PATENTS RELATED TO HEPATITIS

Although Dr. Demchick also represents patent seekers with non-microbiological inventions, his doctorate is in microbiology. Microbiology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving microbiology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of hepatitis related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,151,105)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,148,226)

Complex of Hepatitis B virus polymerase with p11 and method for controlling movement of the complex in HepG2 cell (United States Patent 7,148,013)

Screening methods to identify agents that selectively inhibit hepatitis C virus replication (United States Patent 7,148,006)

Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof (United States Patent 7,144,712)

Hepatitis B virus surface antigen mutant and methods of detection thereof (United States Patent 7,141,242)

Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides (United States Patent 7,138,376)

Hepatitis C virus inhibitors (United States Patent 7,135,462)

Conserved motif of hepatitis C virus E2/NS1 region (United States Patent 7,135,185)

Hepatitis C virus inhibitors (United States Patent 7,132,504)

Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents (United States Patent 7,129,337)

Bicyclic carbohydrate compounds useful in the treatment of infections caused by Flaviviridae sp., such as hepatitis C and bovine viral diarrhea viruses (United States Patent 7,125,853)

Aza-peptide macrocyclic hepatitis C serine protease inhibitors (United States Patent 7,125,845)

Lactam inhibitors of Hepatitis C virus NS3 protease (United States Patent 7,122,627)

Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents (United States Patent 7,122,306)

Peptides and their use as inhibitors of hepatitis C virus ns3 protease (United States Patent 7,119,073)

Macrocyclic peptides active against the hepatitis C virus (United States Patent 7,119,072)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase (United States Patent 7,115,658)

Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection (United States Patent 7,115,578)

Cycloalkyl heterocycles for treating hepatitis C virus (United States Patent 7,112,601)

Hepatitis C viral antigen immunoassay detection systems (United States Patent 7,108,967)

CD4.sup.+ T-lymphocyte-specific Hepatitis C virus-epitopes (United States Patent 7,108,856)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 7,108,855)

Antibodies to hepatitis C virus asialoglycoproteins (United States Patent 7,105,303)

Mutant human hepatitis B viral strain and uses thereof (United States Patent 7,105,165)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 7,101,561)

Remedies for hepatitis C (United States Patent 7,101,551)

Recombinant hepatitis B surface antigen (United States Patent 7,098,309)

Conserved motif of hepatitis C virus E2/NS1 region (United States Patent 7,098,303)

Hepatitis C receptor protein CD81 (United States Patent 7,097,987)

3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections (United States Patent 7,094,770)

Nucleoside derivatives for treating hepatitis C virus infection (United States Patent 7,094,768)

Abin-mediated hepatitis protection (United States Patent 7,094,756)

Enterically transmitted non-A/non-B hepatitis viral agent and characteristic epitopes thereof (United States Patent 7,094,406)

HCV core protein binding agents for treatment of hepatitis C virus infection (United States Patent 7,094,401)

Hepatitis C inhibitor tri-peptides (United States Patent 7,091,184)

Genetic immunization with nonstructural proteins of hepatitis C virus (United States Patent 7,078,500)

Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines (United States Patent 7,070,790)

Inhibition of hepatitis B virus (HBV) replication by RNA interference (United States Patent 7,067,249)

Hepatitis B virus surface protein (United States Patent 7,067,247)

Adsorbent for eliminating hepatitis C virus, adsorber, and adsorption method (United States Patent 7,056,507)

Hepatitis C virus peptides and uses thereof (United States Patent 7,052,830)

Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins (United States Patent 7,052,696)

Hepatitis C virus inhibitors (United States Patent 7,041,698)

Vaccine-induced hepatitis B viral strain and uses thereof (United States Patent 7,038,035)

In vitro activity assay for human hepatitis B virus (HBV) DNA polymerase, and its use for screening for inhibitors of HBV DNA polymerase (United States Patent 7,037,682)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 7,026,457)

Hepatitis (United States Patent 7,026,137)

Hepatitis C virus codon optimized non-structural NS3/4A fusion gene (United States Patent 7,022,830)

Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection (United States Patent 7,022,323)

