PATENTS RELATED TO LACTOBACILLUS

Although Dr. Demchick also represents patent seekers with non-microbiological inventions, his doctorate is in microbiology. Microbiology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving microbiology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of Lactobacillus related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Composition comprising a Lactobacillus pentosus strain and uses thereof (United States Patent 7,125,708)

Lactobacillus paracasei subsp. paracasei strain antibacterial against Helicobacter pylori and Escherichia coli 0157:h7 (United States Patent 7,090,840)

Lactobacillus rhamnosus polynucleotides, polypeptides and methods for using them (United States Patent 7,052,896)

Lactobacillus sp. strain and use thereof (United States Patent 7,026,161)

Microorganism strain of GM-020 of Lactobacillus rhamnosus and its use for treating obesity (United States Patent 7,001,756)

Lactobacillus paracasei strain GM-080 for treating allergy related diseases (United States Patent 6,994,848)

NADH oxidase from lactobacillus (United States Patent 6,987,013)

Levan-producing Lactobacillus strain and method of preparing human or pet food products using the same (United States Patent 6,932,991)

Expression contructs using Lactobacillus delbrueckii subsp. lactis lac repressor protein and its lac repressor binding site, microorganisms and methods thereof (United States Patent 6,929,931)

Lactobacillus helveticus producing antihypertensive di- and tripeptides (United States Patent 6,890,529)

Lactobacillus strains capable of preventing diarrhoea caused by pathogenic bacteria and rotaviruses (United States Patent 6,887,465)

Mutant Lactobacillus bulgaricus strains free from .beta.-galactoside activity (United States Patent 6,875,601)

Product containing Lactobacillus reuteri strain ATTC PTA-4965 or PTA-4964 for inhibiting bacteria causing dental caries (United States Patent 6,872,565)

Method for making mannitol with Lactobacillus intermedius (United States Patent 6,855,526)

Lactobacillus paracasei strain for preventing diarrhea caused by pathogenic bacteria (United States Patent 6,835,376)

Reduction of oxidative stress factors with Lactobacillus plantarum (United States Patent 6,830,750)

Lactobacillus KCTC 0774BP and acetobacter KCTC 0773BP for treatment or prevention of obesity and diabetes mellitus (United States Patent 6,808,703)

Probiotic composition containing Lactobacillus casei strain ATCC PTA-3945 (United States Patent 6,797,266)

Strain of Lactobacillus plantarum and uses thereof (United States Patent 6,761,885)

Pro-gut maturation and anti-inflammatory effects of lactobacillus and lactobacillus secreted proteins, carbohydrates and lipids (United States Patent 6,682,744)

Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide (United States Patent 6,664,097)

Lactic ferment comprising a particular strain of lactobacillus acidophilus and use thereof (United States Patent 6,607,905)

Strain of bacteria of the species Lactobacillus paracasei subsp. paracasei, composition thereof for use in food and product containing said strain (United States Patent 6,599,504)

Strain of Lactobacillus gasseri (United States Patent 6,596,530)

Lactobacillus helveticus bacterium having high capability of producing tripeptide, fermented milk product, and process for preparing the same (United States Patent 6,534,304)

Oral administration of lactobacillus for the treatment and prevention of urogenital infection (United States Patent 6,479,051)

Vaginal lactobacillus medicant (United States Patent 6,468,526)

Lactobacillus bifidus growth promoting composition and use thereof (United States Patent 6,451,584)

(R)-specific alcohol dehydrogenases from lactobacillus with improved catalytic activity using an NAD+ substrate (United States Patent 6,413,750)

Weight loss composition containing green tea, hydroxycitric acid, 5-hydroxytryptophan, glucomannan, picolinate and lactobacillus (United States Patent 6,383,482)

Vaginal lactobacillus medicant (United States Patent 6,372,209)

Synthetic medium for cultivating Lactobacillus and Bifidobacteria (United States Patent 6,340,585)

Nutrition supplement containing Lactobacillus acidophilus, yeast and soy protein (United States Patent 6,294,166)

Process for producing by culturing Lactobacillus casei var. rhamnosus yeast and mold inhibiting products (United States Patent 6,277,374)

Use of lactobacillus for reduction of the fibrinogen level in blood (United States Patent 6,214,336)

Lactobacillus compositions and methods for treating urinary tract infections (United States Patent 6,180,100)

Endopeptidase produced by Lactobacillus helveticus (United States Patent 6,168,939)

