


Professor Demchick's Patent Services
Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)
PATENTS RELATED TO CHOLESTEROL Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.
Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.
If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.
The following sampling is to give you some sense of the types of cholesterol related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.
It should be noted that spelling, form and typographical errors in the original patents are preserved here.
(R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity (United States Patent 7,122,536)
Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses (United States Patent 7,119,221)
Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks (United States Patent 7,101,544)
Compositions of ezetimibe and methods for the treatment of cholesterol-associated benign and malignant tumors (United States Patent 7,098,198)
Method of treating disorder related to high cholesterol concentration (United States Patent 7,078,396)
Method for increasing HDL cholesterol level (United States Patent 7,074,407)
Method and composition for inhibiting cholesterol esterase (United States Patent 7,071,174)
Assay method for measurement of net cholesterol flux (United States Patent 7,060,452)
High-throughput screening assay for cholesterol inhibitors and inhibitors identified thereby (United States Patent 7,049,086)
.beta.-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same (United States Patent 7,045,515)
Low cholesterol, functional, animal muscle protein composition and process (United States Patent 7,033,636)
Cell culture system for determining the cholesterol efflux potential for serum (United States Patent 7,029,863)
Lactoferrin in the reduction of circulating cholesterol, vascular inflammation, atherosclerosis and cardiovascular disease (United States Patent 7,026,295)
Method for the simultaneous and direct determination of serum cholesterol in high and low density lipoproteins using infrared spectroscopy (United States Patent 7,022,527)
Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol (United States Patent 7,008,776)
Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 7,002,030)
Nutritional supplement for lowering serum triglyceride and cholesterol levels (United States Patent 6,998,501)
Method for decreasing cholesterol level in blood (United States Patent 6,998,397)
Methods for modulation of cholesterol transport (United States Patent 6,962,688)
Plan lecithin: cholesterol acyltransferases (United States Patent 6,940,003)
Test piece for assaying high density lipoprotein (HDL) cholesterol (United States Patent 6,939,682)
Compositions of ezetimibe and methods for the treatment of cholesterol-associated benign and malignant tumors (United States Patent 6,933,292)
Cholesterol lowering supplement (United States Patent 6,933,291)
4-Phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein (United States Patent 6,897,317)
Method for quantifying cholesterol in high density lipoprotein (United States Patent 6,893,832)
Methods and compositions to lower plasma cholesterol levels (United States Patent 6,887,712)
Pharmaceutical compositions containing 8-chloro-3 (.beta.-diethylaminoethyl)-4-methyl-7-ethoxycarbonylmethoxy coumarin base and the salts thereof with cholesterol-lowering activity (United States Patent 6,884,818)
Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality (United States Patent 6,881,860)
Combined cholesterol and bilirubin tests as risk predictors for coronary artery disease (United States Patent 6,869,802)
Food product suitable for reducing low density lipoprotein cholesterol levels (United States Patent 6,849,281)
Method to counter oxidation of LDL, decrease triglyceride or cholesterol and inhibit atherosclerosis using Hibiscus sabdariffa extract (United States Patent 6,849,278)
Compositions and methods of modulating cholesterol metabolism (United States Patent 6,835,866)
Synergistic effect of amlodipine and atorvastatin on cholesterol crystal formation inhibition and aortic endothelial cell nitric oxide release (United States Patent 6,835,742)
Compositions and methods for increasing cholesterol efflux and raising HDL ATP binding cassette transporter protein ABC1 (United States Patent 6,835,563)
Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter ABC1 (United States Patent 6,821,774)
Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same (United States Patent 6,818,414)
Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions (United States Patent 6,811,786)
Vertebrate intestinal protein which absorbs cholesterol, its inhibitors and mehtod of identifying the same (United States Patent 6,794,359)
Methods for fractional quatification of cholesterol in lipoproteins and quantification reagents (United States Patent 6,794,157)
Composition and method for lowering cholesterol (United States Patent 6,793,946)
Method and composition for regulation of blood cholesterol (United States Patent 6,787,162)
Composition for lowering blood cholesterol (United States Patent 6,787,151)
Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,770,768)
Method of determining cholesterol and sensor applicable to the same (United States Patent 6,762,062)
Compositions and methods for treating osteoporosis and lowering cholesterol (United States Patent 6,756,401)
