PATENTS RELATED TO MICROBIOLOGY

Although Dr. Demchick also represents patent seekers with non-microbiological inventions, his doctorate is in microbiology. Microbiology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving microbiology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of microbiology related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Bovine immunodeficiency virus (BIV) based vectors (United States Patent 7,153,512)

Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,151,105)

Lactic acid bacteria-containing probiotics products (United States Patent 7,150,986)

AAV DNA comprising helper virus sequences (United States Patent 7,148,341)

Compositions and methods for regulating autolytic processes in bacteria (United States Patent 7,148,328)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,148,226)

Complex of Hepatitis B virus polymerase with p11 and method for controlling movement of the complex in HepG2 cell (United States Patent 7,148,013)

Screening methods to identify agents that selectively inhibit hepatitis C virus replication (United States Patent 7,148,006)

Nucleic acid-based methods of detecting bacterial o-antigens (United States Patent 7,148,005)

Use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction and pharmaceutical or dietetic compositions containing such bacteria (United States Patent 7,147,847)

Crystalline forms of carbapenem antibiotics and methods of preparation (United States Patent 7,145,002)

Antibacterial compounds and methods for treating Gram positive bacterial infections (United States Patent 7,144,858)

Protein complex from ion-exchange chromatography for treatment of bacterial infections (United States Patent 7,144,855)

Process for the production of L-amino acids by fermentation using coryneform bacteria (United States Patent 7,144,724)

Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof (United States Patent 7,144,712)

Postweaning multisystemic wasting syndrome virus from pigs (United States Patent 7,144,698)

Synthetic antigen for the detection of antibodies immunoreactive with HIV virus (United States Patent 7,144,697)

Oxazolidinone derivatives with antibiotic activity (United States Patent 7,141,583)

Chimeric GB virus B (GBV-B) (United States Patent 7,141,405)

Hepatitis B virus surface antigen mutant and methods of detection thereof (United States Patent 7,141,242)

Use of bacterial phage associated lysing enzymes for treating upper respiratory illnesses (United States Patent 7,141,241)

Bacterial retentive, air venting, intravenous filter (United States Patent 7,141,097)

Reducing the level of bacteria and viruses in aquaculture (United States Patent 7,140,323)

Extractive purification of lipopeptide antibiotics (United States Patent 7,138,487)

Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides (United States Patent 7,138,376)

Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 7,138,266)

Infectious bovine viral diarrhea virus clone (United States Patent 7,135,561)

Hepatitis C virus inhibitors (United States Patent 7,135,462)

Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) (United States Patent 7,135,339)

Varicella zoster virus (VZV) immunoreactive protein VP26 and its diagnostic use (United States Patent 7,135,186)

Conserved motif of hepatitis C virus E2/NS1 region (United States Patent 7,135,185)

Compositions and methods for eliciting an immune response to gram-negative bacterial infections (United States Patent 7,135,175)

Means for identifying a novel class of genes resistant to the rice yellow mottle virus and the locus of a major gene of resistance to the virus, and their applications (United States Patent 7,132,514)

Hepatitis C virus inhibitors (United States Patent 7,132,504)

Method of using prostacyclin to treat respiratory syncytial virus infections (United States Patent 7,132,453)

Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection (United States Patent 7,132,452)

Process for producing isoprenoid compounds by microorganisms and a method for screening compounds with antibiotic or weeding activity (United States Patent 7,132,268)

Papilloma virus sequences (United States Patent 7,132,262)

Production or aromatic carotenoids in gram negative bacteria (United States Patent 7,132,257)

Method and apparatus for detecting phycocyanin-pigmented algae and bacteria from reflected light (United States Patent 7,132,254)

Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus (United States Patent 7,132,233)

Biodegradable and biocompatible polymeric microspheres encapsulating Salmonella enteritidis bacteria (United States Patent 7,132,108)

Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof (United States Patent 7,132,106)

Icosahedral superstructure of VP2 of infectious bursitis virus (IBDV) and the application thereof (United States Patent 7,132,105)

Bacteriocins and novel bacterial strains (United States Patent 7,132,102)

Compositions and methods for eliciting an immune response to gram-negative bacterial infections (United States Patent 7,132,101)

Infectious cDNA clone of GB virus B and uses thereof (United States Patent 7,129,342)

Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents (United States Patent 7,129,337)

Antibiotic Cyan426-A (United States Patent 7,129,266)

Nucleic acid and amino acid sequences of infectious salmon anaemia virus and their use as vaccines (United States Patent 7,128,917)

Membrane virus host range mutations and their uses as vaccine substrates (United States Patent 7,128,915)

Plant genes conferring resistance to Citrus tristeza virus (United States Patent 7,126,044)

