287)
Methods for treating sarcoidosis using anti-TNF antibodies and fragments thereof (United States Patent 7,135,179)
Methods of treating disseminated intravascular coagulation using anti-TNF antibodies (United States Patent 7,135,178)
Antibodies directed to PDGFD and uses thereof (United States Patent 7,135,174)
Modified anti-EGFR antibodies with reduced immunogenicity (United States Patent 7,132,511)
Specific human antibodies for selective cancer therapy (United States Patent 7,132,510)
Methods and host cells for producing human monoclonal antibodies to CTLA-4 (United States Patent 7,132,281)
Stabilized liquid anti-RSV antibody formulations (United States Patent 7,132,100)
Methods of modulating T lymphocyte costimulation with an antibody to an 8F4 polypeptide (United States Patent 7,132,099)
Multivalent antibody constructs (United States Patent 7,129,330)
Production of humanized antibodies in transgenic animals (United States Patent 7,129,084)
Antibodies to a growth/differentiation factor of the TGF-.beta. family (United States Patent 7,129,054)
Methods for treating systemic lupus erythematosus using anti-TNF antibodies and fragments thereof (United States Patent 7,128,908)
Methods of treating crohn's disease with anti-TNF antibodies (United States Patent 7,128,907)
Anti-Pro268 antibodies (United States Patent 7,125,962)
Methods for detection of disease-associated antibodies in urine (United States Patent 7,125,681)
Methods for treatment of asthmatic disorders using a monoclonal antibody to 8F4 polypeptide (United States Patent 7,125,551)
Vascular endothelial growth factor D (VEGF-D) antibodies and vectors, and methods of use (United States Patent 7,122,654)
Chemokine alpha-2 antibodies (United States Patent 7,122,639)
Monoclonal human natural antibodies (United States Patent 7,122,638)
Antibody fragment-polymer conjugates and uses of same (United States Patent 7,122,636)
Pharmaceutical compositions containing antigen-antibody complexes and uses therefor (United States Patent 7,122,380)
Amyloid beta-protein 3(pE)-42 antibodies and uses thereof (United States Patent 7,122,374)
Retro peptides, antibodies thereto and their uses for vaccination and in vitro diagnosis (United States Patent 7,122,193)
Antibodies which bind with proteins of human immunodeficiency virus type 1 (HIV-1), and immune complexes comprising proteins of HIV-1 (United States Patent 7,122,188)
Treating autoimmune diseases with humanized anti-CD40L antibody (United States Patent 7,122,187)
Anti-CCR5 antibody (United States Patent 7,122,185)
Specific monoclonal antibody against terbinafine (United States Patent 7,122,184)
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof (United States Patent 7,119,248)
Antibodies specific to human prostacyclin synthase (United States Patent 7,119,176)
Antibody to mammalian cytokine-like polypeptide-10 (United States Patent 7,119,175)
Method for producing human antibodies in SCID mice which uses dendritic cells pulsed with antigen-antibody complexes and antigen-antibody complexes as immunizing agents (United States Patent 7,118,924)
Antibodies to vertebrate delta proteins and fragments (United States Patent 7,118,890)
Engineering antibodies that bind irreversibly (United States Patent 7,118,745)
Structure-based selection and affinity maturation of antibody library (United States Patent 7,117,096)
Humanized antibody specific for surface antigen pre-S1 of HBV and preparation method thereof (United States Patent 7,115,723)
Haptens, immunogens, antibodies and conjugates to 2-oxo-3-hydroxy-LSD (United States Patent 7,115,718)
Anti-TRAIL-R antibodies (United States Patent 7,115,717)
Tumor specific monoclonal antibodies (United States Patent 7,115,716)
Anti-idiotype antibodies to MN proteins and MN polypeptides (United States Patent 7,115,715)
Protein scaffolds for antibody mimics and other binding proteins (United States Patent 7,115,396)
Anti-mammalian CX3C cytokine antibodies (United States Patent 7,115,379)
Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections (United States Patent 7,115,264)
Variable region of the monoclonal antibody against the HBV S-surface antigen and a gene encoding the same (United States Patent 7,112,664)
Anti-metasin antibodies and their methods of use (United States Patent 7,112,662)
Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha (United States Patent 7,112,661)
Dual expression vector system for antibody expression in bacterial and mammalian cells (United States Patent 7,112,439)
Antibodies to calcium independent cytosolic phospholipase A.sub.2/B enzymes (United States Patent 7,112,325)
Nucleic acid molecules encoding human tumor necrosis factor .alpha.-specific antibodies (United States Patent 7,109,320)
Antibodies to human vascular endothelial growth factor 2 (United States Patent 7,109,308)
Antibodies to human oncogene induced secreted protein I (United States Patent 7,109,306)
Humanized anti-CD19 antibodies (United States Patent 7,109,304)
Antibodies that specifically bind to GMAD (United States Patent 7,109,302)
Compounds capable of modulating the activity and stimulating the production of a catalytic antibody (United States Patent 7,109,291)
