


Professor Demchick's Patent Services
Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)
PATENTS RELATED TO ESCHERICHIA Although Dr. Demchick also represents patent seekers with non-microbiological inventions, his doctorate is in microbiology. Microbiology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving microbiology.
Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.
If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.
The following sampling is to give you some sense of the types of escherichia related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.
It should be noted that spelling, form and typographical errors in the original patents are preserved here.
Nucleic acids encoding novel proteins in enteroaggregative Escherichia coli (EAEC) (United States Patent 7,141,662)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 7,138,266)
Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate (United States Patent 7,135,316)
Sequences for the detection of Escherichia coli (United States Patent 7,125,661)
Proteins in enteroaggregative Escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections (United States Patent 7,090,850)
Lactobacillus paracasei subsp. paracasei strain antibacterial against Helicobacter pylori and Escherichia coli 0157:h7 (United States Patent 7,090,840)
Nucleic acids encoding novel proteins in enteroaggregative escherichia coli (EAEC) (United States Patent 7,087,741)
Proteins in enteroaggregative escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections (United States Patent 7,087,230)
Pathogenic Escherichia coli associated protein espA (United States Patent 7,078,193)
Escherichia coli strain secreting human granulocyte colony stimulating factor (G-CSF) (United States Patent 7,070,989)
L-arginine producing Escherichia coli and method of producing L-arginine (United States Patent 7,052,884)
Method for detecting Escherichia coli (United States Patent 7,041,811)
DNA coding for protein which confers on bacterium Escherichia coli resistance to L-homoserine, and method for producing L-amino acids (United States Patent 6,887,691)
Method for treating, preventing, or inhibiting enterotoxigenic Escherichia coli infections with bovine red blood cells (United States Patent 6,869,602)
Multiplex RT-PCR/PCR for simultaneous detection of bovine coronavirus, bovine rotavirus, Cryptosporidium parvum, and Escherichia coli (United States Patent 6,867,021)
Vaccines against Escherichia coli O157 infection (United States Patent 6,858,211)
Site-directed mutagenesis of Escherichia coli phytase (United States Patent 6,841,370)
L-arginine producing Escherichia coli and method of producing L-arginine (United States Patent 6,841,365)
Lipopolysaccharides (LPS) extracted from Escherichia coli (United States Patent 6,833,451)
Nucleotide sequence of Escherichia coli pathogenicity islands (United States Patent 6,787,643)
Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate (United States Patent 6,756,222)
Genes identified as required for proliferation in Escherichia coli (United States Patent 6,720,139)
Method, test media and chromogenic compounds for identifying and differentiating general coliforms and escherichia coli bacteria (United States Patent 6,699,685)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 6,653,111)
Enzymatic process for the preparation of cephalosporanic 7$B(G)-(4-Carboxybutanamide) acid by means of the modified enzyme D-aminoacid oxidase of trigonopsis variabilis produced in escherichia coli (United States Patent 6,635,458)
Escherichia coli secreted protein B (United States Patent 6,635,259)
Anti-idiotypic antibody against FimH adhesion of uropathogenic type I-fimbriated Escherichia coli, compositions containing same and method for using same (United States Patent 6,632,431)
Method for isolation and identification of Escherichia coli 0157:H7 and plating media for said process (United States Patent 6,617,149)
Oligonucleotide specific of the Escherichia coli species and method for detecting and displaying bacteria of this species (United States Patent 6,551,776)
Method for identifying Escherichia coli strain DSM 6601 (United States Patent 6,489,107)
Use of bacteriophages for control of escherichia coli O157 (United States Patent 6,485,902)
Pta LDHA double mutant Escherichia coli SS373 and the method of producing succinic acid therefrom (United States Patent 6,448,061)
Compositions for treating Escherichia coli urinary tract infections (United States Patent 6,432,681)
Pharmaceutical composition of escherichia coli heat-labile enterotoxin adjuvant and methods of use (United States Patent 6,413,523)
Secretion of T cell receptor fragments from recombinant Escherichia coli cells (United States Patent 6,399,368)
Pathogenic Escherichia coli associated protein EspA (United States Patent 6,355,254)