Strains of lactobacillus helveticus for forming exclusively L(+) lactic acid in milk (United States Patent 6,156,353)

Preventing/treating neonatal NEC by administering lactobacillus salivarius and lactobacillus plantarum or a combination thereof (United States Patent 6,132,710)

Lactobacillus reuteri to inhibit cryptosporidiosis in mammals (United States Patent 6,103,227)

Vaginal lactobacillus medicant (United States Patent 6,093,394)

Lactobacillus therapies (United States Patent 6,051,552)

Combinations of bacillus and lactobacillus species for producing protein from waste (United States Patent 6,025,187)

Bacterial strains of the genus Bacillus, closely phenotypically related to the genus Lactobacillus, culture method and use (United States Patent 6,022,537)

Lactobacillus and skim milk pharmaceutical compositions (United States Patent 6,004,551)

Process for producing yeast and mold inhibiting products with lactobacillus (United States Patent 5,965,414)

Strain of lactobacillus Plantarum (United States Patent 5,895,758)

Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals (United States Patent 5,858,356)

Lactobacillus sake like strains, production and use of their exopolysaccharides (United States Patent 5,834,043)

Lactobacillus compositions and methods for treating urinary tract infections (United States Patent 5,804,179)

Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate (United States Patent 5,798,237)

Gene integration into chromosomes of lactobacillus delbrueckii species and integrants thereof (United States Patent 5,747,310)

Lactobacillus strains of human origin, their compositons and uses thereof (United States Patent 5,709,857)

Lactic acid bacteria of the Genus lactobacillus (United States Patent 5,707,854)

Lactobacillus compositions and methods for treating urinary tract infections (United States Patent 5,705,160)

Plasmid pBUL1 derived from a lactobacillus and derivatives thereof (United States Patent 5,688,683)

Method using Lactobacillus AS-1 for inhibiting food spoilage (United States Patent 5,654,020)

Lactobacillus and skim milk compositions and methods for preventing microbial urogenital infections (United States Patent 5,645,830)

Plasmid derived from Lactobacillus elbrueckii Sp. (United States Patent 5,639,644)

Lactobacillus johnsonii CNCM I-1225 (United States Patent 5,603,930)

Lactobacillus used to enhance immunological functions (United States Patent 5,556,785)

Lactobacillus bulgaricus having decreased acid production and/or improved aroma and flavor production (United States Patent 5,545,554)

Lactobacillus helveticus mutants having low increase in acidity of lactic acid during storage (United States Patent 5,541,111)

Biologically pure culture of Lactobacillus acidophilus FERM-P-14204 or FERM-P-14205 (United States Patent 5,516,684)

Nucleic acid probes for the detection of bacteria of the genera Pediococcus and Lactobacillus and methods for the detection of the bacterial agents causing spoilage of beer (United States Patent 5,484,909)

Method for preparing an antitumor dextran using a dextran synthetase from Lactobacillus confusus (United States Patent 5,484,715)

Feed additive which consists of whey and Lactobacillus reuteri and a method of delivering Lactobacillus reuteri to the gastrointestinal tract (United States Patent 5,480,641)

In ovo method for delivering Lactobacillus reuteri to the gastrointestinal tract of poultry (United States Patent 5,458,875)

DNA probe for lactobacillus delbrueckii (United States Patent 5,429,924)

Plasmid pBUL1 derived from a lactobacillus and derivatives thereof (United States Patent 5,426,047)

Method for preparing an antitumor dextran using Lactobacillus confusus (United States Patent 5,424,201)

Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid (United States Patent 5,416,020)

Methodology employing lactobacillus GG for reduction of plasma endotoxin levels circulating in-vivo (United States Patent 5,413,785)

DNA probe for lactobacillus helveticus (United States Patent 5,412,086)

Lactobacillus casei ssp. rhamosus, bacterial preparations comprising said strain, and use of said strain and preparations for the controlling of yeast and moulds (United States Patent 5,378,458)

DNA probe for lactobacillus delbrueckii (United States Patent 5,359,049)

Lactobacillus casei (BP-4442) (United States Patent 5,354,687)

Method of determining the presence of an antibiotic produced by Lactobacillus reuteri (United States Patent 5,352,586)

Lactobacillus kefir alcohol dehydrogenase (United States Patent 5,342,767)

Procedure for the preparation of D-(-)-lactic acid with Lactobacillus bulgaricus (United States Patent 5,322,781)

