PATENTS RELATED TO BIOLUMINESCENCE

Professor Demchick's Patent Services

Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)

PATENTS RELATED TO BIOLUMINESCENCE

Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.
If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.
The following sampling is to give you some sense of the types of bioluminescence related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.
It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Bioluminescent protease assay (United States Patent 7,148,030)
Bioluminescence regenerative cycle (BRC) for nucleic acid quantification (United States Patent 7,141,370)
Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen (United States Patent 7,090,992)
Transgenic bioluminescent plants (United States Patent 7,049,483)
Sample collection and bioluminescent sample testing system (United States Patent 7,030,403)
Bioluminescent assays and bacterial strains useful therein (United States Patent 6,956,113)
Chimeric GFP-aequorin as bioluminescent Ca++reporters at the single cell level (United States Patent 6,936,475)
Methods and apparatus to improve the sensitivity and reproducibility of bioluminescent analytical methods (United States Patent 6,927,851)
Bioluminescent bioreporter integrated circuit detection methods (United States Patent 6,905,834)
Chimeric GFP-aequorin as bioluminescent Ca++ reporters at the single cell level (United States Patent 6,800,492)
Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses (United States Patent 6,689,391)
Bioluminescent biosensor device (United States Patent 6,544,729)
Method of making bioluminescent assay reagent based on non-viable E. coli (United States Patent 6,524,810)
Luminescent tool, its auxiliary member and method of preserving bioluminescent composition used in the tool and the auxiliary member (United States Patent 6,521,304)
Modified bioluminescent proteins and their use (United States Patent 6,492,500)
Method for rapidly detecting and enumerating microorganisms in mammalian cell preparations using ATP bioluminescence (United States Patent 6,465,201)
Modified bioluminescent proteins and their use (United States Patent 6,440,665)
Bioluminescent novelty items (United States Patent 6,247,995)
White trigger preparations for improving the signal detection in bioluminescent and chemiluminescent reactions (United States Patent 6,197,594)
Bioluminescent novelty items (United States Patent 6,152,358)
Bioluminescent bioreporter integrated circuit (United States Patent 6,117,643)
Bioluminescent novelty items (United States Patent 6,113,886)
Bioluminescent reporter bacterium (United States Patent 6,110,661)
Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein (United States Patent 6,074,859)
Bioluminescent adenosine phosphate ester assay and reagent (United States Patent 5,891,659)
Bioluminescent novelty items (United States Patent 5,876,995)
Bioluminescence measurement system (United States Patent 5,866,348)
Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method (United States Patent 5,843,746)
Bioluminescent bioassay system (United States Patent 5,840,572)
Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method (United States Patent 5,814,465)
Reagents and methods for use in bioluminescence (United States Patent 5,770,391)
Lyophilized bioluminescent bacterial reagent for the detection of toxicants (United States Patent 5,731,163)
Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells (United States Patent 5,714,666)
Modified bioluminescent proteins and their use (United States Patent 5,683,888)
Bioluminescence measurement system (United States Patent 5,618,682)
Bioluminescent bioassay system (United States Patent 5,565,360)
Bioluminescent algae in light bulb shaped viewing device (United States Patent 5,554,035)
Modified apoaequorin having increased bioluminescent activity (United States Patent 5,541,309)
Modified apoaequorin having increased bioluminescent activity (United States Patent 5,360,728)
Bioluminescence method for the determination of pesticides (United States Patent 5,283,180)
Bioluminescence bathyphotometer (United States Patent 5,264,906)
Automated bioluminescence microbial monitor (United States Patent 5,141,869)
Stress-resistant bioluminescent dinoflagellates (United States Patent 5,130,251)
Apparatus for bioluminescence measurement (United States Patent 5,112,646)
Bioluminescent detector (United States Patent 4,978,854)
Microbiological assay using bioluminescent organism (United States Patent 4,950,594)
Support used in bioluminescent dosing of enzymes, substrates or enzymatic inhibitors (United States Patent 4,927,752)
