PATENTS RELATED TO PLASMIDS

Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of plasmids related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Plasmid maintenance system for antigen delivery (United States Patent 7,141,408)

Plasmid maintenance system for antigen delivery (United States Patent 7,138,112)

Promoter and plasmid system for genetic engineering (United States Patent 7,132,527)

Plasmid maintenance system for antigen delivery (United States Patent 7,125,720)

Fragment of L. lactis plasmid conferring antiphage activity and uses thereof (United States Patent 7,119,167)

Plasmids comprising nucleic acids from the hereditary hemochromatosis gene (United States Patent 7,078,513)

Ketogulonigenium endogenous plasmids (United States Patent 7,053,197)

Ketogulonigenium endogenous plasmids (United States Patent 7,053,196)

Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides (United States Patent 7,049,100)

Temperature sensitive mutant derivatives of the broad host range plasmid pBHR1 (United States Patent 7,045,338)

Methods for preparing yeast with improved biotin productivity using integrating plasmids encoding biotin synthase (United States Patent 7,033,814)

Ketogulonigenium endogeneous plasmids (United States Patent 7,030,233)

Plasmids for plant transformation and method for using the same (United States Patent 7,029,908)

Process and equipment for plasmid purification (United States Patent 7,026,468)

Recombinant DNA, plasmid, transformed microorganism and vaccine protein for prevention and therapy of urinary tract infection (United States Patent 7,001,744)

Plasmid maintenance system for antigen delivery (United States Patent 6,977,176)

Plasmid maintenance system for antigen delivery (United States Patent 6,969,513)

Recombinant plasmid and a method of controlling the effects of Yersinia pestis (United States Patent 6,964,770)

Fusobacterium nucleic acids, plasmids and vectors (United States Patent 6,962,990)

Plasmid vector comprising a retroviral integrase gene and an integrase recognition region (United States Patent 6,936,465)

Plasmid autonomously replicable in coryneform bacteria (United States Patent 6,905,819)

Plasmid originated from bifidobacterium, recombinant expression vector using the plasmid and transformation method (United States Patent 6,887,702)

DNA FRAGMENT CARRYING TOLUENE MONOOXYGENASE GENE, RECOMBINANT PLASMID, TRANSFORMED MICROORGANISM, METHOD FOR DEGRADING CHLORINATED ALIPHATIC HYDROCARBON COMPOUNDS AND AROMATIC COMPOUNDS, AND METHOD FOR ENVIRONMENTAL REMEDIATION (United States Patent 6,864,074)

DNA FRAGMENT CARRYING TOLUENE MONOOXYGENASE, GENE, RECOMBINANT PLASMID, TRANSFORMED MICROORGANISM, METHOD FOR DEGRADING CHLORINATED ALIPHATIC HYDROCARBON COMPOUNDS AND AROMATIC COMPOUNDS, AND METHOD FOR ENVIRONMENTAL REMEDIATION (United States Patent 6,858,417)

Recombinant plasmid pDSBCm, microorganisms transformed therewith, and method for producing an alkaline protease VapK (United States Patent 6,858,408)

Plasmid DNA containing reporter gene DNA and use of the same (United States Patent 6,855,543)

Plasmid-based vaccine for treating atherosclerosis (United States Patent 6,846,808)

Plasmids and methods for monitoring endonuclease digestion efficiency (United States Patent 6,828,102)

Vectors for improving cloning and expression in low copy number plasmids (United States Patent 6,818,441)

Method for construction of Thermus-E, coli shuttle vectors and identification of two thermus plasmid replication origins (United States Patent 6,815,537)

Methods for encapsulating plasmids in lipid bilayers (United States Patent 6,815,432)

DNA sequences for an amino acid transporter plasmids, bacteria, yeasts and plants containing a transporter and their use (United States Patent 6,809,233)

Expression vectors with modified ColE1 origin of replication for control of plasmid copy number (United States Patent 6,806,066)

Trehalose synthase protein, gene, plasmids, microorganisms, and a process for producing trehalose (United States Patent 6,800,474)

Process for the scaleable purification of plasmid DNA (United States Patent 6,797,476)

Plasmids from Corynebacterium glutamicum and use thereof (United States Patent 6,777,229)

Method of plasmid recovery and apparatus for doing so (United States Patent 6,759,233)

Plasmid stabilization (United States Patent 6,743,780)

Purification of plasmid DNA of pharmaceutical quality (United States Patent 6,730,781)

Avoidance of undesirable replication intermediates in plasmid propagation (United States Patent 6,709,844)