Nucleic acid fragments for the identification of bacteria in industrial wastewater bioreactors (United States Patent 7,125,981)

Nucleic acid fragments for the identification of bacteria in industrial wastewater bioreactors (United States Patent 7,125,980)

Genes for heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic coryneform bacteria (United States Patent 7,125,977)

Full-length genomic RNA of papaya leaf-distortion mosaic virus (United States Patent 7,125,971)

Dab.sup.9 derivatives of lipopeptide antibiotics and methods of making and using the same (United States Patent 7,125,844)

Method for introducing and expressing genes in animal cells, and bacterial blebs for use in same (United States Patent 7,125,718)

Bovine immunodeficiency virus (BIV) based vectors (United States Patent 7,125,712)

Polynucleotides for use in recombinant adeno-associated virus virion production (United States Patent 7,125,705)

Promoters showing stationary phase-specific activity in gram-positive bacteria (United States Patent 7,125,690)

Method of identifying putative antibiotic resistance genes (United States Patent 7,125,662)

Lactam inhibitors of Hepatitis C virus NS3 protease (United States Patent 7,122,627)

Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains (United States Patent 7,122,514)

Formulations to increase in vivo survival of probiotic bacteria and extend their shelf-life (United States Patent 7,122,370)

Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production (United States Patent 7,122,369)

Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents (United States Patent 7,122,306)

Antibiotic composition with inhibitor (United States Patent 7,122,204)

Antibodies which bind with proteins of human immunodeficiency virus type 1 (HIV-1), and immune complexes comprising proteins of HIV-1 (United States Patent 7,122,188)

Oncolytic virus therapy (United States Patent 7,122,182)

DNA sequences and peptides of human immunodeficiency virus (HIV-1) (United States Patent 7,119,181)

2-halogenated derivatives of 5-O-desosaminyl-erythronolide A, their preparation process and their antibiotic use (United States Patent 7,119,180)

Inhibitors of papilloma virus (United States Patent 7,119,099)

Peptides and their use as inhibitors of hepatitis C virus ns3 protease (United States Patent 7,119,073)

Macrocyclic peptides active against the hepatitis C virus (United States Patent 7,119,072)

Dalbavancin compositions for treatment of bacterial infections (United States Patent 7,119,061)

DNA molecules stabilized for propagation in bacterial cells that encode cystic fibrosis transmembrane conductance regulator (United States Patent 7,118,911)

Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production (United States Patent 7,118,894)

Detection of fecal contamination using nucleic acid molecules that recognize bacterial 16S rDNA sequences (United States Patent 7,118,870)

Transformed bacteria producing CS6 antigens as vaccines (United States Patent 7,118,758)

Ligand for herpes simplex virus entry mediator and methods of use (United States Patent 7,118,742)

Method for limiting the growth of cancer cells using an attenuated measles virus (United States Patent 7,118,740)

Recombinant pox virus for immunization against MUC1 tumor-associated antigen (United States Patent 7,118,738)

Process for removing protein aggregates and virus from a protein solution (United States Patent 7,118,675)

Triaryl cation antibiotics from environmental DNA (United States Patent 7,115,753)

Nucleic acid, nucleic acid for detecting dechlorination bacteria, probe, method for detecting dechlorination bacteria and method for treating earth or underground water polluted by chlorinated ethylene or chlorinated ethane (United States Patent 7,115,734)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase (United States Patent 7,115,658)

Water-soluble antibiotic comprising an amino sugar, in the form of a polysaccharide conjugate (United States Patent 7,115,576)

Bacterial strain for degradation of organic polymers (United States Patent 7,115,411)

Compositions and methods for detecting West Nile virus (United States Patent 7,115,374)

Cycloalkyl heterocycles for treating hepatitis C virus (United States Patent 7,112,601)

Dual expression vector system for antibody expression in bacterial and mammalian cells (United States Patent 7,112,439)

Vaccines against varicella zoster virus gene 63 product (United States Patent 7,112,331)

Intracellular proteinacious antimicrobial agents from lactic acid bacteria derived from fermented food samples (United States Patent 7,112,323)

Adeno-associated virus-mediated delivery of GDNF to skeletal muscles (United States Patent 7,112,321)

Bacterial glycosyltransferase polypeptides involved in antibiotic resistance (United States Patent 7,109,294)

Carbacephem .beta.-lactam antibiotics (United States Patent 7,109,190)

Bovine immunodeficiency virus (BIV) based vectors (United States Patent 7,153,512)

Network anti-virus system (United States Patent 7,152,164)

Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,151,105)

Lactic acid bacteria-containing probiotics products (United States Patent 7,150,986)

