Professor Demchick's Patent Services

Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)


PATENTS RELATED TO GRAM POSITIVE BACTERIA

Although Dr. Demchick also represents patent seekers with non-microbiological inventions, his doctorate is in microbiology. Microbiology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving microbiology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of gram positive bacteria related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Antibacterial compounds and methods for treating Gram positive bacterial infections (United States Patent 7,144,858)

Promoters showing stationary phase-specific activity in gram-positive bacteria (United States Patent 7,125,690)

Proteases from gram positive organisms (United States Patent 7,098,021)

Proteases from gram positive organisms (United States Patent 7,078,372)

Proteases from gram positive organisms (United States Patent 7,078,216)

Proteases from GRAM positive organisms (United States Patent 7,070,990)

Proteases from gram positive organisms (United States Patent 7,070,986)

Proteases from gram positive organisms (United States Patent 7,070,819)

Method to produce a tampon that inhibits exoprotein production from gram positive bacteria (United States Patent 7,056,891)

Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same (United States Patent 7,037,714)

Proteases from gram positive organisms (United States Patent 7,033,817)

Aromatic compositions for the inhibition of exoprotein production from gram positive bacteria (United States Patent 7,026,354)

Inhibition of Gram positive bacteria (United States Patent 7,026,353)

Gram positive bacteria deprived of HtrA protease activity and their uses (United States Patent 6,994,997)

Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof (United States Patent 6,964,949)

Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria (United States Patent 6,939,543)

Polypeptides implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis (United States Patent 6,916,906)

Methods for the inhibition of exoprotein production from Gram positive bacteria (United States Patent 6,911,480)

Proteases from gram-positive organisms (United States Patent 6,911,333)

Proteases from gram-positive organisms (United States Patent 6,905,868)

Proteases from gram-positive organisms (United States Patent 6,881,562)

Proteases from gram positive organisms (United States Patent 6,872,807)

Proteases from gram-positive organisms (United States Patent 6,849,440)

Construction of a structural variant of sublancin to facilitate its isolation and use in bioremediation of environmental contamination by gram-positive spore formers such as bacillus anthrasis (United States Patent 6,846,804)

Proteases from gram-positive organisms (United States Patent 6,833,265)

Proteases from gram-positive organisms (United States Patent 6,833,261)

Gram-positive fatty acid degrader (United States Patent 6,818,211)

Proteases from gram positive organisms (United States Patent 6,794,179)

Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them (United States Patent 6,790,448)

Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria (United States Patent 6,737,521)

Proteases from gram-positive organisms (United States Patent 6,723,550)

Secretion factors for gram-positive micoorganisms, genes encoding them and methods of using it (United States Patent 6,692,951)

Non-absorbent substrates for the inhibition of exoprotein production from gram positive bacteria (United States Patent 6,676,957)

Inhibition of exoprotein production from gram positive bacteria (United States Patent 6,656,913)

Gram-positive fatty acid degrader (United States Patent 6,649,401)

Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof (United States Patent 6,632,796)

Increasing production of proteins in gram-positive microorganisms (United States Patent 6,630,328)

Antibacterial composition for control of gram positive bacteria in food applications (United States Patent 6,620,446)

Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria (United States Patent 6,610,293)

Proteases from gram positive organisms (United States Patent 6,599,731)

Absorbent articles for the inhibition of exoprotein production from Gram positive bacteria (United States Patent 6,599,521)

Nucleic acids encoding a protein conferring an inducible resistance to glycopeptide, particularly in gram-positive bacteria (United States Patent 6,569,622)

Treatment and diagnosis of infections of gram positive cocci (United States Patent 6,544,516)

Isoprenoid compositions for the inhibition of exoprotein production from gram positive bacteria (United States Patent 6,534,548)

Compositions for the inhibition of exoprotein production from Gram positive bacteria (United States Patent 6,531,435)

Proteases from gram positive organisms (United States Patent 6,528,255)

Proteases from gram-positive organisms (United States Patent 6,521,440)

Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same (United States Patent 6,521,421)

Increasing production of proteins in gram-positive microorganisms using SecG (United States Patent 6,506,579)

Proteases from gram positive organisms (United States Patent 6,489,108)

Antimicrobial wipes which provide improved residual benefit versus gram positive bacteria (United States Patent 6,482,423)

Proteases from gram positive organisms (United States Patent 6,465,186)

Enhancing growth in gram-positive microorganisms using formate supplementation and inactivation of formate-associated transport proteins (United States Patent 6,458,557)

