Professor Demchick's Patent Services
Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)
Professor Demchick's Patent Services
Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)
PATENTS RELATED TO FLUORESCENCE MICROSCOPY Although it is not necessary for a patent agent to have personal experience with the specific subject matter, such personal experience has its advantages. Dr. Demchick has considerable microscopy experience including developing some new microscopy techniques. References include:
Dr. Demchick also has taught about microscopy in various college and university courses.P. Demchick and A.L. Koch. 1996. The permeability of the wall fabric of Escherichia coli and Bacillus subtilis. Journal of Bacteriology. 178:768-773.
S. Woeste and P.H. Demchick. 1991. New version of the negative stain. Applied and Environmental Microbiology. 57:1858-1859.
Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.
If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.
The following sampling is to give you some sense of the types of fluorescence microscopy related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.
It should be noted that spelling, form and typographical errors in the original patents are preserved here.
Dual axis fluorescence microscope with modulated input (United States Patent 7,130,042)
Superresolution in microlithography and fluorescence microscopy (United States Patent 7,071,477)
Eye protection system on an electronically controlled fluorescence microscope (United States Patent 7,067,825)
Fluorescence microscope (United States Patent 7,061,672)
Scanning microscopy, fluorescence detection, and laser beam positioning (United States Patent 7,050,208)
Fluorescence microscope (United States Patent 7,038,847)
Quantified fluorescence microscopy (United States Patent 6,984,828)
Immersion medium supply apparatus, fluorescence spectrometry inspection apparatus, and culture microscope (United States Patent 6,980,293)
Method for the detection of dyes in fluorescence microscopy (United States Patent 6,958,811)
Method and system for scanning apertureless fluorescence microscope (United States Patent 6,953,927)
Time resolved fluorescence microscope (United States Patent 6,914,720)
Epi-illumination apparatus for fluorescent observation and fluorescence microscope having the same (United States Patent 6,906,859)
Superresolution in microlithography and fluorescence microscopy (United States Patent 6,903,347)
Method for the detection of dyes in fluorescence microscopy (United States Patent 6,891,613)
Method and apparatus for rapid change of fluorescence bands in the detection of dyes in fluorescence microscopy (United States Patent 6,858,852)
Method for fluorescence microscopy, and fluorescence microscope (United States Patent 6,806,953)
Optical system in the ray path of a confocal fluorescence microscope (United States Patent 6,785,302)
Multiphoton excitation microscope for biochip fluorescence assay (United States Patent 6,768,122)
Total internal reflection fluorescence microscope having a conventional white-light source (United States Patent 6,751,018)
Method for the individual adaptation of excitation intensities in a multiband fluorescence microscope and multiband fluorescence microscope for carrying out said method (United States Patent 6,747,280)
Method for detecting fluorescence phenomena in microscope (United States Patent 6,741,346)
Method and apparatus for the detection of fluorescent light in confocal scanning microscopy (United States Patent 6,677,596)
Focusing system for a microscope and a reflected illumination fluorescence microscope using the focusing system (United States Patent 6,674,574)
Fluorescence digital imaging microscopy system (United States Patent 6,665,430)
Calibration of fluorescence resonance energy transfer in microscopy (United States Patent 6,661,909)
Total internal reflection fluorescence microscope having a conventional white-light source (United States Patent 6,597,499)
Microscope, especially a fluorescence microscope, particularly a stereo fluorescence microscope (United States Patent 6,563,113)
Apparatus for illuminating a specimen and confocal fluorescence scanning microscope (United States Patent 6,555,826)
Quantified fluorescence microscopy (United States Patent 6,472,671)
Fluorescence digital imaging microscopy system (United States Patent 6,459,805)