Measuring instrument for bioluminescence and chemilumnescence or turbidimetry (United States Patent 4,863,690)
Detection and/or identification of microorganisms in a test sample using bioluminescence or other exogenous genetically-introduced marker (United States Patent 4,861,709)
Bioluminescent simulator and method (United States Patent 4,697,374)
Bioluminescent assay reagent and method (United States Patent 4,665,022)
Bioluminescent tracer composition and method of use in immunoassays (United States Patent 4,604,364)
System for measuring bioluminescence flash kinetics (United States Patent 4,563,331)
Bioluminescence method for determining NADH or NADPH (United States Patent 4,501,813)
Bioluminescence methods for enzymatic determinations (United States Patent 4,357,420)
Instrument for chemi- or bioluminescent analysis (United States Patent 4,329,316)
Assaying of digoxin by means of bioluminescence and inhibition of NA.sup.+ - .sup.+ -ATPase (United States Patent 4,264,727)
Method and reagent for bioluminiscence (United States Patent 4,246,340)
Bioluminescent sensor system (United States Patent 3,958,938)
Bioluminescent protease assay (United States Patent 7,148,030)
Bioluminescence regenerative cycle (BRC) for nucleic acid quantification (United States Patent 7,141,370)
Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen (United States Patent 7,090,992)
Transgenic bioluminescent plants (United States Patent 7,049,483)
Sample collection and bioluminescent sample testing system (United States Patent 7,030,403)
Bioluminescent assays and bacterial strains useful therein (United States Patent 6,956,113)
Chimeric GFP-aequorin as bioluminescent Ca++reporters at the single cell level (United States Patent 6,936,475)
Methods and apparatus to improve the sensitivity and reproducibility of bioluminescent analytical methods (United States Patent 6,927,851)
Bioluminescent bioreporter integrated circuit detection methods (United States Patent 6,905,834)
Chimeric GFP-aequorin as bioluminescent Ca++ reporters at the single cell level (United States Patent 6,800,492)
Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses (United States Patent 6,689,391)
Bioluminescent biosensor device (United States Patent 6,544,729)
Method of making bioluminescent assay reagent based on non-viable E. coli (United States Patent 6,524,810)
Luminescent tool, its auxiliary member and method of preserving bioluminescent composition used in the tool and the auxiliary member (United States Patent 6,521,304)
Modified bioluminescent proteins and their use (United States Patent 6,492,500)
Method for rapidly detecting and enumerating microorganisms in mammalian cell preparations using ATP bioluminescence (United States Patent 6,465,201)
Modified bioluminescent proteins and their use (United States Patent 6,440,665)
Bioluminescent novelty items (United States Patent 6,247,995)
White trigger preparations for improving the signal detection in bioluminescent and chemiluminescent reactions (United States Patent 6,197,594)
Bioluminescent novelty items (United States Patent 6,152,358)
Bioluminescent bioreporter integrated circuit (United States Patent 6,117,643)
Bioluminescent novelty items (United States Patent 6,113,886)
Bioluminescent reporter bacterium (United States Patent 6,110,661)
Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein (United States Patent 6,074,859)
Bioluminescent adenosine phosphate ester assay and reagent (United States Patent 5,891,659)
Bioluminescent novelty items (United States Patent 5,876,995)
Bioluminescence measurement system (United States Patent 5,866,348)
Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method (United States Patent 5,843,746)
Bioluminescent bioassay system (United States Patent 5,840,572)
Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method (United States Patent 5,814,465)
Reagents and methods for use in bioluminescence (United States Patent 5,770,391)
Lyophilized bioluminescent bacterial reagent for the detection of toxicants (United States Patent 5,731,163)
Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells (United States Patent 5,714,666)
Modified bioluminescent proteins and their use (United States Patent 5,683,888)
Bioluminescence measurement system (United States Patent 5,618,682)
Bioluminescent bioassay system (United States Patent 5,565,360)
Bioluminescent algae in light bulb shaped viewing device (United States Patent 5,554,035)
Modified apoaequorin having increased bioluminescent activity (United States Patent 5,541,309)
Modified apoaequorin having increased bioluminescent activity (United States Patent 5,360,728)