Nucleotide sequence of Escherichia coli pathogenicity islands (United States Patent 6,316,609)
DNA coding for protein which confers on bacterium escherichia coli resistance to L-homoserine and method for producing L-amino acids (United States Patent 6,303,348)
Escherichia coli strain and method for producing L-threonine (United States Patent 6,297,031)
Treatment of diarrhea caused by enteropathogenic Escherichia coli (United States Patent 6,291,435)
Expression vectors encoding Escherichia coli OmpC as a cell surface anchoring motif (United States Patent 6,274,345)
Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof (United States Patent 6,268,471)
Escherichia coli CSRB gene and RNA encoded thereby (United States Patent 6,228,638)
Rapid Identification of Escherichia coli O157:H7 (United States Patent 6,210,911)
Amplification and detection of shigella spp. and enteroinvasive strains of Escherichia coli (United States Patent 6,207,818)
Fusion protein systems designed to increase soluble cytoplasmic expression of heterologous proteins in Escherichia coli (United States Patent 6,207,420)
Immunodiagnostic test for enterohemorrhagic Escherichia coli infection (United States Patent 6,204,004)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 6,165,756)
Method for the production of anti-escherichia. coli O157 : H7 antibody (United States Patent 6,162,441)
Method for determining susceptibility to Escherichia coli urinary tract infections, method for diagnosing secretors and nonsecretors, and method and medicament for preventing Escherichia coli urinary tract infections (United States Patent 6,130,205)
Method for inhibiting production of toxins from enteropathogenic escherichia coli, and butyric-acid bacteria and butyric-acid bacteria containing pharmaceuticals used in combination with antibiotics for the method (United States Patent 6,099,833)
Pathogenicity and protective attributes of major clones of Escherichia coli recovered from chickens during processing (United States Patent 6,096,322)
Method for isolation and identification of Escherichia coli 0157:H7 and plating media for said process (United States Patent 6,087,156)
High expression Escherichia coli expression vector (United States Patent 6,068,991)
Amplification and detection of shigella spp. and enteroinvasive strains of Escherichia coli (United States Patent 6,060,252)
Escherichia coli O157:H7 epithelial adhesion and vaccine (United States Patent 6,040,421)
Gene sequence of Aquifex pyrophilus superoxide dismutase and protein expressed in Escherichia coli (United States Patent 6,033,889)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 5,976,843)
Automated high-yield fermentation of plasmid DNA in Escherichia coli (United States Patent 5,955,323)
Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production (United States Patent 5,939,307)
Escherichia coli K-12 strains for production of recombinant proteins (United States Patent 5,932,439)
Campylobacteri jejuni flagellin-escherichia coli LT-B fusion protein (United States Patent 5,888,810)
Melanin production from transformed escherichia coli (United States Patent 5,837,505)
Shuttle vectors for Escherichia coli and cyanobateria (United States Patent 5,821,119)
Escherichia coli O157:H7 epithelial adhesin (United States Patent 5,798,260)
Probe for diagnosing Escherichia coli, Klebsiella pneumonieae or Enterobacter cloacae (United States Patent 5,763,188)
Production of tryptophan by the bacterium Escherichia coli (United States Patent 5,756,345)
Escherichia coli vaccine (United States Patent 5,750,115)
Detection of shiga-like toxins of enterohemoragic Escherichia coli (United States Patent 5,747,272)
Genetic markers and methods for the detection of escherichia coli serotype-0157:H7 (United States Patent 5,747,257)
Bacterial strain of escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 5,705,371)
Expression of biologically active human C-reactive protein in escherichia coli (United States Patent 5,702,921)
Nucleic acid probes and methods for detecting Escherichia coli (United States Patent 5,693,469)
Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof (United States Patent 5,684,144)
DNA polymerase III holoenzyme from Escherichia coli (United States Patent 5,668,004)
Strains of Escherichia coli which produce isoleucine or valine and a method for their production (United States Patent 5,658,766)
Assay for enterohemorrhagic Escherichia coli 0157:H7 by the polymerase chain reaction (United States Patent 5,652,102)
Escherichia coli strain 364 and use of said strain as a vaccine (United States Patent 5,641,491)
Bacterial strain of Escherichia coli VNII genetika 472T23 as the producer of L-threonine (United States Patent 5,631,157)
