PATENTS RELATED TO HYBRIDOMAS

Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of hybridomas related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Method of rapid production of hybridomas expressing monoclonal antibodies on the cell surface (United States Patent 7,148,040)

Hybridoma, an antibody resistant to an interfering substance, and a kit for immunological analysis (United States Patent 7,138,241)

Monoclonal antibody, its immunoreactive fragment and hybridoma (United States Patent 7,067,314)

Anti-APO-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring APO-B-48 using the same (United States Patent 7,052,855)

Anti-dioxins monoclonal antibody suitable for assaying dioxins in environment and hybridoma producing the same (United States Patent 7,038,021)

PEPTIDES AND POLYPEPTIDES DERIVED FROM THE SUBMAXILLARY GLAND OF THE RAT CORRESPONDING POLYCLONAL AND MONOCLONAL ANTIBODIES CORRESPONDING HYBRIDOMAS AND USES OF THESE PRODUCTS FOR DIAGNOSIS FOR DETECTION OR THERAPEUTIC PURPOSES (United States Patent 6,916,607)

Monoclonal antibody hybridoma immunoassay method and diagnosis kit (United States Patent 6,849,419)

Monoclonal antibodies for the detection of decoy receptor 3, hybridomas producing said antibodies and uses thereof (United States Patent 6,843,990)

Type I angiotensin II receptor specific monoclonal antibodies and hybridomas (United States Patent 6,805,864)

Method of isolating CD8+ cells, and related hybridoma cells antibodies and polypeptides (United States Patent 6,790,662)

Antibodies against phoshorylated VASP (vasodilator-stimulated phosphoprotein), hybridoma cells for their preparation, and their use (United States Patent 6,649,421)

Hybridomas and monoclonal antibodies for an anticoagulant test (United States Patent 6,538,112)

Antihuman thymidylate synthase monoclonal antibodies and hybridomas producing the same (United States Patent 6,500,932)

Method for the diagnosis of brain/neurological disease using monoclonal antibodies specific for PHF-tau, hybridomas secreting them, and antigen recognition by these antibodies and their applications (United States Patent 6,500,674)

Monoclonal antibody specific to anti-human fibrin monomer, process for producing the same, hybridomas, and immunoassay method (United States Patent 6,451,545)

Use of CD40 ligand, a cytokine that binds CD40, to stimulate hybridoma cells (United States Patent 6,391,637)

Hybridoma cell line and monoclonal antibody for huntingtin protein (United States Patent 6,355,481)

Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same (United States Patent 6,309,844)

Hybridoma and anti-KC-4 humanized monoclonal antibody (United States Patent 6,281,335)

Anti-CEA antibody designated 806.077, hybridoma and method of manufacture (United States Patent 6,277,599)

PSCA antibodies and hybridomas producing them (United States Patent 6,258,939)

Antibodies, production method of the antibodies, hybridomas which produce the antibodies, production method the hybirdomas and antigen proteins recognized by the antibodies (United States Patent 6,258,564)

Antibodies, production method of the antibodies, hybridomas which produce the antibodies, production method of the hybridomas and antigen proteins recognized by the antibodies (United States Patent 6,255,107)

Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these antibodies (United States Patent 6,252,052)

Monoclonal antibody which binds to a human-Th2-specific protein and hybridoma (United States Patent 6,166,186)

Hybridomas for lung cancer marker and monoclonal antibodies thereof (United States Patent 6,117,981)

Hybridoma cell lines producing monoclonal antibodies that bind to human plasma hyaluronidase (United States Patent 6,103,525)

Antibodies which specifically bind to a novel .kappa./.mu.-like protein tyrosineospatase, PTP.lambda., and hybridoma cell lines producing the same (United States Patent 6,083,748)

Type I angiotensin II receptor specific monoclonal antibodies and hybridomas (United States Patent 6,063,620)

Hybridomas and monoclonal antibodies that specifically bind to glutamic acid decarboxylase peptides (United States Patent 6,011,139)

Monoclonal antibodies specific for PHF-tau, hybridomas secreting them, antigen recognition by these antibodies and their applications (United States Patent 6,008,024)