Antibacterial composition for control of gram positive bacteria in food applications (United States Patent 6,451,365)

Method for promoting the growth of gram-positive bacilli and increasing the acidity in vagina (United States Patent 6,440,949)

Regulable gene expression in gram-positive bacteria (United States Patent 6,436,694)

Secretion factors for gram-positive microorganisms genes encoding them and methods of using it (United States Patent 6,410,262)

Compositions for treatment of antibiotic-resistant gram-positive bacterial infections and methods for using and preparing the same (United States Patent 6,316,033)

Proteases from gram-positive organisms (United States Patent 6,300,117)

Gram-positive alkaliphilic microorganisms (United States Patent 6,291,229)

Leave-on antimicrobial compositions which provide improved residual benefit versus gram positive bacteria (United States Patent 6,287,577)

Antimicrobial wipes which provide improved residual benefit versus Gram positive bacteria (United States Patent 6,284,259)

Type II phospholipase A2 and its use in killing Gram-positive bacteria (United States Patent 6,280,726)

Gram-positive bacterium transformed with a replicon (United States Patent 6,258,604)

Increasing production of proteins in gram-positive microorganisms (United States Patent 6,258,563)

Mild, rinse-off antimicrobial liquid cleansing compositions which provide improved residual benefit versus gram positive bacteria (United States Patent 6,190,675)

Use of antibodies to block the effects of gram-positive bacteria and mycobacteria (United States Patent 6,168,790)

Nucleic acids conferring and inducible resistance to glycopeptides particularly in gram-positive bacteria (United States Patent 6,087,106)

Anti-gram-positive bacterial methods and materials (United States Patent 6,054,431)

Compositions for treatment of antibiotic-resistant gram-positive bacterial infections and methods for using and preparing the same (United States Patent 6,025,400)

Polypeptides implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis (United States Patent 6,013,508)

Method for screening inhibitors of the enzyme which cleaves the anchor of surface proteins from gram positive bacteria (United States Patent 5,968,763)

Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria (United States Patent 5,945,278)

Expression of a gram-positive bacteria replicon (United States Patent 5,928,897)

Ethanol production in gram-positive microbes (United States Patent 5,916,787)

Method for killing gram positive bacteria with isolated type II phospholipase A2 (United States Patent 5,874,079)

Probes for the detection of nucleotide sequences implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria (United States Patent 5,871,910)

Method for the control of antibiotic-resistant gram positive bacteria and treatment of infection (United States Patent 5,866,539)

Gram-positive alkaliphilic microorganisms (United States Patent 5,858,748)

Secretion of outer membrane proteins of gram-negative bacteria by means of gram-positive host organisms (United States Patent 5,858,727)

Use of lactoferrin for therapy of acute of chronic infectious diseases by the intracellular gram-positive pathogens streptococcus pyogenes and staphylococcus aureus (United States Patent 5,834,424)

Use of gram-positive bacteria to express recombinant proteins (United States Patent 5,821,088)

Anti-gram-positive bacterial methods and materials (United States Patent 5,783,561)

Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria (United States Patent 5,780,261)

Protein conferring an inducible resistance to glycopeptides, particularly in gram-positive bacteria (United States Patent 5,770,361)

Gram-positive bacteria replicon (United States Patent 5,766,586)

Pharmaceutical agents for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria (United States Patent 5,750,535)

Gram-positive alkaliphilic microorganisms (United States Patent 5,707,851)

Method for treating gram positive septicemia (United States Patent 5,624,904)

Anti-gram-positive bacterial methods and materials (United States Patent 5,578,572)

Antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections (United States Patent 5,516,905)

Ethanol production in Gram-positive microbes (United States Patent 5,482,846)

Gram-positive alkaliphilic microorganisms (United States Patent 5,401,657)

Method for the conjugative transfer of mobilizable vectors for E. coli to gram-positive bacteria and vectors suitable for use in such a method (United States Patent 5,346,818)

DNA encoding polypeptides with activity against gram-positive and gram-negative bacteria (United States Patent 5,344,765)

Cecropin polypetides with activity against Gram-positive and Gram-negative bacteria (United States Patent 5,166,321)

Gram-positive and gram-negative antibacterial compounds from the microorganism, Janthinobacterium lividum (United States Patent 5,081,225)

Gram-positive expression control sequences (United States Patent 4,868,111)

Partition proficiency in genetically engineered plasmids for transforming gram-positive organisms (United States Patent 4,822,739)

