PATENTS RELATED TO SERUM

Although Dr. Demchick also represents patent seekers with non-biological inventions, his doctorate is in biology. Biology has been the primary focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biology.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.

If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.

The following sampling is to give you some sense of the types of serum related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.

It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Method of concentrating proteins from serum (United States Patent 7,151,000)

Assessment of liver fibrosis scoring with serum marker algorithms (United States Patent 7,141,380)

FXIII detection for verifying serum sample and sample size and for detecting dilution (United States Patent 7,141,362)

FXIII detection for verifying serum sample and sample size and for detecting dilution (United States Patent 7,138,245)

Serum-free medium for mesenchymal stem cells (United States Patent 7,109,032)

Use of dual conjugated labels in the elimination of serum interference in immunochromatographic assays (United States Patent 7,108,993)

Antibody-serum protein hybrids (United States Patent 7,105,160)

Erythropoietin analog-human serum albumin fusion (United States Patent 7,101,971)

Composition for blood serum or plasma separation and vessel for blood examination containing the same (United States Patent 7,090,970)

Method for the crystallization of human serum albumin (United States Patent 7,087,719)

Growth of human Mesenchymal Stem Cells (hMSC) using umbilical cord blood serum and the method for the preparation thereof (United States Patent 7,060,494)

.beta.-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same (United States Patent 7,045,515)

Recombinant fusion proteins to growth hormone and serum albumin (United States Patent 7,045,318)

Method for the chromatographic fractionation of plasma or serum, preparations, so obtained, and their use (United States Patent 7,041,798)

Cell culture system for determining the cholesterol efflux potential for serum (United States Patent 7,029,863)

Serum paraoxonase (United States Patent 7,026,140)

Plasma- or serum-collecting device (United States Patent 7,025,212)

Method for increasing the serum half-life of a biologically active molecule (United States Patent 7,022,673)

Method for the simultaneous and direct determination of serum cholesterol in high and low density lipoproteins using infrared spectroscopy (United States Patent 7,022,527)

Compositions and methods for reducing serum glucose and triglyceride levels in diabetic mammals (United States Patent 7,019,034)

Serum free cultivation of primate embryonic stem cells (United States Patent 7,005,252)

Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 7,002,030)

Method for removing multimers of human serum albumin (United States Patent 7,001,885)

Nutritional supplement for lowering serum triglyceride and cholesterol levels (United States Patent 6,998,501)

Method of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substitute indolealkanoic acids (United States Patent 6,964,980)

Immortalized human skin cell lines and novel serum-free medium useful for the production thereof (United States Patent 6,949,381)

Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays (United States Patent 6,939,675)

Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer (United States Patent 6,939,671)

5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity (United States Patent 6,936,636)

Method for reducing non-specific aggregation of latex microparticles in the presence of serum or plasma (United States Patent 6,927,071)

Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer (United States Patent 6,916,634)

Method for preparing human serum albumin containing heat-treatment (United States Patent 6,908,749)

Detection of antibodies to squalene in serum (United States Patent 6,900,025)

7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,887,896)

5,6,7,8-tetrahydronaphthalen-2-yl-7-fluoroalkyl-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,884,820)

Method for detecting .alpha.-oxoaldehydes in the whole blood, blood plasma and/or serum of a patient (United States Patent 6,884,223)

Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof (United States Patent 6,878,514)

Serum transfer cup (United States Patent 6,878,346)

Method for assessing the risk of peptic ulcer, comprising the steps of determining quantitatively the concentrations of pepsinogen I (PGI) and gastrin-17 in a serum sample (United States Patent 6,872,543)

Control serum for dry analytical element (United States Patent 6,852,540)

Serum-free cell culture media (United States Patent 6,833,271)

Process for the purification of serum albumin (United States Patent 6,831,157)

Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell (United States Patent 6,825,036)

Detection of metabolic dysfunctions using fluorescence emission from serum (United States Patent 6,813,009)

Fetuin-MGP-mineral complex in serum assayed to determine calcification risk (United States Patent 6,812,034)

Polypeptides that inhibit human serum-induced cleavage of hepatocyte growth factor (United States Patent 6,800,604)

Method for detection of 5T4 RNA in plasma or serum (United States Patent 6,794,135)

Modified serum albumin with reduced affinity for nickel and copper (United States Patent 6,787,636)

Serum-derived factor inducing cell differentiation and medical uses thereof (United States Patent 6,783,775)

Intra-serum and intra-gel for modeling human skin tissue (United States Patent 6,777,240)

Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,770,768)

5,6,7,8-tetrahydronaphthalen-2-yl 2,6-difluoroheptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,759,547)