Methods for expressing and recovering human monoclonal antibodies to CTLA-4 (United States Patent 7,109,003)
Methods of treating inflammation using antibodies to M-CSF (United States Patent 7,108,852)
Secreted protein HHTLF25 antibodies (United States Patent 7,105,644)
Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates (United States Patent 7,105,643)
Monoclonal antibodies specific for phosphorylated estrogen receptor alpha (Ser118) and uses thereof (United States Patent 7,105,642)
MCP-1 receptor antibodies (United States Patent 7,105,641)
Antibodies that bind PRO4994 polypeptides (United States Patent 7,153,941)
PRO354 antibodies (United States Patent 7,153,939)
Stabilization of antibodies or fragments thereof (United States Patent 7,153,819)
Artificial antibody polypeptides (United States Patent 7,153,661)
Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope (United States Patent 7,153,509)
Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4 (United States Patent 7,153,508)
Human antibodies specific for interleukin 15 (IL-15) (United States Patent 7,153,507)
Use of anti-ferritin monoclonal antibodies in the treatment of some cancers (United States Patent 7,153,506)
Antibody to mammalian cytokine-like polypeptide-10 (United States Patent 7,151,166)
Antibodies immunospecific for a novel human G-protein coupled receptor family (United States Patent 7,151,165)
Anti-CD20 antibodies and fusion proteins thereof and methods of use (United States Patent 7,151,164)
High affinity monoclonal antibody for recognizing the estrogen receptor (ER) and method for creating the antibody (United States Patent 7,148,332)
Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)
Expression technology for proteins containing a hybrid isotype antibody moiety (United States Patent 7,148,321)
Mitochondrial creatine kinase antibody (United States Patent 7,148,063)
Method of rapid production of hybridomas expressing monoclonal antibodies on the cell surface (United States Patent 7,148,040)
Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof (United States Patent 7,148,038)
Methods to improve immunogenicity of antigens and specificity of antibodies (United States Patent 7,147,858)
Topical treatment of psoriasis using neutralizing antibodies to interleukin-8 (United States Patent 7,147,854)
Anti-pro211 polypeptide antibodies (United States Patent 7,147,853)
Production of antibodies using cre-mediated site-specific recombination (United States Patent 7,145,056)
Antibody to a polypeptide overexpressed in tumors (United States Patent 7,144,990)
SCF antibody compositions and methods of using the same (United States Patent 7,144,731)
Synthetic antigen for the detection of antibodies immunoreactive with HIV virus (United States Patent 7,144,697)
Human monoclonal antibodies to interleukin-5 (United States Patent 7,141,653)
Antibodies to PRO1561 polypeptide (United States Patent 7,141,652)
Monoclonal antibodies against human apoptosis inhibitory protein NAIP and method for assaying the NAIP (United States Patent 7,141,435)
Antibodies to the propeptide of Candida albicans and methods of use (United States Patent 7,138,502)
Antibodies that immunospecifically bind BLyS (United States Patent 7,138,501)
Antibodies to human 4-1BB (United States Patent 7,138,500)
Antibodies to MCP-4 (United States Patent 7,138,498)
Human monoclonal antibodies against human CXCR4 (United States Patent 7,138,496)
Hybridoma, an antibody resistant to an interfering substance, and a kit for immunological analysis (United States Patent 7,138,241)
Methods of treating rheumatoid arthritis with anti-TNF antibodies (United States Patent 7,138,118)
Anti-CCR4 antibodies and methods of use therefor (United States Patent 7,138,117)
Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody (United States Patent 7,138,116)
Use of bi-specific antibodies for pre-targeting diagnosis and therapy (United States Patent 7,138,103)
Interferon-.gamma. inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use (United States Patent 7,135,458)
Tetrameric antibody complexes for blocking non-specific labeling of antigens (United States Patent 7,135,340)
Human antibodies (United States Patent 7,135,287)
Methods for treating sarcoidosis using anti-TNF antibodies and fragments thereof (United States Patent 7,135,179)
Methods of treating disseminated intravascular coagulation using anti-TNF antibodies (United States Patent 7,135,178)
Antibodies directed to PDGFD and uses thereof (United States Patent 7,135,174)
Modified anti-EGFR antibodies with reduced immunogenicity (United States Patent 7,132,511)
Specific human antibodies for selective cancer therapy (United States Patent 7,132,510)
Methods and host cells for producing human monoclonal antibodies to CTLA-4 (United States Patent 7,132,281)
Stabilized liquid anti-RSV antibody formulations (United States Patent 7,132,100)
Methods of modulating T lymphocyte costimulation with an antibody to an 8F4 polypeptide (United States Patent 7,132,099)
Multivalent antibody constructs (United States Patent 7,129,330)
