PATENTS RELATED TO MITOCHONDRIA

Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of mitochondria related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Mitochondrial creatine kinase antibody (United States Patent 7,148,063)

Culturable mitochondrial cells with no nucleus, showing mitochondrial activity (United States Patent 7,125,716)

Non-invasive diagnostic imaging technology for mitochondria dysfunction using radiolabeled lipophilic salts (United States Patent 7,112,318)

Mitochondrially targeted antioxidants (United States Patent 7,109,189)

Method for determining chum salmon haplotype using mitochondrial DNA (United States Patent 7,105,299)

Mimetics and inhibitors of the interaction between Vpr (HIV viral protein of regulation) and ANT (Mitochondrial adenine nucleotide translocator) (United States Patent 7,056,735)

Human mitochondrial proteins and polynucleotides encoding the proteins (United States Patent 7,026,452)

Mitochondrially targeted antioxidants (United States Patent 6,984,636)

Compositions and methods for treatment of mitochondrial diseases (United States Patent 6,956,028)

(1-phenyl-2-heteoaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase (United States Patent 6,916,813)

Method of targeting conjugate molecules to mitochondria (United States Patent 6,867,197)

Use of fumaric acid derivatives for treating mitochondrial diseases (United States Patent 6,858,750)

Simple and quick method for determining the nucleotide sequence of a mitochondrial 21S ribosomal RNA gene of yeast belonging to Saccharomyces cerevisiae (United States Patent 6,852,489)

N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase (United States Patent 6,846,836)

Compositions and methods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions (United States Patent 6,797,467)

Human mitochondrial proteins and polynucleotides encoding the same (United States Patent 6,790,667)

Method of detecting mitochondrial dysfunction (United States Patent 6,759,196)

Subtle mitochondrial mutations as tumor markers (United States Patent 6,750,021)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,653,094)

Mitochondrial dosimeter (United States Patent 6,605,433)

Methods to identify compounds affecting mitochondria (United States Patent 6,586,241)

Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions (United States Patent 6,562,563)

Compounds for altering mitochondrial function and cellular responses (United States Patent 6,552,076)

Mitochondria protecting agents for treating mitochondria associated diseases (United States Patent 6,511,966)

Mitochondria protecting agents for treating mitochondria associated diseases (United States Patent 6,498,191)

Transgenic plants including a transgene consisting of a hybrid nucleic acid sequence, comprising at least one unedited mitochondrial gene fragment from higher plants and process for producing them (United States Patent 6,479,735)

Methods and compositions for the protection of mitochondria (United States Patent 6,479,533)

Colorimetric test for agents that induce mitochondrial dysfunction (United States Patent 6,479,251)

Compositions and methods for treatment of mitochondrial diseases (United States Patent 6,472,378)

Nutritional assessment by measuring mitochondrial complex activity (United States Patent 6,455,243)

Human mitochondrial chaperone protein (United States Patent 6,432,915)

Mitochondrial membrane stabilizer (United States Patent 6,417,220)

Subtle mitochondrial mutations as tumor markers (United States Patent 6,344,322)

Mitochondrially targeted antioxidants (United States Patent 6,331,532)

Mitochondrial DNA damage as a predictor of coronary atherosclerotic heart disease (United States Patent 6,322,974)

Use of a compound with affinity for the mitochondrial benzodiazepine receptor in cancer therapy (United States Patent 6,319,931)

Drug mitochondrial targeting agents (United States Patent 6,316,652)

Cyanine dyes that stain cells and mitochondria (United States Patent 6,291,203)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,280,966)

Human mitochondrial malate dehydrogenase (United States Patent 6,274,138)

Compounds and methods for treating mitochondria-associated diseases (United States Patent 6,268,398)

Method and kit for measuring mitochondrial activity (United States Patent 6,261,796)

Composition for improvement of cellular nutrition and mitochondrial energetics (United States Patent 6,232,346)

Method for diagnosing preclinical diabetes by quantification of mitochondrial DNA in peripheral blood (United States Patent 6,232,078)

Bacterial expression systems based on plastic or mitochondrial promoter combinations (United States Patent 6,218,145)

Methods to identify compounds affecting mitochondria (United States Patent 6,183,948)

Method of targeting conjugate molecules to mitochondria (United States Patent 6,171,859)

Cellular models for diabetes and other diseases associated with mitochondrial defects (United States Patent 6,146,831)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,140,067)

Methods and compositions for the protection of mitochondria (United States Patent 6,103,746)

Method of protein production using mitochondrial translation system (United States Patent 6,100,068)

Composition for improvement of cellular nutrition and mitochondrial energetics (United States Patent 6,080,788)

Antisense inhibition of PEPCK-mitochondrial expression (United States Patent 6,030,837)