Lactobacillus johnsonii ferm bp-2680 lactic acid bacteria preparations using the same and a process of manufacturing the preparations (United States Patent 5,296,221)

Method for the determination of .alpha.-ketoisocaproate in biological samples using D-.alpha.-hydroxyisocaproic dehydrogenase from lactobacillus casei (United States Patent 5,264,347)

Antibiotic resistant strain of lactobacillus acidophilus (United States Patent 5,256,425)

Lactobacillus kefir alcohol dehydrogenase (United States Patent 5,225,339)

Lactobacillus sp. KPB-167 and method of manufacturing viscose polysaccharides employing the same (United States Patent 5,204,247)

Antibiotic resistant strain of lactobacillus acidophilus (United States Patent 5,179,020)

Pharmaceutical compositions comprising selected lactobacillus strains (United States Patent 5,176,911)

Strains of lactobacillus for enhancing feed conversion efficiency (United States Patent 4,980,164)

Preparation of dried forms of leavening barms containing an admixture of certain lactobacillus and saccharomyces species (United States Patent 4,950,489)

Novel strain of Lactobacillus acidophilus (United States Patent 4,946,791)

Method and compositions for improving the nutritive value of foods via Lactobacillus Ferementum (United States Patent 4,889,810)

Method for inhibiting food-borne human pathogens and preventing microbial spoilage in refrigerated foods using a Lactobacillus (United States Patent 4,874,704)

Lactobacillus strains and methods of selection (United States Patent 4,839,281)

Shelf life and subsequent growth of lactobacillus acidophilus, propionibacterium shermanii and leuconostoc citrovorum in dietary fiber based supplement preparation (United States Patent 4,806,368)

Enhancement of lactobacillus acidophilus growth and viability in yogurt and other cultured dairy products (United States Patent 4,797,289)

Low temperature-sensitive variant of lactobacillus bulgaricus and a selection method therefor (United States Patent 4,734,361)

Admixture of a lactobacillus brevis and a saccharomyces dairensis for preparing leavening barm (United States Patent 4,666,719)

Composition for improved absorption of 2A cations and gold comprising yeast or Lactobacillus (United States Patent 4,591,503)

Fermentation method using a selected lactobacillus (United States Patent 4,579,740)

Novel lactobacillus and uses therefor (United States Patent 4,579,734)

Composition comprising a Lactobacillus pentosus strain and uses thereof (United States Patent 7,125,708)

Lactobacillus paracasei subsp. paracasei strain antibacterial against Helicobacter pylori and Escherichia coli 0157:h7 (United States Patent 7,090,840)

Lactobacillus rhamnosus polynucleotides, polypeptides and methods for using them (United States Patent 7,052,896)

Lactobacillus sp. strain and use thereof (United States Patent 7,026,161)

Microorganism strain of GM-020 of Lactobacillus rhamnosus and its use for treating obesity (United States Patent 7,001,756)

Lactobacillus paracasei strain GM-080 for treating allergy related diseases (United States Patent 6,994,848)

NADH oxidase from lactobacillus (United States Patent 6,987,013)

Levan-producing Lactobacillus strain and method of preparing human or pet food products using the same (United States Patent 6,932,991)

Expression contructs using Lactobacillus delbrueckii subsp. lactis lac repressor protein and its lac repressor binding site, microorganisms and methods thereof (United States Patent 6,929,931)

Lactobacillus helveticus producing antihypertensive di- and tripeptides (United States Patent 6,890,529)

Lactobacillus strains capable of preventing diarrhoea caused by pathogenic bacteria and rotaviruses (United States Patent 6,887,465)

Mutant Lactobacillus bulgaricus strains free from .beta.-galactoside activity (United States Patent 6,875,601)

Product containing Lactobacillus reuteri strain ATTC PTA-4965 or PTA-4964 for inhibiting bacteria causing dental caries (United States Patent 6,872,565)

Method for making mannitol with Lactobacillus intermedius (United States Patent 6,855,526)

Lactobacillus paracasei strain for preventing diarrhea caused by pathogenic bacteria (United States Patent 6,835,376)

Reduction of oxidative stress factors with Lactobacillus plantarum (United States Patent 6,830,750)

Lactobacillus KCTC 0774BP and acetobacter KCTC 0773BP for treatment or prevention of obesity and diabetes mellitus (United States Patent 6,808,703)

Probiotic composition containing Lactobacillus casei strain ATCC PTA-3945 (United States Patent 6,797,266)