Polynucleotides for the detection and quantification of hepatitis B virus nucleic acids (United States Patent 7,015,317)

Peptides as NS3-serine protease inhibitors of hepatitis C virus (United States Patent 7,012,066)

Avian hepatitis E virus, vaccines and methods of protecting against avian hepatitis-splenomegaly syndrome and mammalian hepatitis E (United States Patent 7,005,130)

Hepatitis B virus vectors for gene therapy (United States Patent 7,001,760)

Hepatitis C virus inhibitors (United States Patent 6,995,174)

Compositions and methods for treatment of hepatitis C virus-associated diseases (United States Patent 6,995,146)

Hepatitis A vaccines (United States Patent 6,991,929)

Immunogenic Hepatitis C virus non-structural polypeptides (United States Patent 6,986,892)

Oligonucleotides specific for hepatitis B virus (United States Patent 6,984,729)

Composition for treatment of and method of monitoring hepatitis C virus using interferon-TAU (United States Patent 6,982,081)

Sid nucleic acids and polypeptides selected from a pathogenic strain of hepatitis C virus and applications thereof (United States Patent 6,977,144)

Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents (United States Patent 6,974,864)

R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease (United States Patent 6,964,979)

Hepatitis C virus non-structural NS3/4A fusion gene (United States Patent 6,960,569)

Self-replicating RNA molecule from hepatitis C virus (United States Patent 6,956,117)

Anti hepatitis C virus antibody and uses thereof (United States Patent 6,951,646)

Treatment of hepatitis C using hyperthermia (United States Patent 6,951,219)

.beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B (United States Patent 6,946,450)

Oligonucleotides and methods for detecting hepatitis C viral nucleic acids (United States Patent 6,946,245)

3'terminal sequence of hepatitis C virus genome and diagnostic and therapeutic uses thereof (United States Patent 6,943,246)

Hepatitis A virus nucleotide sequences, recombinant proteins and uses thereof (United States Patent 6,942,965)

Peptide inhibitors of hepatitis C virus NS3 protease (United States Patent 6,939,854)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 6,930,176)

Hepatitis C virus constructs characterized by high efficiency replication (United States Patent 6,930,095)

Monoclonal antibodies specific for the E2 glycoprotein of hepatitic C virus and their use in the diagnosis, treatment, and prevention of hepatitis C (United States Patent 6,924,362)

Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection (United States Patent 6,924,270)

Hepatitis B virus treatment (United States Patent 6,921,534)

Hepatitis C inhibitor compound (United States Patent 6,919,423)

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus (United States Patent 6,919,203)

Macrocyclic NS-3 serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties (United States Patent 6,914,122)

Methods and compositions for treating hepatitis C virus (United States Patent 6,914,054)

Methods and compositions for treating hepatitis B (United States Patent 6,913,914)

Method for detecting hepatitis C virus (United States Patent 6,913,887)

Diaryl peptides as NS3-serine protease inhibitors of hepatitis C virus (United States Patent 6,911,428)

Hepatitis C inhibitor peptide analogs (United States Patent 6,908,901)

Combined hepatitis B treatment (United States Patent 6,905,677)

Compounds as NS3-serine protease inhibitors of hepatitis C virus (United States Patent 6,894,072)

Hepatitis vaccines containing 3-O-deacylated monophoshoryl lipid A (United States Patent 6,893,644)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 6,890,737)

Freeze-dried hepatitis A attenuated live vaccine and its stabilizer (United States Patent 6,884,422)

Method of treating viral hepatitis by administration of liquid human .alpha.-interferon (United States Patent 6,884,411)

Hepatitis-C virus type 4, 5, and 6 (United States Patent 6,881,821)

Method for treating hepatitis (United States Patent 6,881,407)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 6,878,727)

Substituted cycloalkyl P1' hepatitis C virus inhibitors (United States Patent 6,878,722)

Hepatitis C virus inhibitors (United States Patent 6,872,805)

Synthetic antigens for the detection of antibodies to hepatitis C virus (United States Patent 6,872,520)

Full-length GB virus C (hepatitis G virus) RNA transcripts are infectious in primary CD4 positive T cells (United States Patent 6,870,043)

Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,151,105)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,148,226)

Complex of Hepatitis B virus polymerase with p11 and method for controlling movement of the complex in HepG2 cell (United States Patent 7,148,013)

Screening methods to identify agents that selectively inhibit hepatitis C virus replication (United States Patent 7,148,006)

Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof (United States Patent 7,144,712)

Hepatitis B virus surface antigen mutant and methods of detection thereof (United States Patent 7,141,242)

Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides (United States Patent 7,138,376)

Hepatitis C virus inhibitors (United States Patent 7,135,462)

Conserved motif of hepatitis C virus E2/NS1 region (United States Patent 7,135,185)

Hepatitis C virus inhibitors (United States Patent 7,132,504)

Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents (United States Patent 7,129,337)

Bicyclic carbohydrate compounds useful in the treatment of infections caused by Flaviviridae sp., such as hepatitis C and bovine viral diarrhea viruses (United States Patent 7,125,853)

Aza-peptide macrocyclic hepatitis C serine protease inhibitors (United States Patent 7,125,845)

Lactam inhibitors of Hepatitis C virus NS3 protease (United States Patent 7,122,627)

Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents (United States Patent 7,122,306)

Peptides and their use as inhibitors of hepatitis C virus ns3 protease (United States Patent 7,119,073)

Macrocyclic peptides active against the hepatitis C virus (United States Patent 7,119,072)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase (United States Patent 7,115,658)

Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection (United States Patent 7,115,578)

Cycloalkyl heterocycles for treating hepatitis C virus (United States Patent 7,112,601)

Hepatitis C viral antigen immunoassay detection systems (United States Patent 7,108,967)

CD4.sup.+ T-lymphocyte-specific Hepatitis C virus-epitopes (United States Patent 7,108,856)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 7,108,855)

Antibodies to hepatitis C virus asialoglycoproteins (United States Patent 7,105,303)

Mutant human hepatitis B viral strain and uses thereof (United States Patent 7,105,165)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 7,101,561)

Remedies for hepatitis C (United States Patent 7,101,551)

Recombinant hepatitis B surface antigen (United States Patent 7,098,309)

Conserved motif of hepatitis C virus E2/NS1 region (United States Patent 7,098,303)

Hepatitis C receptor protein CD81 (United States Patent 7,097,987)

3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections (United States Patent 7,094,770)

Nucleoside derivatives for treating hepatitis C virus infection (United States Patent 7,094,768)

Abin-mediated hepatitis protection (United States Patent 7,094,756)

Enterically transmitted non-A/non-B hepatitis viral agent and characteristic epitopes thereof (United States Patent 7,094,406)

HCV core protein binding agents for treatment of hepatitis C virus infection (United States Patent 7,094,401)

Hepatitis C inhibitor tri-peptides (United States Patent 7,091,184)

Genetic immunization with nonstructural proteins of hepatitis C virus (United States Patent 7,078,500)

Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines (United States Patent 7,070,790)

Inhibition of hepatitis B virus (HBV) replication by RNA interference (United States Patent 7,067,249)

Hepatitis B virus surface protein (United States Patent 7,067,247)

Adsorbent for eliminating hepatitis C virus, adsorber, and adsorption method (United States Patent 7,056,507)

Hepatitis C virus peptides and uses thereof (United States Patent 7,052,830)

Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins (United States Patent 7,052,696)

Hepatitis C virus inhibitors (United States Patent 7,041,698)

Vaccine-induced hepatitis B viral strain and uses thereof (United States Patent 7,038,035)

In vitro activity assay for human hepatitis B virus (HBV) DNA polymerase, and its use for screening for inhibitors of HBV DNA polymerase (United States Patent 7,037,682)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 7,026,457)

Hepatitis (United States Patent 7,026,137)

Hepatitis C virus codon optimized non-structural NS3/4A fusion gene (United States Patent 7,022,830)

Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection (United States Patent 7,022,323)

Polynucleotides for the detection and quantification of hepatitis B virus nucleic acids (United States Patent 7,015,317)

Peptides as NS3-serine protease inhibitors of hepatitis C virus (United States Patent 7,012,066)