Optimal procedure for isolation of mutant mitochondrial alleles (United States Patent 6,027,883)

Polynucleotides encoding human mitochondrial chaperone proteins (United States Patent 6,010,879)

Mitochondrial processing peptidase subunit (United States Patent 6,001,629)

Mitochondrial adenylate kinase (United States Patent 6,001,624)

Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid (United States Patent 5,976,798)

Transgenic plants including a transgene consisting of a hybrid nucleic acid sequence, comprising at least one unedited mitochondrial gene fragment from higher plants and process for producing them (United States Patent 5,914,447)

Mutant gene causing a defect in mitochondrial recombination and a method for its detection (United States Patent 5,908,747)

Cellular and animal models for diseases associated with mitochondrial defects (United States Patent 5,888,498)

Mitochondrial processing peptidase subunit (United States Patent 5,869,311)

Mitochondrial adenylate kinase (United States Patent 5,856,160)

Human mitochondrial membrane protein (United States Patent 5,854,414)

Diagnostic agent for hypoxia or mitochondrial dysfunction comprising radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative (United States Patent 5,843,400)

Mitochondrial DNA mutations that segregate with late onset diabetes mellitus (United States Patent 5,840,493)

Species-specific mitochondrial sequences for identification of Tilletia indica, the karnal bunt wheat fungus and methods of using said sequences (United States Patent 5,811,240)

DNA sequence imparting cytoplasmic male sterility, mitochondrial genome, nuclear genome, mitochondria and plant containing said sequence and process for the preparation of hybrids (United States Patent 5,789,566)

Isolated nucleotide sequences corresponding to mitochondrial cytochrome oxidase genes (United States Patent 5,760,205)

Application of riluzole in the treatment of mitochondrial diseases (United States Patent 5,686,475)

Xanthylium dyes that are well retained in mitochondria (United States Patent 5,686,261)

Detection of mitochondrial DNA mutation 14459 associated with dystonia and/or Leber's hereditary optic neuropathy (United States Patent 5,670,320)

Mitochondrial P450 (United States Patent 5,668,000)

Maize cytoplasmic male sterility type T (cms-T) mitochondria DNA (United States Patent 5,660,983)

RNA import elements for transport into mitochondria (United States Patent 5,569,754)

Detection of mitochondrial DNA mutations associated with Alzheimer's disease and Parkinson's disease (United States Patent 5,494,794)

Xanthylium dyes that are well retained in mitochondria (United States Patent 5,459,268)

Association of bovine mitochondrial DNA with traits of economic importance (United States Patent 5,292,639)

Hybrid vector and process for improving the amplification and expression of hybrid vectors by the use of mitochondrial DNA (United States Patent 4,492,758)

Method for determination of cytoplasmatic and mitochondrial isoenzymes of glutamic-oxalacetic transaminase in human serum or plasma (United States Patent 4,477,566)

Mitochondrial creatine kinase antibody (United States Patent 7,148,063)

Culturable mitochondrial cells with no nucleus, showing mitochondrial activity (United States Patent 7,125,716)

Non-invasive diagnostic imaging technology for mitochondria dysfunction using radiolabeled lipophilic salts (United States Patent 7,112,318)

Mitochondrially targeted antioxidants (United States Patent 7,109,189)

Method for determining chum salmon haplotype using mitochondrial DNA (United States Patent 7,105,299)

Mimetics and inhibitors of the interaction between Vpr (HIV viral protein of regulation) and ANT (Mitochondrial adenine nucleotide translocator) (United States Patent 7,056,735)

Human mitochondrial proteins and polynucleotides encoding the proteins (United States Patent 7,026,452)

Mitochondrially targeted antioxidants (United States Patent 6,984,636)

Compositions and methods for treatment of mitochondrial diseases (United States Patent 6,956,028)

(1-phenyl-2-heteoaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase (United States Patent 6,916,813)

Method of targeting conjugate molecules to mitochondria (United States Patent 6,867,197)

Use of fumaric acid derivatives for treating mitochondrial diseases (United States Patent 6,858,750)

Simple and quick method for determining the nucleotide sequence of a mitochondrial 21S ribosomal RNA gene of yeast belonging to Saccharomyces cerevisiae (United States Patent 6,852,489)

N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase (United States Patent 6,846,836)

Compositions and methods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions (United States Patent 6,797,467)

Human mitochondrial proteins and polynucleotides encoding the same (United States Patent 6,790,667)

Method of detecting mitochondrial dysfunction (United States Patent 6,759,196)

Subtle mitochondrial mutations as tumor markers (United States Patent 6,750,021)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,653,094)

Mitochondrial dosimeter (United States Patent 6,605,433)

Methods to identify compounds affecting mitochondria (United States Patent 6,586,241)

Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions (United States Patent 6,562,563)

Compounds for altering mitochondrial function and cellular responses (United States Patent 6,552,076)

Mitochondria protecting agents for treating mitochondria associated diseases (United States Patent 6,511,966)

Mitochondria protecting agents for treating mitochondria associated diseases (United States Patent 6,498,191)

Transgenic plants including a transgene consisting of a hybrid nucleic acid sequence, comprising at least one unedited mitochondrial gene fragment from higher plants and process for producing them (United States Patent 6,479,735)

Methods and compositions for the protection of mitochondria (United States Patent 6,479,533)

Colorimetric test for agents that induce mitochondrial dysfunction (United States Patent 6,479,251)

Compositions and methods for treatment of mitochondrial diseases (United States Patent 6,472,378)

Nutritional assessment by measuring mitochondrial complex activity (United States Patent 6,455,243)

Human mitochondrial chaperone protein (United States Patent 6,432,915)

Mitochondrial membrane stabilizer (United States Patent 6,417,220)

Subtle mitochondrial mutations as tumor markers (United States Patent 6,344,322)

Mitochondrially targeted antioxidants (United States Patent 6,331,532)

Mitochondrial DNA damage as a predictor of coronary atherosclerotic heart disease (United States Patent 6,322,974)

Use of a compound with affinity for the mitochondrial benzodiazepine receptor in cancer therapy (United States Patent 6,319,931)

Drug mitochondrial targeting agents (United States Patent 6,316,652)

Cyanine dyes that stain cells and mitochondria (United States Patent 6,291,203)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,280,966)

Human mitochondrial malate dehydrogenase (United States Patent 6,274,138)

Compounds and methods for treating mitochondria-associated diseases (United States Patent 6,268,398)

Method and kit for measuring mitochondrial activity (United States Patent 6,261,796)

Composition for improvement of cellular nutrition and mitochondrial energetics (United States Patent 6,232,346)

Method for diagnosing preclinical diabetes by quantification of mitochondrial DNA in peripheral blood (United States Patent 6,232,078)

Bacterial expression systems based on plastic or mitochondrial promoter combinations (United States Patent 6,218,145)

Methods to identify compounds affecting mitochondria (United States Patent 6,183,948)

Method of targeting conjugate molecules to mitochondria (United States Patent 6,171,859)

Cellular models for diabetes and other diseases associated with mitochondrial defects (United States Patent 6,146,831)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,140,067)

Methods and compositions for the protection of mitochondria (United States Patent 6,103,746)

Method of protein production using mitochondrial translation system (United States Patent 6,100,068)

Composition for improvement of cellular nutrition and mitochondrial energetics (United States Patent 6,080,788)

Antisense inhibition of PEPCK-mitochondrial expression (United States Patent 6,030,837)

Optimal procedure for isolation of mutant mitochondrial alleles (United States Patent 6,027,883)

Polynucleotides encoding human mitochondrial chaperone proteins (United States Patent 6,010,879)

Mitochondrial processing peptidase subunit (United States Patent 6,001,629)

Mitochondrial adenylate kinase (United States Patent 6,001,624)

Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid (United States Patent 5,976,798)

Transgenic plants including a transgene consisting of a hybrid nucleic acid sequence, comprising at least one unedited mitochondrial gene fragment from higher plants and process for producing them (United States Patent 5,914,447)

Mutant gene causing a defect in mitochondrial recombination and a method for its detection (United States Patent 5,908,747)

Cellular and animal models for diseases associated with mitochondrial defects (United States Patent 5,888,498)

Mitochondrial processing peptidase subunit (United States Patent 5,869,311)

Mitochondrial adenylate kinase (United States Patent 5,856,160)

Human mitochondrial membrane protein (United States Patent 5,854,414)

Diagnostic agent for hypoxia or mitochondrial dysfunction comprising radioactive copper complex of dithiosemicarbazone derivative or diamine diol schiff base derivative (United States Patent 5,843,400)

Mitochondrial DNA mutations that segregate with late onset diabetes mellitus (United States Patent 5,840,493)

Species-specific mitochondrial sequences for identification of Tilletia indica, the karnal bunt wheat fungus and methods of using said sequences (United States Patent 5,811,240)

DNA sequence imparting cytoplasmic male sterility, mitochondrial genome, nuclear genome, mitochondria and plant containing said sequence and process for the preparation of hybrids (United States Patent 5,789,566)

Isolated nucleotide sequences corresponding to mitochondrial cytochrome oxidase genes (United States Patent 5,760,205)

Application of riluzole in the treatment of mitochondrial diseases (United States Patent 5,686,475)

Xanthylium dyes that are well retained in mitochondria (United States Patent 5,686,261)