Strain of Lactobacillus plantarum and uses thereof (United States Patent 6,761,885)

Pro-gut maturation and anti-inflammatory effects of lactobacillus and lactobacillus secreted proteins, carbohydrates and lipids (United States Patent 6,682,744)

Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide (United States Patent 6,664,097)

Lactic ferment comprising a particular strain of lactobacillus acidophilus and use thereof (United States Patent 6,607,905)

Strain of bacteria of the species Lactobacillus paracasei subsp. paracasei, composition thereof for use in food and product containing said strain (United States Patent 6,599,504)

Strain of Lactobacillus gasseri (United States Patent 6,596,530)

Lactobacillus helveticus bacterium having high capability of producing tripeptide, fermented milk product, and process for preparing the same (United States Patent 6,534,304)

Oral administration of lactobacillus for the treatment and prevention of urogenital infection (United States Patent 6,479,051)

Vaginal lactobacillus medicant (United States Patent 6,468,526)

Lactobacillus bifidus growth promoting composition and use thereof (United States Patent 6,451,584)

(R)-specific alcohol dehydrogenases from lactobacillus with improved catalytic activity using an NAD+ substrate (United States Patent 6,413,750)

Weight loss composition containing green tea, hydroxycitric acid, 5-hydroxytryptophan, glucomannan, picolinate and lactobacillus (United States Patent 6,383,482)

Vaginal lactobacillus medicant (United States Patent 6,372,209)

Synthetic medium for cultivating Lactobacillus and Bifidobacteria (United States Patent 6,340,585)

Nutrition supplement containing Lactobacillus acidophilus, yeast and soy protein (United States Patent 6,294,166)

Process for producing by culturing Lactobacillus casei var. rhamnosus yeast and mold inhibiting products (United States Patent 6,277,374)

Use of lactobacillus for reduction of the fibrinogen level in blood (United States Patent 6,214,336)

Lactobacillus compositions and methods for treating urinary tract infections (United States Patent 6,180,100)

Endopeptidase produced by Lactobacillus helveticus (United States Patent 6,168,939)

Strains of lactobacillus helveticus for forming exclusively L(+) lactic acid in milk (United States Patent 6,156,353)

Preventing/treating neonatal NEC by administering lactobacillus salivarius and lactobacillus plantarum or a combination thereof (United States Patent 6,132,710)

Lactobacillus reuteri to inhibit cryptosporidiosis in mammals (United States Patent 6,103,227)

Vaginal lactobacillus medicant (United States Patent 6,093,394)

Lactobacillus therapies (United States Patent 6,051,552)

Combinations of bacillus and lactobacillus species for producing protein from waste (United States Patent 6,025,187)

Bacterial strains of the genus Bacillus, closely phenotypically related to the genus Lactobacillus, culture method and use (United States Patent 6,022,537)

Lactobacillus and skim milk pharmaceutical compositions (United States Patent 6,004,551)

Process for producing yeast and mold inhibiting products with lactobacillus (United States Patent 5,965,414)

Strain of lactobacillus Plantarum (United States Patent 5,895,758)

Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals (United States Patent 5,858,356)

Lactobacillus sake like strains, production and use of their exopolysaccharides (United States Patent 5,834,043)

Lactobacillus compositions and methods for treating urinary tract infections (United States Patent 5,804,179)

Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate (United States Patent 5,798,237)

Gene integration into chromosomes of lactobacillus delbrueckii species and integrants thereof (United States Patent 5,747,310)

Lactobacillus strains of human origin, their compositons and uses thereof (United States Patent 5,709,857)

Lactic acid bacteria of the Genus lactobacillus (United States Patent 5,707,854)

Lactobacillus compositions and methods for treating urinary tract infections (United States Patent 5,705,160)

Plasmid pBUL1 derived from a lactobacillus and derivatives thereof (United States Patent 5,688,683)

Method using Lactobacillus AS-1 for inhibiting food spoilage (United States Patent 5,654,020)

Lactobacillus and skim milk compositions and methods for preventing microbial urogenital infections (United States Patent 5,645,830)

Plasmid derived from Lactobacillus elbrueckii Sp. (United States Patent 5,639,644)

Lactobacillus johnsonii CNCM I-1225 (United States Patent 5,603,930)

Lactobacillus used to enhance immunological functions (United States Patent 5,556,785)