AAV DNA comprising helper virus sequences (United States Patent 7,148,341)

Compositions and methods for regulating autolytic processes in bacteria (United States Patent 7,148,328)

Major neutralization site of hepatitis E virus and use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to hepatitis E virus (United States Patent 7,148,323)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same (United States Patent 7,148,226)

Complex of Hepatitis B virus polymerase with p11 and method for controlling movement of the complex in HepG2 cell (United States Patent 7,148,013)

Screening methods to identify agents that selectively inhibit hepatitis C virus replication (United States Patent 7,148,006)

Nucleic acid-based methods of detecting bacterial o-antigens (United States Patent 7,148,005)

Use of bacteria endowed with arginine deiminase to induce apoptosis and/or reduce an inflammatory reaction and pharmaceutical or dietetic compositions containing such bacteria (United States Patent 7,147,847)

Crystalline forms of carbapenem antibiotics and methods of preparation (United States Patent 7,145,002)

Antibacterial compounds and methods for treating Gram positive bacterial infections (United States Patent 7,144,858)

Protein complex from ion-exchange chromatography for treatment of bacterial infections (United States Patent 7,144,855)

Process for the production of L-amino acids by fermentation using coryneform bacteria (United States Patent 7,144,724)

Human hepatitis B virus core proteins as vaccine platforms and methods of use thereof (United States Patent 7,144,712)

Postweaning multisystemic wasting syndrome virus from pigs (United States Patent 7,144,698)

Synthetic antigen for the detection of antibodies immunoreactive with HIV virus (United States Patent 7,144,697)

Oxazolidinone derivatives with antibiotic activity (United States Patent 7,141,583)

Chimeric GB virus B (GBV-B) (United States Patent 7,141,405)

Hepatitis B virus surface antigen mutant and methods of detection thereof (United States Patent 7,141,242)

Use of bacterial phage associated lysing enzymes for treating upper respiratory illnesses (United States Patent 7,141,241)

Bacterial retentive, air venting, intravenous filter (United States Patent 7,141,097)

Reducing the level of bacteria and viruses in aquaculture (United States Patent 7,140,323)

Extractive purification of lipopeptide antibiotics (United States Patent 7,138,487)

Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides (United States Patent 7,138,376)

Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine (United States Patent 7,138,266)

Infectious bovine viral diarrhea virus clone (United States Patent 7,135,561)

Hepatitis C virus inhibitors (United States Patent 7,135,462)

Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) (United States Patent 7,135,339)

Varicella zoster virus (VZV) immunoreactive protein VP26 and its diagnostic use (United States Patent 7,135,186)

Conserved motif of hepatitis C virus E2/NS1 region (United States Patent 7,135,185)

Compositions and methods for eliciting an immune response to gram-negative bacterial infections (United States Patent 7,135,175)

Means for identifying a novel class of genes resistant to the rice yellow mottle virus and the locus of a major gene of resistance to the virus, and their applications (United States Patent 7,132,514)

Hepatitis C virus inhibitors (United States Patent 7,132,504)

Method of using prostacyclin to treat respiratory syncytial virus infections (United States Patent 7,132,453)

Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection (United States Patent 7,132,452)

Process for producing isoprenoid compounds by microorganisms and a method for screening compounds with antibiotic or weeding activity (United States Patent 7,132,268)

Papilloma virus sequences (United States Patent 7,132,262)

Production or aromatic carotenoids in gram negative bacteria (United States Patent 7,132,257)

Method and apparatus for detecting phycocyanin-pigmented algae and bacteria from reflected light (United States Patent 7,132,254)

Identification of oligonucleotides for the capture, detection and quantitation of West Nile virus (United States Patent 7,132,233)

Biodegradable and biocompatible polymeric microspheres encapsulating Salmonella enteritidis bacteria (United States Patent 7,132,108)

Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof (United States Patent 7,132,106)

Icosahedral superstructure of VP2 of infectious bursitis virus (IBDV) and the application thereof (United States Patent 7,132,105)

Bacteriocins and novel bacterial strains (United States Patent 7,132,102)

Compositions and methods for eliciting an immune response to gram-negative bacterial infections (United States Patent 7,132,101)

Infectious cDNA clone of GB virus B and uses thereof (United States Patent 7,129,342)

Sequences of hepatitis C virus genotypes and their use as prophylactic, therapeutic and diagnostic agents (United States Patent 7,129,337)

Antibiotic Cyan426-A (United States Patent 7,129,266)

Nucleic acid and amino acid sequences of infectious salmon anaemia virus and their use as vaccines (United States Patent 7,128,917)

Membrane virus host range mutations and their uses as vaccine substrates (United States Patent 7,128,915)