Plasmid DNA from Yersinia pestis (United States Patent 6,706,522)

Plasmid maintenance system for antigen delivery (United States Patent 6,703,233)

MURINE .alpha. (1,3) FUCOSYLTRANSFERASE FUC-TVII, DNA ENCODING THE SAME, METHOD FOR PREPARING THE SAME, ANTIBODIES RECOGNIZING THE SAME, IMMUNOASSAYS FOR DETECTING THE SAME, PLASMIDS CONTAINING SUCH DNA, AND CELLS CONTAINING SUCH A PLASMID (United States Patent 6,693,183)

DsbA/DsbB/DsbC/DsbD expression plasmid (United States Patent 6,673,569)

Expression cassette and plasmid for strong constitutive gene expression and the use thereof (United States Patent 6,664,387)

Transformation system with Ti or Ri plasmid (United States Patent 6,664,109)

Method for the isolation of ccc plasmid DNA (United States Patent 6,664,078)

Plasmid for gene expression in pichia ciferrii and transformation method using the same (United States Patent 6,638,735)

Recombinant plasmid and a method of controlling the effects of Yersinia pestis (United States Patent 6,638,510)

DNA sequence from Arabidopsis thaliana encoding ammonium transporter, and plasmids, bacteria and yeast comprising the DNA sequence (United States Patent 6,620,610)

Fluorescence-labeled probe for DNA and a fluorescence-labeled plasmid (United States Patent 6,608,213)

Vaccines against infections caused by YF virus; YF infectious cDNA, method for producing a recombinant YF virus from the YF infectious cDNA and plasmids to assemble the YF infectious cDNA (United States Patent 6,589,522)

Temperature sensitive plasmids of P. haemolytica (United States Patent 6,573,093)

Isolated nucleic acids from Micromonospora rosaria plasmid pMR2 and vectors made therefrom (United States Patent 6,569,668)

Bacterial plasmid having genes encoding enzymes for the degradation of aromatic compounds (United States Patent 6,548,292)

Method of isolating plasmid DNA (United States Patent 6,548,253)

Methods for encapsulating plasmids in lipid bilayers (United States Patent 6,534,484)

Non RCR leuconostoc plasmid capable of being transferred into lactic acid bacteria, use as cloning and expressing tool (United States Patent 6,528,285)

Plasmids, their construction and their use in the manufacture of interleukin-4 and interleukin-4 muteins (United States Patent 6,506,590)

Endogenous ketogulonigenium plasmid (United States Patent 6,503,748)

Method of plasmid DNA production and purification (United States Patent 6,503,738)

DNA sequences which lead to the formation of polyfructans (levans), plasmids containing these sequences as well as a process for preparing transgenic plants (United States Patent 6,501,005)

Genomic sequence of Rhizobium sp. NGR 234 symbiotic plasmid (United States Patent 6,475,793)

Plasmids for construction of eukaryotic viral vectors (United States Patent 6,475,757)

Plasmid-based mutation detection system in transgenic fish (United States Patent 6,472,583)

DNA FRAGMENT CARRYING TOLUENE MONOOXYGENASE GENE, RECOMBINANT PLASMID, TRANSFORMED MICROORGANISM, METHOD FOR DEGRADING CHLORINATED ALIPHATIC HYDROCARBON COMPOUNDS AND AROMATIC COMPOUNDS, AND METHOD FOR ENVIRONMENTAL REMEDIATION (United States Patent 6,472,191)

Drawing template for plasmid DNA (United States Patent 6,460,267)

Mechanical disruption of bacterial cells for plasmid recovery (United States Patent 6,455,287)

Separating plasmids from contaminants using hydrophobic or hydrophobic and ion exchange chromatography (United States Patent 6,441,160)

Tryparedoxin, expression plasmid, process of production, method of use, test kit, and pharmaceutical composition (United States Patent 6,432,671)

Plasmid encoding a modified steroid hormone (United States Patent 6,416,998)

Expression plasmids (United States Patent 6,413,768)

Plasmid DNA purification using divalent alkaline earth metal ions and two anion exchangers (United States Patent 6,410,274)

Method for preparing plasmids, and uses related thereto (United States Patent 6,410,244)

Acetate-free purification of plasmid DNA on hydroxyapatite (United States Patent 6,406,892)

Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides (United States Patent 6,399,789)

Cancer treatment method utilizing plasmids suitable for IL-2 expression (United States Patent 6,399,588)

Vector derivatives of gluconobacter plasmid pF4 (United States Patent 6,399,340)