Lactobacillus bulgaricus having decreased acid production and/or improved aroma and flavor production (United States Patent 5,545,554)

Lactobacillus helveticus mutants having low increase in acidity of lactic acid during storage (United States Patent 5,541,111)

Biologically pure culture of Lactobacillus acidophilus FERM-P-14204 or FERM-P-14205 (United States Patent 5,516,684)

Nucleic acid probes for the detection of bacteria of the genera Pediococcus and Lactobacillus and methods for the detection of the bacterial agents causing spoilage of beer (United States Patent 5,484,909)

Method for preparing an antitumor dextran using a dextran synthetase from Lactobacillus confusus (United States Patent 5,484,715)

Feed additive which consists of whey and Lactobacillus reuteri and a method of delivering Lactobacillus reuteri to the gastrointestinal tract (United States Patent 5,480,641)

In ovo method for delivering Lactobacillus reuteri to the gastrointestinal tract of poultry (United States Patent 5,458,875)

DNA probe for lactobacillus delbrueckii (United States Patent 5,429,924)

Plasmid pBUL1 derived from a lactobacillus and derivatives thereof (United States Patent 5,426,047)

Method for preparing an antitumor dextran using Lactobacillus confusus (United States Patent 5,424,201)

Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid (United States Patent 5,416,020)

Methodology employing lactobacillus GG for reduction of plasma endotoxin levels circulating in-vivo (United States Patent 5,413,785)

DNA probe for lactobacillus helveticus (United States Patent 5,412,086)

Lactobacillus casei ssp. rhamosus, bacterial preparations comprising said strain, and use of said strain and preparations for the controlling of yeast and moulds (United States Patent 5,378,458)

DNA probe for lactobacillus delbrueckii (United States Patent 5,359,049)

Lactobacillus casei (BP-4442) (United States Patent 5,354,687)

Method of determining the presence of an antibiotic produced by Lactobacillus reuteri (United States Patent 5,352,586)

Lactobacillus kefir alcohol dehydrogenase (United States Patent 5,342,767)

Procedure for the preparation of D-(-)-lactic acid with Lactobacillus bulgaricus (United States Patent 5,322,781)

Lactobacillus johnsonii ferm bp-2680 lactic acid bacteria preparations using the same and a process of manufacturing the preparations (United States Patent 5,296,221)

Method for the determination of .alpha.-ketoisocaproate in biological samples using D-.alpha.-hydroxyisocaproic dehydrogenase from lactobacillus casei (United States Patent 5,264,347)

Antibiotic resistant strain of lactobacillus acidophilus (United States Patent 5,256,425)

Lactobacillus kefir alcohol dehydrogenase (United States Patent 5,225,339)

Lactobacillus sp. KPB-167 and method of manufacturing viscose polysaccharides employing the same (United States Patent 5,204,247)

Antibiotic resistant strain of lactobacillus acidophilus (United States Patent 5,179,020)

Pharmaceutical compositions comprising selected lactobacillus strains (United States Patent 5,176,911)

Strains of lactobacillus for enhancing feed conversion efficiency (United States Patent 4,980,164)

Preparation of dried forms of leavening barms containing an admixture of certain lactobacillus and saccharomyces species (United States Patent 4,950,489)

Novel strain of Lactobacillus acidophilus (United States Patent 4,946,791)

Method and compositions for improving the nutritive value of foods via Lactobacillus Ferementum (United States Patent 4,889,810)

Method for inhibiting food-borne human pathogens and preventing microbial spoilage in refrigerated foods using a Lactobacillus (United States Patent 4,874,704)

Lactobacillus strains and methods of selection (United States Patent 4,839,281)

Shelf life and subsequent growth of lactobacillus acidophilus, propionibacterium shermanii and leuconostoc citrovorum in dietary fiber based supplement preparation (United States Patent 4,806,368)

Enhancement of lactobacillus acidophilus growth and viability in yogurt and other cultured dairy products (United States Patent 4,797,289)

Low temperature-sensitive variant of lactobacillus bulgaricus and a selection method therefor (United States Patent 4,734,361)

Admixture of a lactobacillus brevis and a saccharomyces dairensis for preparing leavening barm (United States Patent 4,666,719)

Composition for improved absorption of 2A cations and gold comprising yeast or Lactobacillus (United States Patent 4,591,503)

Fermentation method using a selected lactobacillus (United States Patent 4,579,740)

Novel lactobacillus and uses therefor (United States Patent 4,579,734)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.