Plant genes conferring resistance to Citrus tristeza virus (United States Patent 7,126,044)

Nucleic acid fragments for the identification of bacteria in industrial wastewater bioreactors (United States Patent 7,125,981)

Nucleic acid fragments for the identification of bacteria in industrial wastewater bioreactors (United States Patent 7,125,980)

Genes for heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic coryneform bacteria (United States Patent 7,125,977)

Full-length genomic RNA of papaya leaf-distortion mosaic virus (United States Patent 7,125,971)

Dab.sup.9 derivatives of lipopeptide antibiotics and methods of making and using the same (United States Patent 7,125,844)

Method for introducing and expressing genes in animal cells, and bacterial blebs for use in same (United States Patent 7,125,718)

Bovine immunodeficiency virus (BIV) based vectors (United States Patent 7,125,712)

Polynucleotides for use in recombinant adeno-associated virus virion production (United States Patent 7,125,705)

Promoters showing stationary phase-specific activity in gram-positive bacteria (United States Patent 7,125,690)

Method of identifying putative antibiotic resistance genes (United States Patent 7,125,662)

Lactam inhibitors of Hepatitis C virus NS3 protease (United States Patent 7,122,627)

Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains (United States Patent 7,122,514)

Formulations to increase in vivo survival of probiotic bacteria and extend their shelf-life (United States Patent 7,122,370)

Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production (United States Patent 7,122,369)

Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents (United States Patent 7,122,306)

Antibiotic composition with inhibitor (United States Patent 7,122,204)

Antibodies which bind with proteins of human immunodeficiency virus type 1 (HIV-1), and immune complexes comprising proteins of HIV-1 (United States Patent 7,122,188)

Oncolytic virus therapy (United States Patent 7,122,182)

DNA sequences and peptides of human immunodeficiency virus (HIV-1) (United States Patent 7,119,181)

2-halogenated derivatives of 5-O-desosaminyl-erythronolide A, their preparation process and their antibiotic use (United States Patent 7,119,180)

Inhibitors of papilloma virus (United States Patent 7,119,099)

Peptides and their use as inhibitors of hepatitis C virus ns3 protease (United States Patent 7,119,073)

Macrocyclic peptides active against the hepatitis C virus (United States Patent 7,119,072)

Dalbavancin compositions for treatment of bacterial infections (United States Patent 7,119,061)

DNA molecules stabilized for propagation in bacterial cells that encode cystic fibrosis transmembrane conductance regulator (United States Patent 7,118,911)

Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production (United States Patent 7,118,894)

Detection of fecal contamination using nucleic acid molecules that recognize bacterial 16S rDNA sequences (United States Patent 7,118,870)

Transformed bacteria producing CS6 antigens as vaccines (United States Patent 7,118,758)

Ligand for herpes simplex virus entry mediator and methods of use (United States Patent 7,118,742)

Method for limiting the growth of cancer cells using an attenuated measles virus (United States Patent 7,118,740)

Recombinant pox virus for immunization against MUC1 tumor-associated antigen (United States Patent 7,118,738)

Process for removing protein aggregates and virus from a protein solution (United States Patent 7,118,675)

Triaryl cation antibiotics from environmental DNA (United States Patent 7,115,753)

Nucleic acid, nucleic acid for detecting dechlorination bacteria, probe, method for detecting dechlorination bacteria and method for treating earth or underground water polluted by chlorinated ethylene or chlorinated ethane (United States Patent 7,115,734)

Inhibitors of hepatitis C virus RNA-dependent RNA polymerase (United States Patent 7,115,658)

Water-soluble antibiotic comprising an amino sugar, in the form of a polysaccharide conjugate (United States Patent 7,115,576)

Bacterial strain for degradation of organic polymers (United States Patent 7,115,411)

Compositions and methods for detecting West Nile virus (United States Patent 7,115,374)

Cycloalkyl heterocycles for treating hepatitis C virus (United States Patent 7,112,601)

Dual expression vector system for antibody expression in bacterial and mammalian cells (United States Patent 7,112,439)

Vaccines against varicella zoster virus gene 63 product (United States Patent 7,112,331)

Intracellular proteinacious antimicrobial agents from lactic acid bacteria derived from fermented food samples (United States Patent 7,112,323)

Adeno-associated virus-mediated delivery of GDNF to skeletal muscles (United States Patent 7,112,321)

Bacterial glycosyltransferase polypeptides involved in antibiotic resistance (United States Patent 7,109,294)

Carbacephem .beta.-lactam antibiotics (United States Patent 7,109,190)

Bovine immunodeficiency virus (BIV) based vectors (United States Patent 7,153,512)

Network anti-virus system (United States Patent 7,152,164)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.