Calibration of fluorescence resonance energy transfer in microscopy (United States Patent 6,456,734)
Laser scanning fluorescence microscopy with compensation for spatial dispersion of fast laser pulses (United States Patent 6,449,039)
Reflected-light type fluorescence microscope and filter cassette used therefor (United States Patent 6,414,805)
Fiber-coupled, angled-dual-illumination-axis confocal scanning microscopes for performing reflective and two-photon fluorescence imaging (United States Patent 6,369,928)
Fluorescent microscope (United States Patent 6,262,837)
Objective lens unit for reflective fluorescence and reflective fluorescence microscope having an objective lens unit for reflective fluorescence (United States Patent 6,219,189)
Signal enhancement for fluorescence microscopy (United States Patent 6,169,289)
Semiconductor based excitation illuminator for fluorescence and phosphorescence microscopy (United States Patent 6,154,282)
Fluorescence stereo microscope illuminator (United States Patent 6,147,800)
Reflected fluorescence microscope with multiple laser and excitation light sources (United States Patent 6,075,643)
Reflecting fluorescence microscope (United States Patent 6,040,940)
Three-dimensional holographic fluorescence microscope (United States Patent 6,038,041)
Incident-light fluorescence microscope (United States Patent 6,025,956)
Scanning probe microscope using fluorescent light (United States Patent 5,986,256)
Pump probe cross correlation fluorescence frequency domain microscope and microscopy (United States Patent 5,814,820)
Arrangement for confocal fluorescence microscopy (United States Patent 5,751,417)
Objective lens system for fluorescence microscopes (United States Patent 5,739,957)
Reflecting fluorescence microscope (United States Patent 5,710,663)
Optical switching apparatus for a reflected fluorescence microscope (United States Patent 5,633,752)
Reflected fluorescence microscope (United States Patent 5,371,624)
Scanning confocal microscope using fluorescence detection (United States Patent 5,296,703)
Fluorescent confocal microscope with chromatic aberration compensation (United States Patent 5,296,700)
Method of making microscopic particles containing imbedded fluorescent dyes (United States Patent 5,229,041)
Microscopic particles containing imbedded fluorescent dyes and use thereof in particle-image velocimetry (United States Patent 5,124,071)
Near-field scanning optical microscope using a fluorescent probe (United States Patent 5,105,305)
Method of using an opaque plastic microscope slide for epi-fluorescent microscopy (United States Patent 5,095,213)
Laser excited confocal microscope fluorescence scanner and method (United States Patent 5,091,652)
Scanning tunneling microscope memory utilizing optical fluorescence of substrate for reading (United States Patent 5,051,977)
Device and method for fluorescence microscopic controlled formation of monomolecular layers of organic films (United States Patent 5,044,308)
Method of calibrating a flow cytometer or fluorescence microscope for quantitating binding antibodies on a selected sample, and microbead calibration kit therefor (United States Patent 4,918,004)
Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells (United States Patent 4,868,126)
Fluorescence microscopy (United States Patent 4,791,310)
Immersion oil composition having low fluorescence emissions for microscope (United States Patent 4,789,490)
Fluorescence microscopy sample mounting method and structure (United States Patent 4,689,307)
Immersion oil for fluorescence microscopy (United States Patent 4,491,533)
Apparatus for investigation of fluorescence characteristics of microscopic objects (United States Patent 4,354,114)
Illumination device for fluorescence microscopes (United States Patent 4,311,358)
Fluorescence determining microscope utilizing laser light (United States Patent 4,284,897)
Oil immersion liquid for fluorescence microscopes (United States Patent 4,108,794)
Illuminated system for vertical fluorescent microscopy (United States Patent 4,027,944)
Incident light fluorescence microscope (United States Patent 3,973,827)
Dual axis fluorescence microscope with modulated input (United States Patent 7,130,042)
Superresolution in microlithography and fluorescence microscopy (United States Patent 7,071,477)