Meat product having effect of inhibiting increase in blood cholesterol (United States Patent 6,749,884)
Compounds affecting cholesterol absorption (United States Patent 6,727,277)
Method to treat chronic heart failure and/or elevated cholesterol levels (United States Patent 6,716,877)
Uses of kombic acid as an anticancer and cholesterol-lowering agent (United States Patent 6,713,512)
Ether compounds and compositions for cholesterol management and related uses (United States Patent 6,713,507)
Compositions and methods for modulating serum cholesterol (United States Patent 6,713,057)
Sulfide and disulfide compounds and compositions for cholesterol management and related uses (United States Patent 6,703,422)
Ketone compounds and compositions for cholesterol management and related uses (United States Patent 6,699,910)
Cholesterol and triglyceride-modulating drugs and methods (United States Patent 6,683,104)
Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses (United States Patent 6,673,780)
Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin (United States Patent 6,669,955)
Composition containing isoflavone material and plant sterol for reducing LDL-cholesterol (United States Patent 6,669,952)
Egg yolk-containing, reduced-cholesterol, oil-in-water emulsified food and the preparation thereof (United States Patent 6,660,312)
Use of lecithin-cholesterol acyltransferase (LCAT) to reduce accumulation of cholesterol (United States Patent 6,635,614)
Method and composition for inhibiting human cholesterol esterase (United States Patent 6,632,801)
Method for preventing, stabilizing or causing regression of atherosclerosis employing a combination of a cholesterol lowering drug and an ace inhibitor (United States Patent 6,630,502)
Method of reducing cholesterol and altering fatty acid content of eggs (United States Patent 6,630,181)
Cationic amphiphiles of cholesterol (United States Patent 6,627,218)
Cholesterol lowering structured lipids containing omega 3 polyunsaturated fatty acids and their process thereof (United States Patent 6,608,223)
Hydrazones and analogs as cholesterol lowering agents (United States Patent 6,605,615)
Hypertension-treatment and cholesterol-depressant composition comprising extract from mixture of Panax notoginseng and Salvia miltiorrhiza and method of preparing the same (United States Patent 6,589,572)
Composition containing soy hypocotyl material and plant sterol for reducing LDL-cholesterol (United States Patent 6,579,534)
Cholesterol lowering beverage (United States Patent 6,576,285)
Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin (United States Patent 6,576,256)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,576,242)
Administering a composition containing plant sterol, soy protein and isoflavone for reducing LDL-cholesterol (United States Patent 6,572,876)
Elevation of HDL cholesterol by 4-[(aminothioxomethyl)-hydrazono]-N-(substituted)-4-arylbutanamides (United States Patent 6,566,375)
Cholesterol treatment formulation (United States Patent 6,565,896)
4-phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein (United States Patent 6,562,976)
Cholesterol 25-hydroxylase (United States Patent 6,562,609)
Method of treating high plasma cholesterol levels (United States Patent 6,562,329)
Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,544,973)
Composition containing plant sterol, soy protein and isoflavone for reducing LDL cholesterol (United States Patent 6,544,566)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,544,525)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,541,006)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,541,005)
Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same (United States Patent 6,534,676)
Methods for treating cholesterol-containing foodstuffs using live ciliates (United States Patent 6,534,100)
Genes and proteins controlling cholesterol synthesis (United States Patent 6,531,292)
Synthetic peptides that enhance atherogenic lipoprotein uptake and lower plasma cholesterol (United States Patent 6,506,880)
Methods and compositions for reducing cholesterol levels using a proanthocyanidin and niacin-bound chromium complex (United States Patent 6,500,469)
Lecithin-cholesterol acyltransferase protein (United States Patent 6,498,019)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,495,173)
Cholesterol lowering composition (United States Patent 6,491,952)
CHOLESTEROL DEHYDROGENASE, COPROSTAN-3-ONE DEHYDROGENASE AND 4-CHOLESTEN-3-ONE DEHYDROGENASE, COMPOSITIONS CONTAINING THE DEHYDROGENASES, AND METHOD FOR REDUCING AMOUNT OF CHOLESTEROL USING THE COMPOSITIONS (United States Patent 6,485,931)
Method of determining cholesterol content of high-density lipoproteins (United States Patent 6,479,249)
FXR receptor-mediated modulation cholesterol metabolism (United States Patent 6,465,258)
Acyl CoA: cholesterol acyltransferase related nucleic acid sequences (United States Patent 6,444,876)
Method of reducing cholesterol in chicken eggs (United States Patent 6,436,451)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,436,406)
Cholesterol oxidase (United States Patent 6,410,253)
Carborane containing cholesterol, a new type of molecule for targeted boron drug delivery (United States Patent 6,392,068)
Method of reducing cholesterol in eggs (United States Patent 6,391,348)