Bacterial plasmids (United States Patent 6,391,631)

Plasmids that encode green fluorescent protein (United States Patent 6,391,630)

Polymerase I promoter plasmid and vector constructs (United States Patent 6,368,862)

Plasmids originating in ammonia oxidizing bacteria and use of the same (United States Patent 6,350,577)

Hybrid genes incorporating a DNA fragment containing at least one gene encoding an insecticidal protein and a gene encoding a glutamine synthase inhibitor, plasmids, transformed cyanobacteria expressing such proteins and method for use as biocontrol agent (United States Patent 6,335,008)

Plasmids for construction of eukaryotic viral vectors (United States Patent 6,329,200)

Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals (United States Patent 6,316,004)

Purification of plasmid DNA (United States Patent 6,313,285)

Temperature sensitive plasmid for coryneform bacteria (United States Patent 6,303,383)

Plasmids comprising a genetically altered feline immunodeficiency virus genome (United States Patent 6,300,118)

Plasmid-derived llad II restriction-modification system from lactococcus lactis (United States Patent 6,300,109)

Replication genes and gene products from small cryptic plasmids and methods for constructing controlled-replication plasmid vectors (United States Patent 6,294,372)

Plasmid-based vaccine for treating atherosclerosis (United States Patent 6,284,533)

Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities (United States Patent 6,280,986)

Strain E. coli JM83/pKP2 transformed with a recombi plasmid and phytase produced therefrom (United States Patent 6,277,623)

Plasmids without a selection marker gene (United States Patent 6,265,218)

Expression vectors based on RK2 and TOL plasmids (United States Patent 6,258,565)

Recombinant eukaryotic plasmids containing allergen-gene and use thereof for the prevention and/or treatment of allergic diseases (United States Patent 6,251,663)

Immunization with plasmid encoding immunogenic proteins and intracellular targeting sequences (United States Patent 6,248,565)

DNA sequences for an arabidopsis amino acid transporter, plasmids, bacteria, yeasts and plants containing a transporter and their use (United States Patent 6,245,970)

Plasmids encoding immunogenic proteins and intracellular targeting sequences (United States Patent 6,228,621)

Plasmid maintenance system for antigen delivery (United States Patent 7,141,408)

Plasmid maintenance system for antigen delivery (United States Patent 7,138,112)

Promoter and plasmid system for genetic engineering (United States Patent 7,132,527)

Plasmid maintenance system for antigen delivery (United States Patent 7,125,720)

Fragment of L. lactis plasmid conferring antiphage activity and uses thereof (United States Patent 7,119,167)

Plasmids comprising nucleic acids from the hereditary hemochromatosis gene (United States Patent 7,078,513)

Ketogulonigenium endogenous plasmids (United States Patent 7,053,197)

Ketogulonigenium endogenous plasmids (United States Patent 7,053,196)

Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides (United States Patent 7,049,100)

Temperature sensitive mutant derivatives of the broad host range plasmid pBHR1 (United States Patent 7,045,338)

Methods for preparing yeast with improved biotin productivity using integrating plasmids encoding biotin synthase (United States Patent 7,033,814)

Ketogulonigenium endogeneous plasmids (United States Patent 7,030,233)

Plasmids for plant transformation and method for using the same (United States Patent 7,029,908)

Process and equipment for plasmid purification (United States Patent 7,026,468)

Recombinant DNA, plasmid, transformed microorganism and vaccine protein for prevention and therapy of urinary tract infection (United States Patent 7,001,744)

Plasmid maintenance system for antigen delivery (United States Patent 6,977,176)

Plasmid maintenance system for antigen delivery (United States Patent 6,969,513)

Recombinant plasmid and a method of controlling the effects of Yersinia pestis (United States Patent 6,964,770)

Fusobacterium nucleic acids, plasmids and vectors (United States Patent 6,962,990)

Plasmid vector comprising a retroviral integrase gene and an integrase recognition region (United States Patent 6,936,465)

Plasmid autonomously replicable in coryneform bacteria (United States Patent 6,905,819)

Plasmid originated from bifidobacterium, recombinant expression vector using the plasmid and transformation method (United States Patent 6,887,702)

DNA FRAGMENT CARRYING TOLUENE MONOOXYGENASE GENE, RECOMBINANT PLASMID, TRANSFORMED MICROORGANISM, METHOD FOR DEGRADING CHLORINATED ALIPHATIC HYDROCARBON COMPOUNDS AND AROMATIC COMPOUNDS, AND METHOD FOR ENVIRONMENTAL REMEDIATION (United States Patent 6,864,074)