MN-specific antibodies and hybridomas (United States Patent 5,981,711)

Monoclonal antibody, hybridoma, their production and use thereof (United States Patent 5,981,197)

Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same (United States Patent 5,961,974)

Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody (United States Patent 5,948,893)

Monoclonal antibodies against human interleukin-4 and hybridomas producing the same (United States Patent 5,912,136)

Anti-human plasmin-.alpha..sub.2 -plasmin inhibitor complex antibodies, hybridomas, and immunological determination method (United States Patent 5,888,749)

Immunassay of non-A, non-B hepatitis virus-related antigens, monoclonal antibodies for use therein, and hybridomas producing the antibodies (United States Patent 5,871,904)

Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications (United States Patent 5,861,257)

Peptides and polypeptides derived from the submaxillary gland of the rat, corresponding polyclonal and monoclonal antibodies, corresponding hybridomas and uses of these products for diagnosis, for detection or therapeutic purposes (United States Patent 5,859,189)

Monoclonal antibody, hybridoma, their production and use thereof (United States Patent 5,858,779)

Hybridomas producing antibodies specific for lyme disease antigens OspA and OspB (United States Patent 5,856,447)

Hybridomas producing monoclonal antibodies to new mucin epitopes (United States Patent 5,849,876)

Thymidine kinase-lacking ouabain-resistant chicken hybridoma (United States Patent 5,849,539)

Monoclonal antibodies directed against the microtubule-associated protein tau, and hybridomas secreting these antibodies (United States Patent 5,843,779)

Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications (United States Patent 5,843,676)

Hybridoma producing a monoclonal antibody for N-peptide (United States Patent 5,827,674)

Hybridoma cell lines and antibodies that bind noggin (United States Patent 5,821,124)

Anti-human soluble fibrin antibody, hybridoma, and immunoassaying method (United States Patent 5,821,068)

Monoclonal antibodies specific for HIV and the hybridomas for production thereof (United States Patent 5,783,670)

Anti-LAM 1-3 antibody and hybridoma (United States Patent 5,776,775)

Anti-ICAM-4 antibodies and hybridomas (United States Patent 5,773,293)

Hybridoma for producing antibody for collagen I (United States Patent 5,763,272)

Anti-sulfated tyrosine antibody specific for sulfated tyrosine, process for producing the same, and hybridoma capable of producing anti-sulfated tyrosine monoclonal antibody specific for sulfated tyrosine (United States Patent 5,716,836)

Monoclonal antibody to human glicentin, hybridoma for producing said antibody and assay method for human glicentin using said antibody (United States Patent 5,712,105)

Monoclonal antibodies specific for HIV and the hybridomas for production thereof (United States Patent 5,695,927)

Method of immunological assaying human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it (United States Patent 5,681,707)

Immortalized rabbit hybridoma fusion partner (United States Patent 5,675,063)

Production of monoclonal antibodies to bacteroides gingivalis by hybridoma BGII, VF9/2D (United States Patent 5,665,559)

Hybridomas producing bluetongue virus-specific monoclonals (United States Patent 5,652,134)

Assay and treatment for demyelinating diseases such as multiple sclerosis, related hybridomas and monoclonal antibodies (United States Patent 5,645,997)

Anti-thymosin .alpha.1 monoclonal antibody-producing hybridoma (United States Patent 5,643,735)

Monoclonal antibodies against Mycoplasma pneumoniae, hybridomas producing these, methods for the preparation thereof, and the use thereof (United States Patent 5,641,638)

Hybridomas producing antibodies to cardiac hypertrophy factor (United States Patent 5,627,073)

IL-6 specific monoclonal antibodies, hybridomas therefor and methods of making and using same (United States Patent 5,618,700)

Methods for the preparation of hybridomas producing lymphadenopathy-associated virus (LAV) GP110-specific monoclonal antibodies and methods for the purification of GP110 employing said monoclonal antibodies (United States Patent 5,610,035)

Murine hybridoma 4A11 and diagnostic antibody produced thereby (United States Patent 5,604,126)