Detection of mitochondrial DNA mutation 14459 associated with dystonia and/or Leber's hereditary optic neuropathy (United States Patent 5,670,320)

Mitochondrial P450 (United States Patent 5,668,000)

Maize cytoplasmic male sterility type T (cms-T) mitochondria DNA (United States Patent 5,660,983)

RNA import elements for transport into mitochondria (United States Patent 5,569,754)

Detection of mitochondrial DNA mutations associated with Alzheimer's disease and Parkinson's disease (United States Patent 5,494,794)

Xanthylium dyes that are well retained in mitochondria (United States Patent 5,459,268)

Association of bovine mitochondrial DNA with traits of economic importance (United States Patent 5,292,639)

Hybrid vector and process for improving the amplification and expression of hybrid vectors by the use of mitochondrial DNA (United States Patent 4,492,758)

Method for determination of cytoplasmatic and mitochondrial isoenzymes of glutamic-oxalacetic transaminase in human serum or plasma (United States Patent 4,477,566)

Mitochondrial creatine kinase antibody (United States Patent 7,148,063)

Culturable mitochondrial cells with no nucleus, showing mitochondrial activity (United States Patent 7,125,716)

Non-invasive diagnostic imaging technology for mitochondria dysfunction using radiolabeled lipophilic salts (United States Patent 7,112,318)

Mitochondrially targeted antioxidants (United States Patent 7,109,189)

Method for determining chum salmon haplotype using mitochondrial DNA (United States Patent 7,105,299)

Mimetics and inhibitors of the interaction between Vpr (HIV viral protein of regulation) and ANT (Mitochondrial adenine nucleotide translocator) (United States Patent 7,056,735)

Human mitochondrial proteins and polynucleotides encoding the proteins (United States Patent 7,026,452)

Mitochondrially targeted antioxidants (United States Patent 6,984,636)

Compositions and methods for treatment of mitochondrial diseases (United States Patent 6,956,028)

(1-phenyl-2-heteoaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase (United States Patent 6,916,813)

Method of targeting conjugate molecules to mitochondria (United States Patent 6,867,197)

Use of fumaric acid derivatives for treating mitochondrial diseases (United States Patent 6,858,750)

Simple and quick method for determining the nucleotide sequence of a mitochondrial 21S ribosomal RNA gene of yeast belonging to Saccharomyces cerevisiae (United States Patent 6,852,489)

N-substituted phenylurea inhibitors of mitochondrial F1F0 ATP hydrolase (United States Patent 6,846,836)

Compositions and methods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions (United States Patent 6,797,467)

Human mitochondrial proteins and polynucleotides encoding the same (United States Patent 6,790,667)

Method of detecting mitochondrial dysfunction (United States Patent 6,759,196)

Subtle mitochondrial mutations as tumor markers (United States Patent 6,750,021)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,653,094)

Mitochondrial dosimeter (United States Patent 6,605,433)

Methods to identify compounds affecting mitochondria (United States Patent 6,586,241)

Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions (United States Patent 6,562,563)

Compounds for altering mitochondrial function and cellular responses (United States Patent 6,552,076)

Mitochondria protecting agents for treating mitochondria associated diseases (United States Patent 6,511,966)

Mitochondria protecting agents for treating mitochondria associated diseases (United States Patent 6,498,191)

Transgenic plants including a transgene consisting of a hybrid nucleic acid sequence, comprising at least one unedited mitochondrial gene fragment from higher plants and process for producing them (United States Patent 6,479,735)

Methods and compositions for the protection of mitochondria (United States Patent 6,479,533)

Colorimetric test for agents that induce mitochondrial dysfunction (United States Patent 6,479,251)

Compositions and methods for treatment of mitochondrial diseases (United States Patent 6,472,378)

Nutritional assessment by measuring mitochondrial complex activity (United States Patent 6,455,243)

Human mitochondrial chaperone protein (United States Patent 6,432,915)

Mitochondrial membrane stabilizer (United States Patent 6,417,220)

Subtle mitochondrial mutations as tumor markers (United States Patent 6,344,322)

Mitochondrially targeted antioxidants (United States Patent 6,331,532)

Mitochondrial DNA damage as a predictor of coronary atherosclerotic heart disease (United States Patent 6,322,974)

Use of a compound with affinity for the mitochondrial benzodiazepine receptor in cancer therapy (United States Patent 6,319,931)

Drug mitochondrial targeting agents (United States Patent 6,316,652)

Cyanine dyes that stain cells and mitochondria (United States Patent 6,291,203)

Indicators of altered mitochondrial function in predictive methods for determining risk of type 2 diabetes mellitus (United States Patent 6,280,966)

Human mitochondrial malate dehydrogenase (United States Patent 6,274,138)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.