DNA FRAGMENT CARRYING TOLUENE MONOOXYGENASE, GENE, RECOMBINANT PLASMID, TRANSFORMED MICROORGANISM, METHOD FOR DEGRADING CHLORINATED ALIPHATIC HYDROCARBON COMPOUNDS AND AROMATIC COMPOUNDS, AND METHOD FOR ENVIRONMENTAL REMEDIATION (United States Patent 6,858,417)

Recombinant plasmid pDSBCm, microorganisms transformed therewith, and method for producing an alkaline protease VapK (United States Patent 6,858,408)

Plasmid DNA containing reporter gene DNA and use of the same (United States Patent 6,855,543)

Plasmid-based vaccine for treating atherosclerosis (United States Patent 6,846,808)

Plasmids and methods for monitoring endonuclease digestion efficiency (United States Patent 6,828,102)

Vectors for improving cloning and expression in low copy number plasmids (United States Patent 6,818,441)

Method for construction of Thermus-E, coli shuttle vectors and identification of two thermus plasmid replication origins (United States Patent 6,815,537)

Methods for encapsulating plasmids in lipid bilayers (United States Patent 6,815,432)

DNA sequences for an amino acid transporter plasmids, bacteria, yeasts and plants containing a transporter and their use (United States Patent 6,809,233)

Expression vectors with modified ColE1 origin of replication for control of plasmid copy number (United States Patent 6,806,066)

Trehalose synthase protein, gene, plasmids, microorganisms, and a process for producing trehalose (United States Patent 6,800,474)

Process for the scaleable purification of plasmid DNA (United States Patent 6,797,476)

Plasmids from Corynebacterium glutamicum and use thereof (United States Patent 6,777,229)

Method of plasmid recovery and apparatus for doing so (United States Patent 6,759,233)

Plasmid stabilization (United States Patent 6,743,780)

Purification of plasmid DNA of pharmaceutical quality (United States Patent 6,730,781)

Avoidance of undesirable replication intermediates in plasmid propagation (United States Patent 6,709,844)

Plasmid DNA from Yersinia pestis (United States Patent 6,706,522)

Plasmid maintenance system for antigen delivery (United States Patent 6,703,233)

MURINE .alpha. (1,3) FUCOSYLTRANSFERASE FUC-TVII, DNA ENCODING THE SAME, METHOD FOR PREPARING THE SAME, ANTIBODIES RECOGNIZING THE SAME, IMMUNOASSAYS FOR DETECTING THE SAME, PLASMIDS CONTAINING SUCH DNA, AND CELLS CONTAINING SUCH A PLASMID (United States Patent 6,693,183)

DsbA/DsbB/DsbC/DsbD expression plasmid (United States Patent 6,673,569)

Expression cassette and plasmid for strong constitutive gene expression and the use thereof (United States Patent 6,664,387)

Transformation system with Ti or Ri plasmid (United States Patent 6,664,109)

Method for the isolation of ccc plasmid DNA (United States Patent 6,664,078)

Plasmid for gene expression in pichia ciferrii and transformation method using the same (United States Patent 6,638,735)

Recombinant plasmid and a method of controlling the effects of Yersinia pestis (United States Patent 6,638,510)

DNA sequence from Arabidopsis thaliana encoding ammonium transporter, and plasmids, bacteria and yeast comprising the DNA sequence (United States Patent 6,620,610)

Fluorescence-labeled probe for DNA and a fluorescence-labeled plasmid (United States Patent 6,608,213)

Vaccines against infections caused by YF virus; YF infectious cDNA, method for producing a recombinant YF virus from the YF infectious cDNA and plasmids to assemble the YF infectious cDNA (United States Patent 6,589,522)

Temperature sensitive plasmids of P. haemolytica (United States Patent 6,573,093)

Isolated nucleic acids from Micromonospora rosaria plasmid pMR2 and vectors made therefrom (United States Patent 6,569,668)

Bacterial plasmid having genes encoding enzymes for the degradation of aromatic compounds (United States Patent 6,548,292)

Method of isolating plasmid DNA (United States Patent 6,548,253)

Methods for encapsulating plasmids in lipid bilayers (United States Patent 6,534,484)

Non RCR leuconostoc plasmid capable of being transferred into lactic acid bacteria, use as cloning and expressing tool (United States Patent 6,528,285)

Plasmids, their construction and their use in the manufacture of interleukin-4 and interleukin-4 muteins (United States Patent 6,506,590)