Cell line TriH8 obtained by the fusion of the human epidermoid carcinoma cell line A431 with the TOS/H8 hybridoma (United States Patent 5,602,027)

Cadherin-specific antibodies and hybridoma cell lines (United States Patent 5,597,725)

Hybridoma and monoclonal antibody 9H10-A4 specific to an antigen of LNCaP cells (United States Patent 5,578,484)

Hybridoma cell lines which produce monoclonal antibodies having the properties of monoclonal antibody 100-310 and the monoclonal antibodies produced by these hybridoma cell lines (United States Patent 5,565,356)

Suppressor T-cell hybridoma and production of allergen specific glycosylation inhibiting factor (United States Patent 5,565,338)

Hybridoma-producing NSO myeloma cell line (United States Patent 5,565,337)

Hybridoma cell lines and their monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (United States Patent 5,552,286)

Hybridomas and monoclonal antibodies specific for unique determinants of nephropathy-related immunoglobulin G and complexes thereof (United States Patent 5,534,431)

Monoclonal IgA antibody specific for respiratory syncytial virus, a hybridoma cell line that produces this antibody amd methods of using the antibody to diagnose RSV infection (United States Patent 5,534,411)

Anti-idiotypic monoclonal antibody that induces an immune response against the ganglioside GD.sub.3 and hybridoma producing said antibody (United States Patent 5,529,922)

Immunoassay, monoclonal antibody, and hybridoma (United States Patent 5,525,476)

Production of monoclonal antibodies to Treponema denticola by hybridoma TDII, IAA11 (United States Patent 5,514,553)

Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it (United States Patent 5,506,111)

Hybridoma producing monoclonal antibody F4 which specifically binds to multidrug resistant P-glycoprotein and assays for detection of P-glycoprotein (United States Patent 5,503,984)

Hybridomas producing monoclonal antibodies specific for C-reactive protein and methods for detection of C-reactive protein (United States Patent 5,500,345)

Hybridoma and monoclonal antibody specific for human stem cell factor receptor and methods of use of the monoclonal antibody for detection of stem cell factor receptors (United States Patent 5,489,516)

Human anti-RH(D) monoclonal antibodies reagents and hybridomas and methods of RH typing using anti-RH(D) monoclonal antibodies and reagents (United States Patent 5,487,891)

Hybridomas and monoclonal antibodies that speifically bind to GPIB on platelets and inhibit the binding of thrombin to platelets (United States Patent 5,486,361)

Hybridomas and monoclonal antibodies which specifically bind human basic fibroblast growth factor (United States Patent 5,478,740)

Apolipoprotein B-specific monoclonal antibodies produced by two novel hybridomas (United States Patent 5,460,947)

Hybridomas producing monoclonal antibodies which specifically bind to continuous epitope on the human EGF receptor and compete with EGF for binding to the EGF receptor (United States Patent 5,459,061)

Hybridoma CT43 producing a monoclonal antibody to a novel mucin epitope which correlates with the presence of colorectal cancer (United States Patent 5,459,043)

Monoclonal antibodies specific for HIV and hybridomas for their production (United States Patent 5,445,960)

Monoclonal antibody against an acidic FGF protein and hybridoma for its production (United States Patent 5,437,995)

Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for assay of the inhibitors (United States Patent 5,422,245)

Chicken-specific immunoglobulin G-producing hybridoma (United States Patent 5,411,881)

Monoclonal antibodies to GP110 of HIV and hybridomas secreting these antibodies (United States Patent 5,407,811)

Class I MHC-restricted T-T hybridomas, and a CD8-transfected BW5147, fusion partner therefor (United States Patent 5,348,878)

Apolipoprotein B-specific monoclonal antibodies produced by two novel hybridomas (United States Patent 5,330,910)

Hybridoma producing a monoclonal antibody specific for an antigen of the stratum corneum of human epidermis (United States Patent 5,312,751)

Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide (United States Patent 5,300,434)

Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus (United States Patent 5,298,419)

Human-human hybridomas for neoplasms (United States Patent 5,286,647)

Method of rapid production of hybridomas expressing monoclonal antibodies on the cell surface (United States Patent 7,148,040)