Enzyme-capture assay (ECA) for the identification of Escherichia coli in clinical samples (United States Patent 5,612,186)
Escherichia coli containing a gene encoding a maltogenic amylase BLMA of Bacillus licheniformis and gene product produced by same (United States Patent 5,583,039)
Method and colicin composition for inhibiting Escherichia coli 0157:H7 in food products (United States Patent 5,549,895)
Bacterial strain of escherichia coli BKIIM B-3996 as the producer of l-threonine (United States Patent 5,538,873)
Production of isoleucine by escherichia coli having isoleucine auxotrophy and no negative feedback inhibition of isoleucine production (United States Patent 5,534,421)
Regulation of Escherichia coli and other microorganisms through magnetic water treatment (United States Patent 5,534,156)
Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-beta-hydroxybutyrate biosynthetic pathway (United States Patent 5,518,907)
Method for the improved production and recovery of poly-.beta.-hydroxybutyrate from transformed Escherichia coli (United States Patent 5,512,456)
Process for the production of L-threonine and L-isoleucine by fermentation of Escherichia coli (United States Patent 5,474,918)
Reverse transcriptases from Escherichia coli and Myxococcus xanthus (United States Patent 5,434,070)
Mutant Escherichia coli capable of enhanced L-glutamic acid production (United States Patent 5,393,671)
Test media for identifying and differentiating general coliforms and Escherichia coli bacteria (United States Patent 5,393,662)
Mutant Escherichia coli capable of enhanced L-glutamic acid production by fermentation (United States Patent 5,378,616)
Method for determining susceptibility to escherichia coli urinary tract infections and method for diagnosing secretors and nonsecretors (United States Patent 5,374,532)
Escherichia coliO-polysaccharide-protein conjugate vaccine (United States Patent 5,370,872)
Method, test media and chromogenic compounds for identifying and differentiating general coliforms and Escherichia coli bacteria (United States Patent 5,358,854)
Monoclonal antibody to enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 and method for detection (United States Patent 5,354,661)
Production of poly-beta-hydroxybutyrate in transformed escherichia coli (United States Patent 5,334,520)
Process for producing foreign protein in Escherichia coli (United States Patent 5,304,471)
Cloned tyrosine phenol-lyase gene, recombinant plasmid containing the same and escherichia coli transformed with the same (United States Patent 5,260,198)
Method test media and chromogenic compounds for identifying and differentiating general coliforms and Escherichia coli bacteria (United States Patent 5,210,022)
Nucleic acids encoding novel proteins in enteroaggregative Escherichia coli (EAEC) (United States Patent 7,141,662)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 7,138,266)
Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate (United States Patent 7,135,316)
Sequences for the detection of Escherichia coli (United States Patent 7,125,661)
Proteins in enteroaggregative Escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections (United States Patent 7,090,850)
Lactobacillus paracasei subsp. paracasei strain antibacterial against Helicobacter pylori and Escherichia coli 0157:h7 (United States Patent 7,090,840)
Nucleic acids encoding novel proteins in enteroaggregative escherichia coli (EAEC) (United States Patent 7,087,741)
Proteins in enteroaggregative escherichia coli (EAEC) useful for diagnosis and therapy of EAEC infections (United States Patent 7,087,230)
Pathogenic Escherichia coli associated protein espA (United States Patent 7,078,193)
Escherichia coli strain secreting human granulocyte colony stimulating factor (G-CSF) (United States Patent 7,070,989)
L-arginine producing Escherichia coli and method of producing L-arginine (United States Patent 7,052,884)
Method for detecting Escherichia coli (United States Patent 7,041,811)
DNA coding for protein which confers on bacterium Escherichia coli resistance to L-homoserine, and method for producing L-amino acids (United States Patent 6,887,691)
Method for treating, preventing, or inhibiting enterotoxigenic Escherichia coli infections with bovine red blood cells (United States Patent 6,869,602)
Multiplex RT-PCR/PCR for simultaneous detection of bovine coronavirus, bovine rotavirus, Cryptosporidium parvum, and Escherichia coli (United States Patent 6,867,021)
Vaccines against Escherichia coli O157 infection (United States Patent 6,858,211)
Site-directed mutagenesis of Escherichia coli phytase (United States Patent 6,841,370)
L-arginine producing Escherichia coli and method of producing L-arginine (United States Patent 6,841,365)
Lipopolysaccharides (LPS) extracted from Escherichia coli (United States Patent 6,833,451)