Eye protection system on an electronically controlled fluorescence microscope (United States Patent 7,067,825)
Fluorescence microscope (United States Patent 7,061,672)
Scanning microscopy, fluorescence detection, and laser beam positioning (United States Patent 7,050,208)
Fluorescence microscope (United States Patent 7,038,847)
Quantified fluorescence microscopy (United States Patent 6,984,828)
Immersion medium supply apparatus, fluorescence spectrometry inspection apparatus, and culture microscope (United States Patent 6,980,293)
Method for the detection of dyes in fluorescence microscopy (United States Patent 6,958,811)
Method and system for scanning apertureless fluorescence microscope (United States Patent 6,953,927)
Time resolved fluorescence microscope (United States Patent 6,914,720)
Epi-illumination apparatus for fluorescent observation and fluorescence microscope having the same (United States Patent 6,906,859)
Superresolution in microlithography and fluorescence microscopy (United States Patent 6,903,347)
Method for the detection of dyes in fluorescence microscopy (United States Patent 6,891,613)
Method and apparatus for rapid change of fluorescence bands in the detection of dyes in fluorescence microscopy (United States Patent 6,858,852)
Method for fluorescence microscopy, and fluorescence microscope (United States Patent 6,806,953)
Optical system in the ray path of a confocal fluorescence microscope (United States Patent 6,785,302)
Multiphoton excitation microscope for biochip fluorescence assay (United States Patent 6,768,122)
Total internal reflection fluorescence microscope having a conventional white-light source (United States Patent 6,751,018)
Method for the individual adaptation of excitation intensities in a multiband fluorescence microscope and multiband fluorescence microscope for carrying out said method (United States Patent 6,747,280)
Method for detecting fluorescence phenomena in microscope (United States Patent 6,741,346)
Method and apparatus for the detection of fluorescent light in confocal scanning microscopy (United States Patent 6,677,596)
Focusing system for a microscope and a reflected illumination fluorescence microscope using the focusing system (United States Patent 6,674,574)
Fluorescence digital imaging microscopy system (United States Patent 6,665,430)
Calibration of fluorescence resonance energy transfer in microscopy (United States Patent 6,661,909)
Total internal reflection fluorescence microscope having a conventional white-light source (United States Patent 6,597,499)
Microscope, especially a fluorescence microscope, particularly a stereo fluorescence microscope (United States Patent 6,563,113)
Apparatus for illuminating a specimen and confocal fluorescence scanning microscope (United States Patent 6,555,826)
Quantified fluorescence microscopy (United States Patent 6,472,671)
Fluorescence digital imaging microscopy system (United States Patent 6,459,805)
Calibration of fluorescence resonance energy transfer in microscopy (United States Patent 6,456,734)
Laser scanning fluorescence microscopy with compensation for spatial dispersion of fast laser pulses (United States Patent 6,449,039)
Reflected-light type fluorescence microscope and filter cassette used therefor (United States Patent 6,414,805)
Fiber-coupled, angled-dual-illumination-axis confocal scanning microscopes for performing reflective and two-photon fluorescence imaging (United States Patent 6,369,928)
Fluorescent microscope (United States Patent 6,262,837)
Objective lens unit for reflective fluorescence and reflective fluorescence microscope having an objective lens unit for reflective fluorescence (United States Patent 6,219,189)
Signal enhancement for fluorescence microscopy (United States Patent 6,169,289)
Semiconductor based excitation illuminator for fluorescence and phosphorescence microscopy (United States Patent 6,154,282)
Fluorescence stereo microscope illuminator (United States Patent 6,147,800)
Reflected fluorescence microscope with multiple laser and excitation light sources (United States Patent 6,075,643)
Reflecting fluorescence microscope (United States Patent 6,040,940)
Three-dimensional holographic fluorescence microscope (United States Patent 6,038,041)
Incident-light fluorescence microscope (United States Patent 6,025,956)
Scanning probe microscope using fluorescent light (United States Patent 5,986,256)