Endogenous ketogulonigenium plasmid (United States Patent 6,503,748)

Method of plasmid DNA production and purification (United States Patent 6,503,738)

DNA sequences which lead to the formation of polyfructans (levans), plasmids containing these sequences as well as a process for preparing transgenic plants (United States Patent 6,501,005)

Genomic sequence of Rhizobium sp. NGR 234 symbiotic plasmid (United States Patent 6,475,793)

Plasmids for construction of eukaryotic viral vectors (United States Patent 6,475,757)

Plasmid-based mutation detection system in transgenic fish (United States Patent 6,472,583)

DNA FRAGMENT CARRYING TOLUENE MONOOXYGENASE GENE, RECOMBINANT PLASMID, TRANSFORMED MICROORGANISM, METHOD FOR DEGRADING CHLORINATED ALIPHATIC HYDROCARBON COMPOUNDS AND AROMATIC COMPOUNDS, AND METHOD FOR ENVIRONMENTAL REMEDIATION (United States Patent 6,472,191)

Drawing template for plasmid DNA (United States Patent 6,460,267)

Mechanical disruption of bacterial cells for plasmid recovery (United States Patent 6,455,287)

Separating plasmids from contaminants using hydrophobic or hydrophobic and ion exchange chromatography (United States Patent 6,441,160)

Tryparedoxin, expression plasmid, process of production, method of use, test kit, and pharmaceutical composition (United States Patent 6,432,671)

Plasmid encoding a modified steroid hormone (United States Patent 6,416,998)

Expression plasmids (United States Patent 6,413,768)

Plasmid DNA purification using divalent alkaline earth metal ions and two anion exchangers (United States Patent 6,410,274)

Method for preparing plasmids, and uses related thereto (United States Patent 6,410,244)

Acetate-free purification of plasmid DNA on hydroxyapatite (United States Patent 6,406,892)

Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides (United States Patent 6,399,789)

Cancer treatment method utilizing plasmids suitable for IL-2 expression (United States Patent 6,399,588)

Vector derivatives of gluconobacter plasmid pF4 (United States Patent 6,399,340)

Bacterial plasmids (United States Patent 6,391,631)

Plasmids that encode green fluorescent protein (United States Patent 6,391,630)

Polymerase I promoter plasmid and vector constructs (United States Patent 6,368,862)

Plasmids originating in ammonia oxidizing bacteria and use of the same (United States Patent 6,350,577)

Hybrid genes incorporating a DNA fragment containing at least one gene encoding an insecticidal protein and a gene encoding a glutamine synthase inhibitor, plasmids, transformed cyanobacteria expressing such proteins and method for use as biocontrol agent (United States Patent 6,335,008)

Plasmids for construction of eukaryotic viral vectors (United States Patent 6,329,200)

Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals (United States Patent 6,316,004)

Purification of plasmid DNA (United States Patent 6,313,285)

Temperature sensitive plasmid for coryneform bacteria (United States Patent 6,303,383)

Plasmids comprising a genetically altered feline immunodeficiency virus genome (United States Patent 6,300,118)

Plasmid-derived llad II restriction-modification system from lactococcus lactis (United States Patent 6,300,109)

Replication genes and gene products from small cryptic plasmids and methods for constructing controlled-replication plasmid vectors (United States Patent 6,294,372)

Plasmid-based vaccine for treating atherosclerosis (United States Patent 6,284,533)

Stabilization of pet operon plasmids and ethanol production in bacterial strains lacking lactate dehydrogenase and pyruvate formate lyase activities (United States Patent 6,280,986)

Strain E. coli JM83/pKP2 transformed with a recombi plasmid and phytase produced therefrom (United States Patent 6,277,623)

Plasmids without a selection marker gene (United States Patent 6,265,218)

Expression vectors based on RK2 and TOL plasmids (United States Patent 6,258,565)

Recombinant eukaryotic plasmids containing allergen-gene and use thereof for the prevention and/or treatment of allergic diseases (United States Patent 6,251,663)

Immunization with plasmid encoding immunogenic proteins and intracellular targeting sequences (United States Patent 6,248,565)

DNA sequences for an arabidopsis amino acid transporter, plasmids, bacteria, yeasts and plants containing a transporter and their use (United States Patent 6,245,970)

Plasmids encoding immunogenic proteins and intracellular targeting sequences (United States Patent 6,228,621)

Plasmid maintenance system for antigen delivery (United States Patent 7,141,408)

Plasmid maintenance system for antigen delivery (United States Patent 7,138,112)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.