Hybridoma, an antibody resistant to an interfering substance, and a kit for immunological analysis (United States Patent 7,138,241)

Monoclonal antibody, its immunoreactive fragment and hybridoma (United States Patent 7,067,314)

Anti-APO-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring APO-B-48 using the same (United States Patent 7,052,855)

Anti-dioxins monoclonal antibody suitable for assaying dioxins in environment and hybridoma producing the same (United States Patent 7,038,021)

PEPTIDES AND POLYPEPTIDES DERIVED FROM THE SUBMAXILLARY GLAND OF THE RAT CORRESPONDING POLYCLONAL AND MONOCLONAL ANTIBODIES CORRESPONDING HYBRIDOMAS AND USES OF THESE PRODUCTS FOR DIAGNOSIS FOR DETECTION OR THERAPEUTIC PURPOSES (United States Patent 6,916,607)

Monoclonal antibody hybridoma immunoassay method and diagnosis kit (United States Patent 6,849,419)

Monoclonal antibodies for the detection of decoy receptor 3, hybridomas producing said antibodies and uses thereof (United States Patent 6,843,990)

Type I angiotensin II receptor specific monoclonal antibodies and hybridomas (United States Patent 6,805,864)

Method of isolating CD8+ cells, and related hybridoma cells antibodies and polypeptides (United States Patent 6,790,662)

Antibodies against phoshorylated VASP (vasodilator-stimulated phosphoprotein), hybridoma cells for their preparation, and their use (United States Patent 6,649,421)

Hybridomas and monoclonal antibodies for an anticoagulant test (United States Patent 6,538,112)

Antihuman thymidylate synthase monoclonal antibodies and hybridomas producing the same (United States Patent 6,500,932)

Method for the diagnosis of brain/neurological disease using monoclonal antibodies specific for PHF-tau, hybridomas secreting them, and antigen recognition by these antibodies and their applications (United States Patent 6,500,674)

Monoclonal antibody specific to anti-human fibrin monomer, process for producing the same, hybridomas, and immunoassay method (United States Patent 6,451,545)

Use of CD40 ligand, a cytokine that binds CD40, to stimulate hybridoma cells (United States Patent 6,391,637)

Hybridoma cell line and monoclonal antibody for huntingtin protein (United States Patent 6,355,481)

Anti-apo-B-48 monoclonal antibody, hybridoma producing the same, and method for measuring apo-B-48 using the same (United States Patent 6,309,844)

Hybridoma and anti-KC-4 humanized monoclonal antibody (United States Patent 6,281,335)

Anti-CEA antibody designated 806.077, hybridoma and method of manufacture (United States Patent 6,277,599)

PSCA antibodies and hybridomas producing them (United States Patent 6,258,939)

Antibodies, production method of the antibodies, hybridomas which produce the antibodies, production method the hybirdomas and antigen proteins recognized by the antibodies (United States Patent 6,258,564)

Antibodies, production method of the antibodies, hybridomas which produce the antibodies, production method of the hybridomas and antigen proteins recognized by the antibodies (United States Patent 6,255,107)

Antibodies which bind to NY-ESO-1 cancer associated proteins, and hybridomas which produce these antibodies (United States Patent 6,252,052)

Monoclonal antibody which binds to a human-Th2-specific protein and hybridoma (United States Patent 6,166,186)

Hybridomas for lung cancer marker and monoclonal antibodies thereof (United States Patent 6,117,981)

Hybridoma cell lines producing monoclonal antibodies that bind to human plasma hyaluronidase (United States Patent 6,103,525)

Antibodies which specifically bind to a novel .kappa./.mu.-like protein tyrosineospatase, PTP.lambda., and hybridoma cell lines producing the same (United States Patent 6,083,748)

Type I angiotensin II receptor specific monoclonal antibodies and hybridomas (United States Patent 6,063,620)

Hybridomas and monoclonal antibodies that specifically bind to glutamic acid decarboxylase peptides (United States Patent 6,011,139)

Monoclonal antibodies specific for PHF-tau, hybridomas secreting them, antigen recognition by these antibodies and their applications (United States Patent 6,008,024)