Nucleotide sequence of Escherichia coli pathogenicity islands (United States Patent 6,787,643)
Escherichia coli having accession No. PTA 1579 and its use to produce polyhydroxybutyrate (United States Patent 6,756,222)
Genes identified as required for proliferation in Escherichia coli (United States Patent 6,720,139)
Method, test media and chromogenic compounds for identifying and differentiating general coliforms and escherichia coli bacteria (United States Patent 6,699,685)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 6,653,111)
Enzymatic process for the preparation of cephalosporanic 7$B(G)-(4-Carboxybutanamide) acid by means of the modified enzyme D-aminoacid oxidase of trigonopsis variabilis produced in escherichia coli (United States Patent 6,635,458)
Escherichia coli secreted protein B (United States Patent 6,635,259)
Anti-idiotypic antibody against FimH adhesion of uropathogenic type I-fimbriated Escherichia coli, compositions containing same and method for using same (United States Patent 6,632,431)
Method for isolation and identification of Escherichia coli 0157:H7 and plating media for said process (United States Patent 6,617,149)
Oligonucleotide specific of the Escherichia coli species and method for detecting and displaying bacteria of this species (United States Patent 6,551,776)
Method for identifying Escherichia coli strain DSM 6601 (United States Patent 6,489,107)
Use of bacteriophages for control of escherichia coli O157 (United States Patent 6,485,902)
Pta LDHA double mutant Escherichia coli SS373 and the method of producing succinic acid therefrom (United States Patent 6,448,061)
Compositions for treating Escherichia coli urinary tract infections (United States Patent 6,432,681)
Pharmaceutical composition of escherichia coli heat-labile enterotoxin adjuvant and methods of use (United States Patent 6,413,523)
Secretion of T cell receptor fragments from recombinant Escherichia coli cells (United States Patent 6,399,368)
Pathogenic Escherichia coli associated protein EspA (United States Patent 6,355,254)
Nucleotide sequence of Escherichia coli pathogenicity islands (United States Patent 6,316,609)
DNA coding for protein which confers on bacterium escherichia coli resistance to L-homoserine and method for producing L-amino acids (United States Patent 6,303,348)
Escherichia coli strain and method for producing L-threonine (United States Patent 6,297,031)
Treatment of diarrhea caused by enteropathogenic Escherichia coli (United States Patent 6,291,435)
Expression vectors encoding Escherichia coli OmpC as a cell surface anchoring motif (United States Patent 6,274,345)
Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof (United States Patent 6,268,471)
Escherichia coli CSRB gene and RNA encoded thereby (United States Patent 6,228,638)
Rapid Identification of Escherichia coli O157:H7 (United States Patent 6,210,911)
Amplification and detection of shigella spp. and enteroinvasive strains of Escherichia coli (United States Patent 6,207,818)
Fusion protein systems designed to increase soluble cytoplasmic expression of heterologous proteins in Escherichia coli (United States Patent 6,207,420)
Immunodiagnostic test for enterohemorrhagic Escherichia coli infection (United States Patent 6,204,004)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 6,165,756)
Method for the production of anti-escherichia. coli O157 : H7 antibody (United States Patent 6,162,441)
Method for determining susceptibility to Escherichia coli urinary tract infections, method for diagnosing secretors and nonsecretors, and method and medicament for preventing Escherichia coli urinary tract infections (United States Patent 6,130,205)
Method for inhibiting production of toxins from enteropathogenic escherichia coli, and butyric-acid bacteria and butyric-acid bacteria containing pharmaceuticals used in combination with antibiotics for the method (United States Patent 6,099,833)
Pathogenicity and protective attributes of major clones of Escherichia coli recovered from chickens during processing (United States Patent 6,096,322)
Method for isolation and identification of Escherichia coli 0157:H7 and plating media for said process (United States Patent 6,087,156)
High expression Escherichia coli expression vector (United States Patent 6,068,991)
Amplification and detection of shigella spp. and enteroinvasive strains of Escherichia coli (United States Patent 6,060,252)
Escherichia coli O157:H7 epithelial adhesion and vaccine (United States Patent 6,040,421)
Gene sequence of Aquifex pyrophilus superoxide dismutase and protein expressed in Escherichia coli (United States Patent 6,033,889)
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 5,976,843)
Automated high-yield fermentation of plasmid DNA in Escherichia coli (United States Patent 5,955,323)
Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production (United States Patent 5,939,307)
Escherichia coli K-12 strains for production of recombinant proteins (United States Patent 5,932,439)
Campylobacteri jejuni flagellin-escherichia coli LT-B fusion protein (United States Patent 5,888,810)
Melanin production from transformed escherichia coli (United States Patent 5,837,505)
Shuttle vectors for Escherichia coli and cyanobateria (United States Patent 5,821,119)
Escherichia coli O157:H7 epithelial adhesin (United States Patent 5,798,260)
Probe for diagnosing Escherichia coli, Klebsiella pneumonieae or Enterobacter cloacae (United States Patent 5,763,188)
Production of tryptophan by the bacterium Escherichia coli (United States Patent 5,756,345)
Escherichia coli vaccine (United States Patent 5,750,115)
Detection of shiga-like toxins of enterohemoragic Escherichia coli (United States Patent 5,747,272)
Genetic markers and methods for the detection of escherichia coli serotype-0157:H7 (United States Patent 5,747,257)
Bacterial strain of escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 5,705,371)
Expression of biologically active human C-reactive protein in escherichia coli (United States Patent 5,702,921)
Nucleic acid probes and methods for detecting Escherichia coli (United States Patent 5,693,469)
Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof (United States Patent 5,684,144)
DNA polymerase III holoenzyme from Escherichia coli (United States Patent 5,668,004)
Strains of Escherichia coli which produce isoleucine or valine and a method for their production (United States Patent 5,658,766)
Assay for enterohemorrhagic Escherichia coli 0157:H7 by the polymerase chain reaction (United States Patent 5,652,102)
Escherichia coli strain 364 and use of said strain as a vaccine (United States Patent 5,641,491)
Bacterial strain of Escherichia coli VNII genetika 472T23 as the producer of L-threonine (United States Patent 5,631,157)
Enzyme-capture assay (ECA) for the identification of Escherichia coli in clinical samples (United States Patent 5,612,186)
Escherichia coli containing a gene encoding a maltogenic amylase BLMA of Bacillus licheniformis and gene product produced by same (United States Patent 5,583,039)
Method and colicin composition for inhibiting Escherichia coli 0157:H7 in food products (United States Patent 5,549,895)
Bacterial strain of escherichia coli BKIIM B-3996 as the producer of l-threonine (United States Patent 5,538,873)
Production of isoleucine by escherichia coli having isoleucine auxotrophy and no negative feedback inhibition of isoleucine production (United States Patent 5,534,421)
Regulation of Escherichia coli and other microorganisms through magnetic water treatment (United States Patent 5,534,156)
Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-beta-hydroxybutyrate biosynthetic pathway (United States Patent 5,518,907)
Method for the improved production and recovery of poly-.beta.-hydroxybutyrate from transformed Escherichia coli (United States Patent 5,512,456)
Process for the production of L-threonine and L-isoleucine by fermentation of Escherichia coli (United States Patent 5,474,918)
Reverse transcriptases from Escherichia coli and Myxococcus xanthus (United States Patent 5,434,070)
Mutant Escherichia coli capable of enhanced L-glutamic acid production (United States Patent 5,393,671)
Test media for identifying and differentiating general coliforms and Escherichia coli bacteria (United States Patent 5,393,662)
Mutant Escherichia coli capable of enhanced L-glutamic acid production by fermentation (United States Patent 5,378,616)
Method for determining susceptibility to escherichia coli urinary tract infections and method for diagnosing secretors and nonsecretors (United States Patent 5,374,532)
Escherichia coliO-polysaccharide-protein conjugate vaccine (United States Patent 5,370,872)
Method, test media and chromogenic compounds for identifying and differentiating general coliforms and Escherichia coli bacteria (United States Patent 5,358,854)
Monoclonal antibody to enterohemorrhagic Escherichia coli 0157:H7 and 026:H11 and method for detection (United States Patent 5,354,661)
Production of poly-beta-hydroxybutyrate in transformed escherichia coli (United States Patent 5,334,520)
Process for producing foreign protein in Escherichia coli (United States Patent 5,304,471)
Cloned tyrosine phenol-lyase gene, recombinant plasmid containing the same and escherichia coli transformed with the same (United States Patent 5,260,198)
Method test media and chromogenic compounds for identifying and differentiating general coliforms and Escherichia coli bacteria (United States Patent 5,210,022)
Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.