Benzene compounds as antiproliferative and cholesterol lowering agents (United States Patent 6,388,131)
(R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity (United States Patent 7,122,536)
Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses (United States Patent 7,119,221)
Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks (United States Patent 7,101,544)
Compositions of ezetimibe and methods for the treatment of cholesterol-associated benign and malignant tumors (United States Patent 7,098,198)
Method of treating disorder related to high cholesterol concentration (United States Patent 7,078,396)
Method for increasing HDL cholesterol level (United States Patent 7,074,407)
Method and composition for inhibiting cholesterol esterase (United States Patent 7,071,174)
Assay method for measurement of net cholesterol flux (United States Patent 7,060,452)
High-throughput screening assay for cholesterol inhibitors and inhibitors identified thereby (United States Patent 7,049,086)
.beta.-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same (United States Patent 7,045,515)
Low cholesterol, functional, animal muscle protein composition and process (United States Patent 7,033,636)
Cell culture system for determining the cholesterol efflux potential for serum (United States Patent 7,029,863)
Lactoferrin in the reduction of circulating cholesterol, vascular inflammation, atherosclerosis and cardiovascular disease (United States Patent 7,026,295)
Method for the simultaneous and direct determination of serum cholesterol in high and low density lipoproteins using infrared spectroscopy (United States Patent 7,022,527)
Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol (United States Patent 7,008,776)
Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 7,002,030)
Nutritional supplement for lowering serum triglyceride and cholesterol levels (United States Patent 6,998,501)
Method for decreasing cholesterol level in blood (United States Patent 6,998,397)
Methods for modulation of cholesterol transport (United States Patent 6,962,688)
Plan lecithin: cholesterol acyltransferases (United States Patent 6,940,003)
Test piece for assaying high density lipoprotein (HDL) cholesterol (United States Patent 6,939,682)
Compositions of ezetimibe and methods for the treatment of cholesterol-associated benign and malignant tumors (United States Patent 6,933,292)
Cholesterol lowering supplement (United States Patent 6,933,291)
4-Phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein (United States Patent 6,897,317)
Method for quantifying cholesterol in high density lipoprotein (United States Patent 6,893,832)
Methods and compositions to lower plasma cholesterol levels (United States Patent 6,887,712)
Pharmaceutical compositions containing 8-chloro-3 (.beta.-diethylaminoethyl)-4-methyl-7-ethoxycarbonylmethoxy coumarin base and the salts thereof with cholesterol-lowering activity (United States Patent 6,884,818)
Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality (United States Patent 6,881,860)
Combined cholesterol and bilirubin tests as risk predictors for coronary artery disease (United States Patent 6,869,802)
Food product suitable for reducing low density lipoprotein cholesterol levels (United States Patent 6,849,281)
Method to counter oxidation of LDL, decrease triglyceride or cholesterol and inhibit atherosclerosis using Hibiscus sabdariffa extract (United States Patent 6,849,278)
Compositions and methods of modulating cholesterol metabolism (United States Patent 6,835,866)
Synergistic effect of amlodipine and atorvastatin on cholesterol crystal formation inhibition and aortic endothelial cell nitric oxide release (United States Patent 6,835,742)
Compositions and methods for increasing cholesterol efflux and raising HDL ATP binding cassette transporter protein ABC1 (United States Patent 6,835,563)
Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter ABC1 (United States Patent 6,821,774)
Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same (United States Patent 6,818,414)
Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions (United States Patent 6,811,786)
Vertebrate intestinal protein which absorbs cholesterol, its inhibitors and mehtod of identifying the same (United States Patent 6,794,359)
Methods for fractional quatification of cholesterol in lipoproteins and quantification reagents (United States Patent 6,794,157)
Composition and method for lowering cholesterol (United States Patent 6,793,946)
Method and composition for regulation of blood cholesterol (United States Patent 6,787,162)
Composition for lowering blood cholesterol (United States Patent 6,787,151)
Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,770,768)
Method of determining cholesterol and sensor applicable to the same (United States Patent 6,762,062)
Compositions and methods for treating osteoporosis and lowering cholesterol (United States Patent 6,756,401)
Meat product having effect of inhibiting increase in blood cholesterol (United States Patent 6,749,884)
Compounds affecting cholesterol absorption (United States Patent 6,727,277)
Method to treat chronic heart failure and/or elevated cholesterol levels (United States Patent 6,716,877)
Uses of kombic acid as an anticancer and cholesterol-lowering agent (United States Patent 6,713,512)