3,5-di-iso-propyl-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,759,546)

Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer (United States Patent 6,759,217)

Circulating epstein-barr virus DNA in the serum of patients with gastric carcinoma (United States Patent 6,753,137)

Use of human serum resistant vector particles and cell lines for human gene therapy (United States Patent 6,743,631)

Direct serum lipids assays for evaluation of disease states (United States Patent 6,737,275)

(1,2,3,4-tetrahydroquinolin-8-yl)-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,734,193)

Compositions and methods for modulating serum cholesterol (United States Patent 6,713,057)

Preparation of virally inactivated intravenously injectable immune serum globulin (United States Patent 6,686,191)

Fusion polypeptides of human serum albumin and a therapeutically active polypeptide (United States Patent 6,686,179)

Method for identification of cellular protein antigens and presence of antibodies to specific cellular protein antigens in serum (United States Patent 6,677,128)

FXIII detection for verifying serum sample and sample size and for detecting dilution (United States Patent 6,660,486)

Plasma- or serum-collecting device (United States Patent 6,659,288)

Serum-free, low-protein media for rotavirus vaccine production (United States Patent 6,656,719)

Annexin proteins and autoantibodies as serum markers for cancer (United States Patent 6,645,465)

Nuclear transfer using cells cultured in serum starvation media containing apoptosis inhibitors (United States Patent 6,635,802)

Detection of extracellular tumor-associated nucleic acid in blood plasma or serum (United States Patent 6,630,301)

Increasing the HDL level and the HDL/LDL ratio in human serum by balancing saturated and polyunsaturated dietary fatty acids (United States Patent 6,630,192)

Device and method for preliminary testing a neat serum sample in a primary collection tube (United States Patent 6,628,395)

Automated method for detecting, quantifying and monitoring exogenous hemoglobin in whole blood, plasma and serum (United States Patent 6,623,972)

Method of determining presence and concentration of lipoprotein X in blood plasma and serum (United States Patent 6,617,167)

Serum-free cell growth medium (United States Patent 6,617,161)

Serum free medium for chondrocyte cells (United States Patent 6,617,159)

Process for purifying recombinant human serum albumin (United States Patent 6,617,133)

Method for the removal/purification of serum albumins and means for use in the method (United States Patent 6,613,884)

Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum (United States Patent 6,607,898)

Cosmetic intensive repair serum with morinda citrifolia (United States Patent 6,589,514)

METHOD OF DIAGNOSING IRRITABLE BOWEL SYNDROME AND OTHER DISORDERS CAUSED BY SMALL INTESTINAL BACTERIAL OVERGROWTH BY DETECTING THE PRESENCE OF ANTI-SACCHAROMYCES CERIVISIAE ANTIBODIES (ASCA) IN HUMAN SERUM (United States Patent 6,562,629)

Media for culturing human cells comprising human serum and method for culturing human cells using the same (United States Patent 6,558,949)

Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids (United States Patent 6,555,568)

Erythropoietin analog-human serum albumin fusion (United States Patent 6,548,653)

Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,544,973)

Method for the visual detection of specific antibodies in human serum by the use of lateral flow assays (United States Patent 6,528,325)

Recombinant human serum transferrins containing peptides for inducing apoptosis in HIV-1 infected cells (United States Patent 6,528,287)

Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays (United States Patent 6,521,409)

Methods for detecting papillomavirus DNA in blood plasma and serum (United States Patent 6,511,805)

Immunoassay for quantification of C-terminal telopeptides of type I collagen in human serum (United States Patent 6,509,450)

Serum amyloid a isoform from colostrum (United States Patent 6,509,444)

Serum-and steroid-free culture media for cerebellar granule neurons (United States Patent 6,506,576)

Process for the purification of serum albumin (United States Patent 6,504,011)

Intra-serum and intra-gel for modeling human skin tissue (United States Patent 6,475,800)

Method for detection of prostate specific membrane antigen in serum (United States Patent 6,475,389)

Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes (United States Patent 6,470,279)

Method for determining drug-serum protein binding (United States Patent 6,468,757)

Detection of loss of heterozygosity in tumor and serum of melanoma patients (United States Patent 6,465,177)

Diagnostic imaging contrast agent with improved in serum relaxivity (United States Patent 6,458,337)

Antisense modulation of serum amyloid A4 expression (United States Patent 6,455,308)

pH-sensitive, serum-stable liposomes (United States Patent 6,426,086)

Method of concentrating proteins from serum (United States Patent 7,151,000)

Assessment of liver fibrosis scoring with serum marker algorithms (United States Patent 7,141,380)