MN-specific antibodies and hybridomas (United States Patent 5,981,711)

Monoclonal antibody, hybridoma, their production and use thereof (United States Patent 5,981,197)

Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same (United States Patent 5,961,974)

Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody (United States Patent 5,948,893)

Monoclonal antibodies against human interleukin-4 and hybridomas producing the same (United States Patent 5,912,136)

Anti-human plasmin-.alpha..sub.2 -plasmin inhibitor complex antibodies, hybridomas, and immunological determination method (United States Patent 5,888,749)

Immunassay of non-A, non-B hepatitis virus-related antigens, monoclonal antibodies for use therein, and hybridomas producing the antibodies (United States Patent 5,871,904)

Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications (United States Patent 5,861,257)

Peptides and polypeptides derived from the submaxillary gland of the rat, corresponding polyclonal and monoclonal antibodies, corresponding hybridomas and uses of these products for diagnosis, for detection or therapeutic purposes (United States Patent 5,859,189)

Monoclonal antibody, hybridoma, their production and use thereof (United States Patent 5,858,779)

Hybridomas producing antibodies specific for lyme disease antigens OspA and OspB (United States Patent 5,856,447)

Hybridomas producing monoclonal antibodies to new mucin epitopes (United States Patent 5,849,876)

Thymidine kinase-lacking ouabain-resistant chicken hybridoma (United States Patent 5,849,539)

Monoclonal antibodies directed against the microtubule-associated protein tau, and hybridomas secreting these antibodies (United States Patent 5,843,779)

Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications (United States Patent 5,843,676)

Hybridoma producing a monoclonal antibody for N-peptide (United States Patent 5,827,674)

Hybridoma cell lines and antibodies that bind noggin (United States Patent 5,821,124)

Anti-human soluble fibrin antibody, hybridoma, and immunoassaying method (United States Patent 5,821,068)

Monoclonal antibodies specific for HIV and the hybridomas for production thereof (United States Patent 5,783,670)

Anti-LAM 1-3 antibody and hybridoma (United States Patent 5,776,775)

Anti-ICAM-4 antibodies and hybridomas (United States Patent 5,773,293)

Hybridoma for producing antibody for collagen I (United States Patent 5,763,272)

Anti-sulfated tyrosine antibody specific for sulfated tyrosine, process for producing the same, and hybridoma capable of producing anti-sulfated tyrosine monoclonal antibody specific for sulfated tyrosine (United States Patent 5,716,836)

Monoclonal antibody to human glicentin, hybridoma for producing said antibody and assay method for human glicentin using said antibody (United States Patent 5,712,105)

Monoclonal antibodies specific for HIV and the hybridomas for production thereof (United States Patent 5,695,927)

Method of immunological assaying human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it (United States Patent 5,681,707)

Immortalized rabbit hybridoma fusion partner (United States Patent 5,675,063)

Production of monoclonal antibodies to bacteroides gingivalis by hybridoma BGII, VF9/2D (United States Patent 5,665,559)

Hybridomas producing bluetongue virus-specific monoclonals (United States Patent 5,652,134)

Assay and treatment for demyelinating diseases such as multiple sclerosis, related hybridomas and monoclonal antibodies (United States Patent 5,645,997)

Anti-thymosin .alpha.1 monoclonal antibody-producing hybridoma (United States Patent 5,643,735)

Monoclonal antibodies against Mycoplasma pneumoniae, hybridomas producing these, methods for the preparation thereof, and the use thereof (United States Patent 5,641,638)

Hybridomas producing antibodies to cardiac hypertrophy factor (United States Patent 5,627,073)

IL-6 specific monoclonal antibodies, hybridomas therefor and methods of making and using same (United States Patent 5,618,700)

Methods for the preparation of hybridomas producing lymphadenopathy-associated virus (LAV) GP110-specific monoclonal antibodies and methods for the purification of GP110 employing said monoclonal antibodies (United States Patent 5,610,035)

Murine hybridoma 4A11 and diagnostic antibody produced thereby (United States Patent 5,604,126)