Anti-gram positive bacteria tri-yne carbonates (United States Patent 4,806,566)

Antibacterial compounds and methods for treating Gram positive bacterial infections (United States Patent 7,144,858)

Promoters showing stationary phase-specific activity in gram-positive bacteria (United States Patent 7,125,690)

Proteases from gram positive organisms (United States Patent 7,098,021)

Proteases from gram positive organisms (United States Patent 7,078,372)

Proteases from gram positive organisms (United States Patent 7,078,216)

Proteases from GRAM positive organisms (United States Patent 7,070,990)

Proteases from gram positive organisms (United States Patent 7,070,986)

Proteases from gram positive organisms (United States Patent 7,070,819)

Method to produce a tampon that inhibits exoprotein production from gram positive bacteria (United States Patent 7,056,891)

Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same (United States Patent 7,037,714)

Proteases from gram positive organisms (United States Patent 7,033,817)

Aromatic compositions for the inhibition of exoprotein production from gram positive bacteria (United States Patent 7,026,354)

Inhibition of Gram positive bacteria (United States Patent 7,026,353)

Gram positive bacteria deprived of HtrA protease activity and their uses (United States Patent 6,994,997)

Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof (United States Patent 6,964,949)

Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria (United States Patent 6,939,543)

Polypeptides implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis (United States Patent 6,916,906)

Methods for the inhibition of exoprotein production from Gram positive bacteria (United States Patent 6,911,480)

Proteases from gram-positive organisms (United States Patent 6,911,333)

Proteases from gram-positive organisms (United States Patent 6,905,868)

Proteases from gram-positive organisms (United States Patent 6,881,562)

Proteases from gram positive organisms (United States Patent 6,872,807)

Proteases from gram-positive organisms (United States Patent 6,849,440)

Construction of a structural variant of sublancin to facilitate its isolation and use in bioremediation of environmental contamination by gram-positive spore formers such as bacillus anthrasis (United States Patent 6,846,804)

Proteases from gram-positive organisms (United States Patent 6,833,265)

Proteases from gram-positive organisms (United States Patent 6,833,261)

Gram-positive fatty acid degrader (United States Patent 6,818,211)

Proteases from gram positive organisms (United States Patent 6,794,179)

Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them (United States Patent 6,790,448)

Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria (United States Patent 6,737,521)

Proteases from gram-positive organisms (United States Patent 6,723,550)

Secretion factors for gram-positive micoorganisms, genes encoding them and methods of using it (United States Patent 6,692,951)

Non-absorbent substrates for the inhibition of exoprotein production from gram positive bacteria (United States Patent 6,676,957)

Inhibition of exoprotein production from gram positive bacteria (United States Patent 6,656,913)

Gram-positive fatty acid degrader (United States Patent 6,649,401)

Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof (United States Patent 6,632,796)

Increasing production of proteins in gram-positive microorganisms (United States Patent 6,630,328)

Antibacterial composition for control of gram positive bacteria in food applications (United States Patent 6,620,446)

Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria (United States Patent 6,610,293)

Proteases from gram positive organisms (United States Patent 6,599,731)

Absorbent articles for the inhibition of exoprotein production from Gram positive bacteria (United States Patent 6,599,521)

Nucleic acids encoding a protein conferring an inducible resistance to glycopeptide, particularly in gram-positive bacteria (United States Patent 6,569,622)

Treatment and diagnosis of infections of gram positive cocci (United States Patent 6,544,516)

Isoprenoid compositions for the inhibition of exoprotein production from gram positive bacteria (United States Patent 6,534,548)

Compositions for the inhibition of exoprotein production from Gram positive bacteria (United States Patent 6,531,435)

Proteases from gram positive organisms (United States Patent 6,528,255)

Proteases from gram-positive organisms (United States Patent 6,521,440)

Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same (United States Patent 6,521,421)

Increasing production of proteins in gram-positive microorganisms using SecG (United States Patent 6,506,579)

Proteases from gram positive organisms (United States Patent 6,489,108)

Antimicrobial wipes which provide improved residual benefit versus gram positive bacteria (United States Patent 6,482,423)

Proteases from gram positive organisms (United States Patent 6,465,186)

Enhancing growth in gram-positive microorganisms using formate supplementation and inactivation of formate-associated transport proteins (United States Patent 6,458,557)

Antibacterial composition for control of gram positive bacteria in food applications (United States Patent 6,451,365)