FXIII detection for verifying serum sample and sample size and for detecting dilution (United States Patent 7,141,362)

FXIII detection for verifying serum sample and sample size and for detecting dilution (United States Patent 7,138,245)

Serum-free medium for mesenchymal stem cells (United States Patent 7,109,032)

Use of dual conjugated labels in the elimination of serum interference in immunochromatographic assays (United States Patent 7,108,993)

Antibody-serum protein hybrids (United States Patent 7,105,160)

Erythropoietin analog-human serum albumin fusion (United States Patent 7,101,971)

Composition for blood serum or plasma separation and vessel for blood examination containing the same (United States Patent 7,090,970)

Method for the crystallization of human serum albumin (United States Patent 7,087,719)

Growth of human Mesenchymal Stem Cells (hMSC) using umbilical cord blood serum and the method for the preparation thereof (United States Patent 7,060,494)

.beta.-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same (United States Patent 7,045,515)

Recombinant fusion proteins to growth hormone and serum albumin (United States Patent 7,045,318)

Method for the chromatographic fractionation of plasma or serum, preparations, so obtained, and their use (United States Patent 7,041,798)

Cell culture system for determining the cholesterol efflux potential for serum (United States Patent 7,029,863)

Serum paraoxonase (United States Patent 7,026,140)

Plasma- or serum-collecting device (United States Patent 7,025,212)

Method for increasing the serum half-life of a biologically active molecule (United States Patent 7,022,673)

Method for the simultaneous and direct determination of serum cholesterol in high and low density lipoproteins using infrared spectroscopy (United States Patent 7,022,527)

Compositions and methods for reducing serum glucose and triglyceride levels in diabetic mammals (United States Patent 7,019,034)

Serum free cultivation of primate embryonic stem cells (United States Patent 7,005,252)

Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 7,002,030)

Method for removing multimers of human serum albumin (United States Patent 7,001,885)

Nutritional supplement for lowering serum triglyceride and cholesterol levels (United States Patent 6,998,501)

Method of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substitute indolealkanoic acids (United States Patent 6,964,980)

Immortalized human skin cell lines and novel serum-free medium useful for the production thereof (United States Patent 6,949,381)

Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays (United States Patent 6,939,675)

Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer (United States Patent 6,939,671)

5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity (United States Patent 6,936,636)

Method for reducing non-specific aggregation of latex microparticles in the presence of serum or plasma (United States Patent 6,927,071)

Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer (United States Patent 6,916,634)

Method for preparing human serum albumin containing heat-treatment (United States Patent 6,908,749)

Detection of antibodies to squalene in serum (United States Patent 6,900,025)

7-[(7-Alkoxy)-chrom-3-en-6-yl]-heptatrienoic acid and 7-[(3-alkoxy)-5,6-dihydronaphthalen-2-yl]-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,887,896)

5,6,7,8-tetrahydronaphthalen-2-yl-7-fluoroalkyl-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,884,820)

Method for detecting .alpha.-oxoaldehydes in the whole blood, blood plasma and/or serum of a patient (United States Patent 6,884,223)

Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof (United States Patent 6,878,514)

Serum transfer cup (United States Patent 6,878,346)

Method for assessing the risk of peptic ulcer, comprising the steps of determining quantitatively the concentrations of pepsinogen I (PGI) and gastrin-17 in a serum sample (United States Patent 6,872,543)

Control serum for dry analytical element (United States Patent 6,852,540)

Serum-free cell culture media (United States Patent 6,833,271)

Process for the purification of serum albumin (United States Patent 6,831,157)

Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell (United States Patent 6,825,036)

Detection of metabolic dysfunctions using fluorescence emission from serum (United States Patent 6,813,009)

Fetuin-MGP-mineral complex in serum assayed to determine calcification risk (United States Patent 6,812,034)

Polypeptides that inhibit human serum-induced cleavage of hepatocyte growth factor (United States Patent 6,800,604)

Method for detection of 5T4 RNA in plasma or serum (United States Patent 6,794,135)

Modified serum albumin with reduced affinity for nickel and copper (United States Patent 6,787,636)

Serum-derived factor inducing cell differentiation and medical uses thereof (United States Patent 6,783,775)

Intra-serum and intra-gel for modeling human skin tissue (United States Patent 6,777,240)

Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,770,768)

5,6,7,8-tetrahydronaphthalen-2-yl 2,6-difluoroheptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,759,547)

3,5-di-iso-propyl-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,759,546)

Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer (United States Patent 6,759,217)

Circulating epstein-barr virus DNA in the serum of patients with gastric carcinoma (United States Patent 6,753,137)