Production of humanized antibodies in transgenic animals (United States Patent 7,129,084)
Antibodies to a growth/differentiation factor of the TGF-.beta. family (United States Patent 7,129,054)
Methods for treating systemic lupus erythematosus using anti-TNF antibodies and fragments thereof (United States Patent 7,128,908)
Methods of treating crohn's disease with anti-TNF antibodies (United States Patent 7,128,907)
Anti-Pro268 antibodies (United States Patent 7,125,962)
Methods for detection of disease-associated antibodies in urine (United States Patent 7,125,681)
Methods for treatment of asthmatic disorders using a monoclonal antibody to 8F4 polypeptide (United States Patent 7,125,551)
Vascular endothelial growth factor D (VEGF-D) antibodies and vectors, and methods of use (United States Patent 7,122,654)
Chemokine alpha-2 antibodies (United States Patent 7,122,639)
Monoclonal human natural antibodies (United States Patent 7,122,638)
Antibody fragment-polymer conjugates and uses of same (United States Patent 7,122,636)
Pharmaceutical compositions containing antigen-antibody complexes and uses therefor (United States Patent 7,122,380)
Amyloid beta-protein 3(pE)-42 antibodies and uses thereof (United States Patent 7,122,374)
Retro peptides, antibodies thereto and their uses for vaccination and in vitro diagnosis (United States Patent 7,122,193)
Antibodies which bind with proteins of human immunodeficiency virus type 1 (HIV-1), and immune complexes comprising proteins of HIV-1 (United States Patent 7,122,188)
Treating autoimmune diseases with humanized anti-CD40L antibody (United States Patent 7,122,187)
Anti-CCR5 antibody (United States Patent 7,122,185)
Specific monoclonal antibody against terbinafine (United States Patent 7,122,184)
Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof (United States Patent 7,119,248)
Antibodies specific to human prostacyclin synthase (United States Patent 7,119,176)
Antibody to mammalian cytokine-like polypeptide-10 (United States Patent 7,119,175)
Method for producing human antibodies in SCID mice which uses dendritic cells pulsed with antigen-antibody complexes and antigen-antibody complexes as immunizing agents (United States Patent 7,118,924)
Antibodies to vertebrate delta proteins and fragments (United States Patent 7,118,890)
Engineering antibodies that bind irreversibly (United States Patent 7,118,745)
Structure-based selection and affinity maturation of antibody library (United States Patent 7,117,096)
Humanized antibody specific for surface antigen pre-S1 of HBV and preparation method thereof (United States Patent 7,115,723)
Haptens, immunogens, antibodies and conjugates to 2-oxo-3-hydroxy-LSD (United States Patent 7,115,718)
Anti-TRAIL-R antibodies (United States Patent 7,115,717)
Tumor specific monoclonal antibodies (United States Patent 7,115,716)
Anti-idiotype antibodies to MN proteins and MN polypeptides (United States Patent 7,115,715)
Protein scaffolds for antibody mimics and other binding proteins (United States Patent 7,115,396)
Anti-mammalian CX3C cytokine antibodies (United States Patent 7,115,379)
Monoclonal antibodies to the fibronectin binding protein and method of use in treating or preventing infections (United States Patent 7,115,264)
Variable region of the monoclonal antibody against the HBV S-surface antigen and a gene encoding the same (United States Patent 7,112,664)
Anti-metasin antibodies and their methods of use (United States Patent 7,112,662)
Variable heavy chain and variable light chain regions of antibodies to human platelet glycoprotein Ib alpha (United States Patent 7,112,661)
Dual expression vector system for antibody expression in bacterial and mammalian cells (United States Patent 7,112,439)
Antibodies to calcium independent cytosolic phospholipase A.sub.2/B enzymes (United States Patent 7,112,325)
Nucleic acid molecules encoding human tumor necrosis factor .alpha.-specific antibodies (United States Patent 7,109,320)
Antibodies to human vascular endothelial growth factor 2 (United States Patent 7,109,308)
Antibodies to human oncogene induced secreted protein I (United States Patent 7,109,306)
Humanized anti-CD19 antibodies (United States Patent 7,109,304)
Antibodies that specifically bind to GMAD (United States Patent 7,109,302)
Compounds capable of modulating the activity and stimulating the production of a catalytic antibody (United States Patent 7,109,291)
Methods for expressing and recovering human monoclonal antibodies to CTLA-4 (United States Patent 7,109,003)
Methods of treating inflammation using antibodies to M-CSF (United States Patent 7,108,852)
Secreted protein HHTLF25 antibodies (United States Patent 7,105,644)
Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates (United States Patent 7,105,643)
Monoclonal antibodies specific for phosphorylated estrogen receptor alpha (Ser118) and uses thereof (United States Patent 7,105,642)
MCP-1 receptor antibodies (United States Patent 7,105,641)
Antibodies that bind PRO4994 polypeptides (United States Patent 7,153,941)
PRO354 antibodies (United States Patent 7,153,939)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.