Cell line TriH8 obtained by the fusion of the human epidermoid carcinoma cell line A431 with the TOS/H8 hybridoma (United States Patent 5,602,027)

Cadherin-specific antibodies and hybridoma cell lines (United States Patent 5,597,725)

Hybridoma and monoclonal antibody 9H10-A4 specific to an antigen of LNCaP cells (United States Patent 5,578,484)

Hybridoma cell lines which produce monoclonal antibodies having the properties of monoclonal antibody 100-310 and the monoclonal antibodies produced by these hybridoma cell lines (United States Patent 5,565,356)

Suppressor T-cell hybridoma and production of allergen specific glycosylation inhibiting factor (United States Patent 5,565,338)

Hybridoma-producing NSO myeloma cell line (United States Patent 5,565,337)

Hybridoma cell lines and their monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (United States Patent 5,552,286)

Hybridomas and monoclonal antibodies specific for unique determinants of nephropathy-related immunoglobulin G and complexes thereof (United States Patent 5,534,431)

Monoclonal IgA antibody specific for respiratory syncytial virus, a hybridoma cell line that produces this antibody amd methods of using the antibody to diagnose RSV infection (United States Patent 5,534,411)

Anti-idiotypic monoclonal antibody that induces an immune response against the ganglioside GD.sub.3 and hybridoma producing said antibody (United States Patent 5,529,922)

Immunoassay, monoclonal antibody, and hybridoma (United States Patent 5,525,476)

Production of monoclonal antibodies to Treponema denticola by hybridoma TDII, IAA11 (United States Patent 5,514,553)

Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it (United States Patent 5,506,111)

Hybridoma producing monoclonal antibody F4 which specifically binds to multidrug resistant P-glycoprotein and assays for detection of P-glycoprotein (United States Patent 5,503,984)

Hybridomas producing monoclonal antibodies specific for C-reactive protein and methods for detection of C-reactive protein (United States Patent 5,500,345)

Hybridoma and monoclonal antibody specific for human stem cell factor receptor and methods of use of the monoclonal antibody for detection of stem cell factor receptors (United States Patent 5,489,516)

Human anti-RH(D) monoclonal antibodies reagents and hybridomas and methods of RH typing using anti-RH(D) monoclonal antibodies and reagents (United States Patent 5,487,891)

Hybridomas and monoclonal antibodies that speifically bind to GPIB on platelets and inhibit the binding of thrombin to platelets (United States Patent 5,486,361)

Hybridomas and monoclonal antibodies which specifically bind human basic fibroblast growth factor (United States Patent 5,478,740)

Apolipoprotein B-specific monoclonal antibodies produced by two novel hybridomas (United States Patent 5,460,947)

Hybridomas producing monoclonal antibodies which specifically bind to continuous epitope on the human EGF receptor and compete with EGF for binding to the EGF receptor (United States Patent 5,459,061)

Hybridoma CT43 producing a monoclonal antibody to a novel mucin epitope which correlates with the presence of colorectal cancer (United States Patent 5,459,043)

Monoclonal antibodies specific for HIV and hybridomas for their production (United States Patent 5,445,960)

Monoclonal antibody against an acidic FGF protein and hybridoma for its production (United States Patent 5,437,995)

Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for assay of the inhibitors (United States Patent 5,422,245)

Chicken-specific immunoglobulin G-producing hybridoma (United States Patent 5,411,881)

Monoclonal antibodies to GP110 of HIV and hybridomas secreting these antibodies (United States Patent 5,407,811)

Class I MHC-restricted T-T hybridomas, and a CD8-transfected BW5147, fusion partner therefor (United States Patent 5,348,878)

Apolipoprotein B-specific monoclonal antibodies produced by two novel hybridomas (United States Patent 5,330,910)

Hybridoma producing a monoclonal antibody specific for an antigen of the stratum corneum of human epidermis (United States Patent 5,312,751)

Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide (United States Patent 5,300,434)

Human hybridomas and monoclonal antibodies which bind both gp41 and gp120 envelope proteins of human immunodeficiency virus (United States Patent 5,298,419)

Human-human hybridomas for neoplasms (United States Patent 5,286,647)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.