Bioluminescence method for the determination of pesticides (United States Patent 5,283,180)
Bioluminescence bathyphotometer (United States Patent 5,264,906)
Automated bioluminescence microbial monitor (United States Patent 5,141,869)
Stress-resistant bioluminescent dinoflagellates (United States Patent 5,130,251)
Apparatus for bioluminescence measurement (United States Patent 5,112,646)
Bioluminescent detector (United States Patent 4,978,854)
Microbiological assay using bioluminescent organism (United States Patent 4,950,594)
Support used in bioluminescent dosing of enzymes, substrates or enzymatic inhibitors (United States Patent 4,927,752)
Measuring instrument for bioluminescence and chemilumnescence or turbidimetry (United States Patent 4,863,690)
Detection and/or identification of microorganisms in a test sample using bioluminescence or other exogenous genetically-introduced marker (United States Patent 4,861,709)
Bioluminescent simulator and method (United States Patent 4,697,374)
Bioluminescent assay reagent and method (United States Patent 4,665,022)
Bioluminescent tracer composition and method of use in immunoassays (United States Patent 4,604,364)
System for measuring bioluminescence flash kinetics (United States Patent 4,563,331)
Bioluminescence method for determining NADH or NADPH (United States Patent 4,501,813)
Bioluminescence methods for enzymatic determinations (United States Patent 4,357,420)
Instrument for chemi- or bioluminescent analysis (United States Patent 4,329,316)
Assaying of digoxin by means of bioluminescence and inhibition of NA.sup.+ - .sup.+ -ATPase (United States Patent 4,264,727)
Method and reagent for bioluminiscence (United States Patent 4,246,340)
Bioluminescent sensor system (United States Patent 3,958,938)
Bioluminescent protease assay (United States Patent 7,148,030)
Bioluminescence regenerative cycle (BRC) for nucleic acid quantification (United States Patent 7,141,370)
Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen (United States Patent 7,090,992)
Transgenic bioluminescent plants (United States Patent 7,049,483)
Sample collection and bioluminescent sample testing system (United States Patent 7,030,403)
Bioluminescent assays and bacterial strains useful therein (United States Patent 6,956,113)
Chimeric GFP-aequorin as bioluminescent Ca++reporters at the single cell level (United States Patent 6,936,475)
Methods and apparatus to improve the sensitivity and reproducibility of bioluminescent analytical methods (United States Patent 6,927,851)
Bioluminescent bioreporter integrated circuit detection methods (United States Patent 6,905,834)
Chimeric GFP-aequorin as bioluminescent Ca++ reporters at the single cell level (United States Patent 6,800,492)
Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses (United States Patent 6,689,391)
Bioluminescent biosensor device (United States Patent 6,544,729)
Method of making bioluminescent assay reagent based on non-viable E. coli (United States Patent 6,524,810)
Luminescent tool, its auxiliary member and method of preserving bioluminescent composition used in the tool and the auxiliary member (United States Patent 6,521,304)
Modified bioluminescent proteins and their use (United States Patent 6,492,500)
Method for rapidly detecting and enumerating microorganisms in mammalian cell preparations using ATP bioluminescence (United States Patent 6,465,201)
Modified bioluminescent proteins and their use (United States Patent 6,440,665)
Bioluminescent novelty items (United States Patent 6,247,995)
White trigger preparations for improving the signal detection in bioluminescent and chemiluminescent reactions (United States Patent 6,197,594)
Bioluminescent novelty items (United States Patent 6,152,358)
Bioluminescent bioreporter integrated circuit (United States Patent 6,117,643)
Bioluminescent novelty items (United States Patent 6,113,886)
Bioluminescent reporter bacterium (United States Patent 6,110,661)
Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein (United States Patent 6,074,859)
Bioluminescent adenosine phosphate ester assay and reagent (United States Patent 5,891,659)
Bioluminescent novelty items (United States Patent 5,876,995)
Bioluminescence measurement system (United States Patent 5,866,348)
Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method (United States Patent 5,843,746)
Bioluminescent bioassay system (United States Patent 5,840,572)
Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method (United States Patent 5,814,465)
Reagents and methods for use in bioluminescence (United States Patent 5,770,391)
Lyophilized bioluminescent bacterial reagent for the detection of toxicants (United States Patent 5,731,163)
Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells (United States Patent 5,714,666)
Modified bioluminescent proteins and their use (United States Patent 5,683,888)
Bioluminescence measurement system (United States Patent 5,618,682)
Bioluminescent bioassay system (United States Patent 5,565,360)
Bioluminescent algae in light bulb shaped viewing device (United States Patent 5,554,035)
Modified apoaequorin having increased bioluminescent activity (United States Patent 5,541,309)
Modified apoaequorin having increased bioluminescent activity (United States Patent 5,360,728)
Bioluminescence method for the determination of pesticides (United States Patent 5,283,180)
Bioluminescence bathyphotometer (United States Patent 5,264,906)
Automated bioluminescence microbial monitor (United States Patent 5,141,869)
Stress-resistant bioluminescent dinoflagellates (United States Patent 5,130,251)
Apparatus for bioluminescence measurement (United States Patent 5,112,646)
Bioluminescent detector (United States Patent 4,978,854)
Microbiological assay using bioluminescent organism (United States Patent 4,950,594)
Support used in bioluminescent dosing of enzymes, substrates or enzymatic inhibitors (United States Patent 4,927,752)
Measuring instrument for bioluminescence and chemilumnescence or turbidimetry (United States Patent 4,863,690)
Detection and/or identification of microorganisms in a test sample using bioluminescence or other exogenous genetically-introduced marker (United States Patent 4,861,709)
Bioluminescent simulator and method (United States Patent 4,697,374)
Bioluminescent assay reagent and method (United States Patent 4,665,022)
Bioluminescent tracer composition and method of use in immunoassays (United States Patent 4,604,364)
System for measuring bioluminescence flash kinetics (United States Patent 4,563,331)
Bioluminescence method for determining NADH or NADPH (United States Patent 4,501,813)
Bioluminescence methods for enzymatic determinations (United States Patent 4,357,420)
Instrument for chemi- or bioluminescent analysis (United States Patent 4,329,316)
Assaying of digoxin by means of bioluminescence and inhibition of NA.sup.+ - .sup.+ -ATPase (United States Patent 4,264,727)
Method and reagent for bioluminiscence (United States Patent 4,246,340)
Bioluminescent sensor system (United States Patent 3,958,938)
Bioluminescent protease assay (United States Patent 7,148,030)
Bioluminescence regenerative cycle (BRC) for nucleic acid quantification (United States Patent 7,141,370)
Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen (United States Patent 7,090,992)
Transgenic bioluminescent plants (United States Patent 7,049,483)
Sample collection and bioluminescent sample testing system (United States Patent 7,030,403)
Bioluminescent assays and bacterial strains useful therein (United States Patent 6,956,113)
Chimeric GFP-aequorin as bioluminescent Ca++reporters at the single cell level (United States Patent 6,936,475)
Methods and apparatus to improve the sensitivity and reproducibility of bioluminescent analytical methods (United States Patent 6,927,851)
Bioluminescent bioreporter integrated circuit detection methods (United States Patent 6,905,834)
Chimeric GFP-aequorin as bioluminescent Ca++ reporters at the single cell level (United States Patent 6,800,492)
Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses (United States Patent 6,689,391)
Bioluminescent biosensor device (United States Patent 6,544,729)
Method of making bioluminescent assay reagent based on non-viable E. coli (United States Patent 6,524,810)
Luminescent tool, its auxiliary member and method of preserving bioluminescent composition used in the tool and the auxiliary member (United States Patent 6,521,304)
Modified bioluminescent proteins and their use (United States Patent 6,492,500)
Method for rapidly detecting and enumerating microorganisms in mammalian cell preparations using ATP bioluminescence (United States Patent 6,465,201)
Modified bioluminescent proteins and their use (United States Patent 6,440,665)
Bioluminescent novelty items (United States Patent 6,247,995)
White trigger preparations for improving the signal detection in bioluminescent and chemiluminescent reactions (United States Patent 6,197,594)
Bioluminescent novelty items (United States Patent 6,152,358)
Bioluminescent bioreporter integrated circuit (United States Patent 6,117,643)
Bioluminescent novelty items (United States Patent 6,113,886)
Bioluminescent reporter bacterium (United States Patent 6,110,661)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.