Ether compounds and compositions for cholesterol management and related uses (United States Patent 6,713,507)
Compositions and methods for modulating serum cholesterol (United States Patent 6,713,057)
Sulfide and disulfide compounds and compositions for cholesterol management and related uses (United States Patent 6,703,422)
Ketone compounds and compositions for cholesterol management and related uses (United States Patent 6,699,910)
Cholesterol and triglyceride-modulating drugs and methods (United States Patent 6,683,104)
Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses (United States Patent 6,673,780)
Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin (United States Patent 6,669,955)
Composition containing isoflavone material and plant sterol for reducing LDL-cholesterol (United States Patent 6,669,952)
Egg yolk-containing, reduced-cholesterol, oil-in-water emulsified food and the preparation thereof (United States Patent 6,660,312)
Use of lecithin-cholesterol acyltransferase (LCAT) to reduce accumulation of cholesterol (United States Patent 6,635,614)
Method and composition for inhibiting human cholesterol esterase (United States Patent 6,632,801)
Method for preventing, stabilizing or causing regression of atherosclerosis employing a combination of a cholesterol lowering drug and an ace inhibitor (United States Patent 6,630,502)
Method of reducing cholesterol and altering fatty acid content of eggs (United States Patent 6,630,181)
Cationic amphiphiles of cholesterol (United States Patent 6,627,218)
Cholesterol lowering structured lipids containing omega 3 polyunsaturated fatty acids and their process thereof (United States Patent 6,608,223)
Hydrazones and analogs as cholesterol lowering agents (United States Patent 6,605,615)
Hypertension-treatment and cholesterol-depressant composition comprising extract from mixture of Panax notoginseng and Salvia miltiorrhiza and method of preparing the same (United States Patent 6,589,572)
Composition containing soy hypocotyl material and plant sterol for reducing LDL-cholesterol (United States Patent 6,579,534)
Cholesterol lowering beverage (United States Patent 6,576,285)
Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin (United States Patent 6,576,256)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,576,242)
Administering a composition containing plant sterol, soy protein and isoflavone for reducing LDL-cholesterol (United States Patent 6,572,876)
Elevation of HDL cholesterol by 4-[(aminothioxomethyl)-hydrazono]-N-(substituted)-4-arylbutanamides (United States Patent 6,566,375)
Cholesterol treatment formulation (United States Patent 6,565,896)
4-phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein (United States Patent 6,562,976)
Cholesterol 25-hydroxylase (United States Patent 6,562,609)
Method of treating high plasma cholesterol levels (United States Patent 6,562,329)
Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,544,973)
Composition containing plant sterol, soy protein and isoflavone for reducing LDL cholesterol (United States Patent 6,544,566)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,544,525)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,541,006)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,541,005)
Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same (United States Patent 6,534,676)
Methods for treating cholesterol-containing foodstuffs using live ciliates (United States Patent 6,534,100)
Genes and proteins controlling cholesterol synthesis (United States Patent 6,531,292)
Synthetic peptides that enhance atherogenic lipoprotein uptake and lower plasma cholesterol (United States Patent 6,506,880)
Methods and compositions for reducing cholesterol levels using a proanthocyanidin and niacin-bound chromium complex (United States Patent 6,500,469)
Lecithin-cholesterol acyltransferase protein (United States Patent 6,498,019)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,495,173)
Cholesterol lowering composition (United States Patent 6,491,952)
CHOLESTEROL DEHYDROGENASE, COPROSTAN-3-ONE DEHYDROGENASE AND 4-CHOLESTEN-3-ONE DEHYDROGENASE, COMPOSITIONS CONTAINING THE DEHYDROGENASES, AND METHOD FOR REDUCING AMOUNT OF CHOLESTEROL USING THE COMPOSITIONS (United States Patent 6,485,931)
Method of determining cholesterol content of high-density lipoproteins (United States Patent 6,479,249)
FXR receptor-mediated modulation cholesterol metabolism (United States Patent 6,465,258)
Acyl CoA: cholesterol acyltransferase related nucleic acid sequences (United States Patent 6,444,876)
Method of reducing cholesterol in chicken eggs (United States Patent 6,436,451)
Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis (United States Patent 6,436,406)
Cholesterol oxidase (United States Patent 6,410,253)
Carborane containing cholesterol, a new type of molecule for targeted boron drug delivery (United States Patent 6,392,068)
Method of reducing cholesterol in eggs (United States Patent 6,391,348)
Benzene compounds as antiproliferative and cholesterol lowering agents (United States Patent 6,388,131)
(R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity (United States Patent 7,122,536)
Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses (United States Patent 7,119,221)
Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.