Use of human serum resistant vector particles and cell lines for human gene therapy (United States Patent 6,743,631)

Direct serum lipids assays for evaluation of disease states (United States Patent 6,737,275)

(1,2,3,4-tetrahydroquinolin-8-yl)-heptatrienoic acid derivatives having serum glucose reducing activity (United States Patent 6,734,193)

Compositions and methods for modulating serum cholesterol (United States Patent 6,713,057)

Preparation of virally inactivated intravenously injectable immune serum globulin (United States Patent 6,686,191)

Fusion polypeptides of human serum albumin and a therapeutically active polypeptide (United States Patent 6,686,179)

Method for identification of cellular protein antigens and presence of antibodies to specific cellular protein antigens in serum (United States Patent 6,677,128)

FXIII detection for verifying serum sample and sample size and for detecting dilution (United States Patent 6,660,486)

Plasma- or serum-collecting device (United States Patent 6,659,288)

Serum-free, low-protein media for rotavirus vaccine production (United States Patent 6,656,719)

Annexin proteins and autoantibodies as serum markers for cancer (United States Patent 6,645,465)

Nuclear transfer using cells cultured in serum starvation media containing apoptosis inhibitors (United States Patent 6,635,802)

Detection of extracellular tumor-associated nucleic acid in blood plasma or serum (United States Patent 6,630,301)

Increasing the HDL level and the HDL/LDL ratio in human serum by balancing saturated and polyunsaturated dietary fatty acids (United States Patent 6,630,192)

Device and method for preliminary testing a neat serum sample in a primary collection tube (United States Patent 6,628,395)

Automated method for detecting, quantifying and monitoring exogenous hemoglobin in whole blood, plasma and serum (United States Patent 6,623,972)

Method of determining presence and concentration of lipoprotein X in blood plasma and serum (United States Patent 6,617,167)

Serum-free cell growth medium (United States Patent 6,617,161)

Serum free medium for chondrocyte cells (United States Patent 6,617,159)

Process for purifying recombinant human serum albumin (United States Patent 6,617,133)

Method for the removal/purification of serum albumins and means for use in the method (United States Patent 6,613,884)

Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum (United States Patent 6,607,898)

Cosmetic intensive repair serum with morinda citrifolia (United States Patent 6,589,514)

METHOD OF DIAGNOSING IRRITABLE BOWEL SYNDROME AND OTHER DISORDERS CAUSED BY SMALL INTESTINAL BACTERIAL OVERGROWTH BY DETECTING THE PRESENCE OF ANTI-SACCHAROMYCES CERIVISIAE ANTIBODIES (ASCA) IN HUMAN SERUM (United States Patent 6,562,629)

Media for culturing human cells comprising human serum and method for culturing human cells using the same (United States Patent 6,558,949)

Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids (United States Patent 6,555,568)

Erythropoietin analog-human serum albumin fusion (United States Patent 6,548,653)

Substance for lowering high cholesterol level in serum and methods for preparing and using the same (United States Patent 6,544,973)

Method for the visual detection of specific antibodies in human serum by the use of lateral flow assays (United States Patent 6,528,325)

Recombinant human serum transferrins containing peptides for inducing apoptosis in HIV-1 infected cells (United States Patent 6,528,287)

Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays (United States Patent 6,521,409)

Methods for detecting papillomavirus DNA in blood plasma and serum (United States Patent 6,511,805)

Immunoassay for quantification of C-terminal telopeptides of type I collagen in human serum (United States Patent 6,509,450)

Serum amyloid a isoform from colostrum (United States Patent 6,509,444)

Serum-and steroid-free culture media for cerebellar granule neurons (United States Patent 6,506,576)

Process for the purification of serum albumin (United States Patent 6,504,011)

Intra-serum and intra-gel for modeling human skin tissue (United States Patent 6,475,800)

Method for detection of prostate specific membrane antigen in serum (United States Patent 6,475,389)

Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes (United States Patent 6,470,279)

Method for determining drug-serum protein binding (United States Patent 6,468,757)

Detection of loss of heterozygosity in tumor and serum of melanoma patients (United States Patent 6,465,177)

Diagnostic imaging contrast agent with improved in serum relaxivity (United States Patent 6,458,337)

Antisense modulation of serum amyloid A4 expression (United States Patent 6,455,308)

pH-sensitive, serum-stable liposomes (United States Patent 6,426,086)

Method of concentrating proteins from serum (United States Patent 7,151,000)

Assessment of liver fibrosis scoring with serum marker algorithms (United States Patent 7,141,380)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.