Pump probe cross correlation fluorescence frequency domain microscope and microscopy (United States Patent 5,814,820)
Arrangement for confocal fluorescence microscopy (United States Patent 5,751,417)
Objective lens system for fluorescence microscopes (United States Patent 5,739,957)
Reflecting fluorescence microscope (United States Patent 5,710,663)
Optical switching apparatus for a reflected fluorescence microscope (United States Patent 5,633,752)
Reflected fluorescence microscope (United States Patent 5,371,624)
Scanning confocal microscope using fluorescence detection (United States Patent 5,296,703)
Fluorescent confocal microscope with chromatic aberration compensation (United States Patent 5,296,700)
Method of making microscopic particles containing imbedded fluorescent dyes (United States Patent 5,229,041)
Microscopic particles containing imbedded fluorescent dyes and use thereof in particle-image velocimetry (United States Patent 5,124,071)
Near-field scanning optical microscope using a fluorescent probe (United States Patent 5,105,305)
Method of using an opaque plastic microscope slide for epi-fluorescent microscopy (United States Patent 5,095,213)
Laser excited confocal microscope fluorescence scanner and method (United States Patent 5,091,652)
Scanning tunneling microscope memory utilizing optical fluorescence of substrate for reading (United States Patent 5,051,977)
Device and method for fluorescence microscopic controlled formation of monomolecular layers of organic films (United States Patent 5,044,308)
Method of calibrating a flow cytometer or fluorescence microscope for quantitating binding antibodies on a selected sample, and microbead calibration kit therefor (United States Patent 4,918,004)
Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells (United States Patent 4,868,126)
Fluorescence microscopy (United States Patent 4,791,310)
Immersion oil composition having low fluorescence emissions for microscope (United States Patent 4,789,490)
Fluorescence microscopy sample mounting method and structure (United States Patent 4,689,307)
Immersion oil for fluorescence microscopy (United States Patent 4,491,533)
Apparatus for investigation of fluorescence characteristics of microscopic objects (United States Patent 4,354,114)
Illumination device for fluorescence microscopes (United States Patent 4,311,358)
Fluorescence determining microscope utilizing laser light (United States Patent 4,284,897)
Oil immersion liquid for fluorescence microscopes (United States Patent 4,108,794)
Illuminated system for vertical fluorescent microscopy (United States Patent 4,027,944)
Incident light fluorescence microscope (United States Patent 3,973,827)
Dual axis fluorescence microscope with modulated input (United States Patent 7,130,042)
Superresolution in microlithography and fluorescence microscopy (United States Patent 7,071,477)
Eye protection system on an electronically controlled fluorescence microscope (United States Patent 7,067,825)
Fluorescence microscope (United States Patent 7,061,672)
Scanning microscopy, fluorescence detection, and laser beam positioning (United States Patent 7,050,208)
Fluorescence microscope (United States Patent 7,038,847)
Quantified fluorescence microscopy (United States Patent 6,984,828)
Immersion medium supply apparatus, fluorescence spectrometry inspection apparatus, and culture microscope (United States Patent 6,980,293)
Method for the detection of dyes in fluorescence microscopy (United States Patent 6,958,811)
Method and system for scanning apertureless fluorescence microscope (United States Patent 6,953,927)
Time resolved fluorescence microscope (United States Patent 6,914,720)
Epi-illumination apparatus for fluorescent observation and fluorescence microscope having the same (United States Patent 6,906,859)
Superresolution in microlithography and fluorescence microscopy (United States Patent 6,903,347)
Method for the detection of dyes in fluorescence microscopy (United States Patent 6,891,613)
Method and apparatus for rapid change of fluorescence bands in the detection of dyes in fluorescence microscopy (United States Patent 6,858,852)
Method for fluorescence microscopy, and fluorescence microscope (United States Patent 6,806,953)
Optical system in the ray path of a confocal fluorescence microscope (United States Patent 6,785,302)