Avian hepatitis E virus, vaccines and methods of protecting against avian hepatitis-splenomegaly syndrome and mammalian hepatitis E (United States Patent 7,005,130)

Hepatitis B virus vectors for gene therapy (United States Patent 7,001,760)

Hepatitis C virus inhibitors (United States Patent 6,995,174)

Compositions and methods for treatment of hepatitis C virus-associated diseases (United States Patent 6,995,146)

Hepatitis A vaccines (United States Patent 6,991,929)

Immunogenic Hepatitis C virus non-structural polypeptides (United States Patent 6,986,892)

Oligonucleotides specific for hepatitis B virus (United States Patent 6,984,729)

Composition for treatment of and method of monitoring hepatitis C virus using interferon-TAU (United States Patent 6,982,081)

Sid nucleic acids and polypeptides selected from a pathogenic strain of hepatitis C virus and applications thereof (United States Patent 6,977,144)

Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents (United States Patent 6,974,864)

R-enantiomers of pyranoindole derivatives and the use thereof for the treatment of hepatitis C virus infection or disease (United States Patent 6,964,979)

Hepatitis C virus non-structural NS3/4A fusion gene (United States Patent 6,960,569)

Self-replicating RNA molecule from hepatitis C virus (United States Patent 6,956,117)

Anti hepatitis C virus antibody and uses thereof (United States Patent 6,951,646)

Treatment of hepatitis C using hyperthermia (United States Patent 6,951,219)

.beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B (United States Patent 6,946,450)

Oligonucleotides and methods for detecting hepatitis C viral nucleic acids (United States Patent 6,946,245)

3'terminal sequence of hepatitis C virus genome and diagnostic and therapeutic uses thereof (United States Patent 6,943,246)

Hepatitis A virus nucleotide sequences, recombinant proteins and uses thereof (United States Patent 6,942,965)

Peptide inhibitors of hepatitis C virus NS3 protease (United States Patent 6,939,854)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 6,930,176)

Hepatitis C virus constructs characterized by high efficiency replication (United States Patent 6,930,095)

Monoclonal antibodies specific for the E2 glycoprotein of hepatitic C virus and their use in the diagnosis, treatment, and prevention of hepatitis C (United States Patent 6,924,362)

Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection (United States Patent 6,924,270)

Hepatitis B virus treatment (United States Patent 6,921,534)

Hepatitis C inhibitor compound (United States Patent 6,919,423)

Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus (United States Patent 6,919,203)

Macrocyclic NS-3 serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties (United States Patent 6,914,122)

Methods and compositions for treating hepatitis C virus (United States Patent 6,914,054)

Methods and compositions for treating hepatitis B (United States Patent 6,913,914)

Method for detecting hepatitis C virus (United States Patent 6,913,887)

Diaryl peptides as NS3-serine protease inhibitors of hepatitis C virus (United States Patent 6,911,428)

Hepatitis C inhibitor peptide analogs (United States Patent 6,908,901)

Combined hepatitis B treatment (United States Patent 6,905,677)

Compounds as NS3-serine protease inhibitors of hepatitis C virus (United States Patent 6,894,072)

Hepatitis vaccines containing 3-O-deacylated monophoshoryl lipid A (United States Patent 6,893,644)

Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use (United States Patent 6,890,737)

Freeze-dried hepatitis A attenuated live vaccine and its stabilizer (United States Patent 6,884,422)

Method of treating viral hepatitis by administration of liquid human .alpha.-interferon (United States Patent 6,884,411)

Hepatitis-C virus type 4, 5, and 6 (United States Patent 6,881,821)

Method for treating hepatitis (United States Patent 6,881,407)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 6,878,727)

Substituted cycloalkyl P1' hepatitis C virus inhibitors (United States Patent 6,878,722)

Hepatitis C virus inhibitors (United States Patent 6,872,805)

Synthetic antigens for the detection of antibodies to hepatitis C virus (United States Patent 6,872,520)

Full-length GB virus C (hepatitis G virus) RNA transcripts are infectious in primary CD4 positive T cells (United States Patent 6,870,043)

Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,151,105)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.