Method for promoting the growth of gram-positive bacilli and increasing the acidity in vagina (United States Patent 6,440,949)

Regulable gene expression in gram-positive bacteria (United States Patent 6,436,694)

Secretion factors for gram-positive microorganisms genes encoding them and methods of using it (United States Patent 6,410,262)

Compositions for treatment of antibiotic-resistant gram-positive bacterial infections and methods for using and preparing the same (United States Patent 6,316,033)

Proteases from gram-positive organisms (United States Patent 6,300,117)

Gram-positive alkaliphilic microorganisms (United States Patent 6,291,229)

Leave-on antimicrobial compositions which provide improved residual benefit versus gram positive bacteria (United States Patent 6,287,577)

Antimicrobial wipes which provide improved residual benefit versus Gram positive bacteria (United States Patent 6,284,259)

Type II phospholipase A2 and its use in killing Gram-positive bacteria (United States Patent 6,280,726)

Gram-positive bacterium transformed with a replicon (United States Patent 6,258,604)

Increasing production of proteins in gram-positive microorganisms (United States Patent 6,258,563)

Mild, rinse-off antimicrobial liquid cleansing compositions which provide improved residual benefit versus gram positive bacteria (United States Patent 6,190,675)

Use of antibodies to block the effects of gram-positive bacteria and mycobacteria (United States Patent 6,168,790)

Nucleic acids conferring and inducible resistance to glycopeptides particularly in gram-positive bacteria (United States Patent 6,087,106)

Anti-gram-positive bacterial methods and materials (United States Patent 6,054,431)

Compositions for treatment of antibiotic-resistant gram-positive bacterial infections and methods for using and preparing the same (United States Patent 6,025,400)

Polypeptides implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis (United States Patent 6,013,508)

Method for screening inhibitors of the enzyme which cleaves the anchor of surface proteins from gram positive bacteria (United States Patent 5,968,763)

Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria (United States Patent 5,945,278)

Expression of a gram-positive bacteria replicon (United States Patent 5,928,897)

Ethanol production in gram-positive microbes (United States Patent 5,916,787)

Method for killing gram positive bacteria with isolated type II phospholipase A2 (United States Patent 5,874,079)

Probes for the detection of nucleotide sequences implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria (United States Patent 5,871,910)

Method for the control of antibiotic-resistant gram positive bacteria and treatment of infection (United States Patent 5,866,539)

Gram-positive alkaliphilic microorganisms (United States Patent 5,858,748)

Secretion of outer membrane proteins of gram-negative bacteria by means of gram-positive host organisms (United States Patent 5,858,727)

Use of lactoferrin for therapy of acute of chronic infectious diseases by the intracellular gram-positive pathogens streptococcus pyogenes and staphylococcus aureus (United States Patent 5,834,424)

Use of gram-positive bacteria to express recombinant proteins (United States Patent 5,821,088)

Anti-gram-positive bacterial methods and materials (United States Patent 5,783,561)

Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria (United States Patent 5,780,261)

Protein conferring an inducible resistance to glycopeptides, particularly in gram-positive bacteria (United States Patent 5,770,361)

Gram-positive bacteria replicon (United States Patent 5,766,586)

Pharmaceutical agents for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria (United States Patent 5,750,535)

Gram-positive alkaliphilic microorganisms (United States Patent 5,707,851)

Method for treating gram positive septicemia (United States Patent 5,624,904)

Anti-gram-positive bacterial methods and materials (United States Patent 5,578,572)

Antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections (United States Patent 5,516,905)

Ethanol production in Gram-positive microbes (United States Patent 5,482,846)

Gram-positive alkaliphilic microorganisms (United States Patent 5,401,657)

Method for the conjugative transfer of mobilizable vectors for E. coli to gram-positive bacteria and vectors suitable for use in such a method (United States Patent 5,346,818)

DNA encoding polypeptides with activity against gram-positive and gram-negative bacteria (United States Patent 5,344,765)

Cecropin polypetides with activity against Gram-positive and Gram-negative bacteria (United States Patent 5,166,321)

Gram-positive and gram-negative antibacterial compounds from the microorganism, Janthinobacterium lividum (United States Patent 5,081,225)

Gram-positive expression control sequences (United States Patent 4,868,111)

Partition proficiency in genetically engineered plasmids for transforming gram-positive organisms (United States Patent 4,822,739)

Anti-gram positive bacteria tri-yne carbonates (United States Patent 4,806,566)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.