Multiphoton excitation microscope for biochip fluorescence assay (United States Patent 6,768,122)
Total internal reflection fluorescence microscope having a conventional white-light source (United States Patent 6,751,018)
Method for the individual adaptation of excitation intensities in a multiband fluorescence microscope and multiband fluorescence microscope for carrying out said method (United States Patent 6,747,280)
Method for detecting fluorescence phenomena in microscope (United States Patent 6,741,346)
Method and apparatus for the detection of fluorescent light in confocal scanning microscopy (United States Patent 6,677,596)
Focusing system for a microscope and a reflected illumination fluorescence microscope using the focusing system (United States Patent 6,674,574)
Fluorescence digital imaging microscopy system (United States Patent 6,665,430)
Calibration of fluorescence resonance energy transfer in microscopy (United States Patent 6,661,909)
Total internal reflection fluorescence microscope having a conventional white-light source (United States Patent 6,597,499)
Microscope, especially a fluorescence microscope, particularly a stereo fluorescence microscope (United States Patent 6,563,113)
Apparatus for illuminating a specimen and confocal fluorescence scanning microscope (United States Patent 6,555,826)
Quantified fluorescence microscopy (United States Patent 6,472,671)
Fluorescence digital imaging microscopy system (United States Patent 6,459,805)
Calibration of fluorescence resonance energy transfer in microscopy (United States Patent 6,456,734)
Laser scanning fluorescence microscopy with compensation for spatial dispersion of fast laser pulses (United States Patent 6,449,039)
Reflected-light type fluorescence microscope and filter cassette used therefor (United States Patent 6,414,805)
Fiber-coupled, angled-dual-illumination-axis confocal scanning microscopes for performing reflective and two-photon fluorescence imaging (United States Patent 6,369,928)
Fluorescent microscope (United States Patent 6,262,837)
Objective lens unit for reflective fluorescence and reflective fluorescence microscope having an objective lens unit for reflective fluorescence (United States Patent 6,219,189)
Signal enhancement for fluorescence microscopy (United States Patent 6,169,289)
Semiconductor based excitation illuminator for fluorescence and phosphorescence microscopy (United States Patent 6,154,282)
Fluorescence stereo microscope illuminator (United States Patent 6,147,800)
Reflected fluorescence microscope with multiple laser and excitation light sources (United States Patent 6,075,643)
Reflecting fluorescence microscope (United States Patent 6,040,940)
Three-dimensional holographic fluorescence microscope (United States Patent 6,038,041)
Incident-light fluorescence microscope (United States Patent 6,025,956)
Scanning probe microscope using fluorescent light (United States Patent 5,986,256)
Pump probe cross correlation fluorescence frequency domain microscope and microscopy (United States Patent 5,814,820)
Arrangement for confocal fluorescence microscopy (United States Patent 5,751,417)
Objective lens system for fluorescence microscopes (United States Patent 5,739,957)
Reflecting fluorescence microscope (United States Patent 5,710,663)
Optical switching apparatus for a reflected fluorescence microscope (United States Patent 5,633,752)
Reflected fluorescence microscope (United States Patent 5,371,624)
Scanning confocal microscope using fluorescence detection (United States Patent 5,296,703)
Fluorescent confocal microscope with chromatic aberration compensation (United States Patent 5,296,700)
Method of making microscopic particles containing imbedded fluorescent dyes (United States Patent 5,229,041)
Microscopic particles containing imbedded fluorescent dyes and use thereof in particle-image velocimetry (United States Patent 5,124,071)
Near-field scanning optical microscope using a fluorescent probe (United States Patent 5,105,305)
Method of using an opaque plastic microscope slide for epi-fluorescent microscopy (United States Patent 5,095,213)
Laser excited confocal microscope fluorescence scanner and method (United States Patent 5,091,652)
Scanning tunneling microscope memory utilizing optical fluorescence of substrate for reading (United States Patent 5,051,977)
Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.