PATENTS RELATED TO UBIQUITIN

Professor Demchick's Patent Services

Paul H. Demchick, United States Registered Patent Agent
(United States Patent and Trademark Office Registration 52,808)

PATENTS RELATED TO UBIQUITIN

Although Dr. Demchick also represents patent seekers with non-biochemical inventions, his Ph.D. is in microbiology (with a minor in biochemistry), his M.A. is in biology and his B.S. is in chemistry. Biochemistry has been a focus of his research and teaching. He especially loves dealing with patent searches and applications for involving biochemistry.

Dr. Demchick is a scientist with a quarter of a century of research experience in academic, industrial and governmental settings.
If you are considering patent protection for an invention, Dr. Demchick will be glad to discuss the matter with you. There is no charge for an initial discussion.
The following sampling is to give you some sense of the types of ubiquitin related inventions which have received United States patent protection. The patent list is not exhaustive and is certainly not a substitute for a proper patent search . It should be noted that only U.S. Patents are included.
It should be noted that spelling, form and typographical errors in the original patents are preserved here.

Enhanced protein production in higher plants by N-terminal fusion of a ubiquitin or a cucumber mosaic virus coat protein peptide (United States Patent 7,087,811)
Ubiquitin conjugation assays (United States Patent 7,022,493)
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents (United States Patent 6,979,551)
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents (United States Patent 6,919,184)
57316 and 33338, human ubiquitin carboxyl terminal hydrolases and uses therefor (United States Patent 6,911,335)
Methods for identifying compounds that inhibit ubiquitin-mediated proteolysis of i.kappa.b (United States Patent 6,905,836)
68999, a human ubiquitin carboxyl-terminal hydrolase family member and uses therefor (United States Patent 6,900,044)
Modified ubiquitin regulatory system (United States Patent 6,878,818)
Component of von Hippel-Lindau tumor suppressor complex and SCF ubiquitin ligase (United States Patent 6,858,709)
Ubiquitin ligase (United States Patent 6,750,057)
Human ubiquitin-conjugating enzyme homologs (United States Patent 6,750,027)
Components of ubiquitin ligase complexes, and uses related thereto (United States Patent 6,747,128)
Ubiquitin ligase assay (United States Patent 6,740,495)
Ubiquitin ligase assay (United States Patent 6,737,244)
Ubiquitin ligases as therapeutic targets (United States Patent 6,720,181)
Biochemical assay to monitor the ubiquitin ligase activities of cullins (United States Patent 6,713,267)
Human E3.alpha. ubiquitin ligase family (United States Patent 6,706,505)
Expression vectors containing hybrid ubiquitin promoters (United States Patent 6,667,174)
Ubiquitin fusion-based vaccine system (United States Patent 6,660,271)
Human skeletal muscle-specific ubiquitin-conjugating enzyme (United States Patent 6,562,947)
Rice ubiquitin-derived promoters (United States Patent 6,528,701)
Cyclin-selective ubiquitin carrier polypeptides (United States Patent 6,528,633)
Ubiquitin ligases and uses related thereto (United States Patent 6,503,742)
23413, a novel human ubiquitin protease (United States Patent 6,451,994)
Ubiquitin-lytic peptide gene promoter (United States Patent 6,448,391)
Methods and compositions for modulating ubiquitin dependent proteolysis (United States Patent 6,426,205)
Biochemical assay to monitor the ubiquitin ligase activities of cullins (United States Patent 6,413,725)
Ubiquitin-like conjugating protein (United States Patent 6,365,358)
23484, A novel human ubiquitin protease (United States Patent 6,329,171)
Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase (United States Patent 6,322,982)
Rapid method of proteasome purification using proteins having sequence homology to ubiquitin (United States Patent 6,294,363)
Nucleic acids encoding human ubiquitin-conjugating enzyme homologs (United States Patent 6,277,568)
Antisense modulation of ubiquitin protein ligase expression (United States Patent 6,258,601)
Cyclin-selective ubiquitin carrier polypeptides (United States Patent 6,180,379)
Human ubiquitin-conjugating enzyme (United States Patent 6,172,199)
Isolated nucleic acid molecule encoding human skeletal muscle-specific ubiquitin-conjugating enzyme (United States Patent 6,166,190)
Human ubiquitin-conjugating enzymes (United States Patent 6,146,624)
Ubiquitin conjugating enzymes (United States Patent 6,127,158)
UBCH7-like ubiquitin-conjugating enzyme (United States Patent 6,124,123)
Human E3 ubiquitin protein ligase (United States Patent 6,087,122)
Ubiquitin expression system (United States Patent 6,068,994)
Ubiquitin conjugating enzymes (United States Patent 6,068,982)
Ubiquitin conjugation proteins (United States Patent 6,057,112)
Plant ubiquitin promoter system (United States Patent 6,054,574)
Plant ubiquitin promoter system (United States Patent 6,020,190)
Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same (United States Patent 6,018,102)
Human ubiquitin-conjugating enzymes (United States Patent 6,015,702)
Ubiquitin ligases, and uses related thereto (United States Patent 6,001,619)
Human ubiquitin-conjugating enzyme (United States Patent 5,989,883)
Human ubiquitin conjugating enzyme (United States Patent 5,981,699)
Human E3 ubiquitin protein ligase (United States Patent 5,976,849)
Ubiquitin conjugating enzymes 8 and 9 (United States Patent 5,968,797)
Ubiquitin conjugating enzymes (United States Patent 5,968,761)
Ubiquitin-like conjugating protein (United States Patent 5,968,747)
Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same (United States Patent 5,955,573)
DNA encoding ubiquitin conjugating enzymes (United States Patent 5,952,481)
UBC7-like ubiquitin-conjugating enzyme (United States Patent 5,952,181)
Ubiquitin conjugating enzymes 7, 8 and 9 (United States Patent 5,945,321)
Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase (United States Patent 5,932,422)
Ubiquitin conjugation proteins (United States Patent 5,922,318)
UBC7-like ubiquitin-conjugating enzyme (United States Patent 5,863,779)
Ubiquitin conjugating enzyme (E2) fusion proteins (United States Patent 5,851,791)
Ubiquitin conjugating enzymes 7,8 and 9 (United States Patent 5,849,286)
UBCH7-like ubiquitin-conjugating enzyme (United States Patent 5,847,094)
Human ubiquitin-conjugating enzyme (United States Patent 5,840,866)
Ubiquitin conjugation proteins (United States Patent 5,817,494)
Ubiquitin fusion protein system for protein production in plants (United States Patent 5,773,705)
Ubiquitin conjugating enzymes having transcriptional repressor activity (United States Patent 5,770,720)
Synthesis of peptides as cloned ubiquitin extensions (United States Patent 5,763,225)
Ubiquitin conjugating enzymes (United States Patent 5,744,343)
Assay and reagents for detecting inhibitors of ubiquitin-dependent degradation of cell cycle regulatory proteins (United States Patent 5,726,025)
Preparation of recombinant ubiquitin cross-reactive protein (UCRP) with improved bioactivity (United States Patent 5,714,347)
Ubiquitin-specific proteases (United States Patent 5,683,904)
Ubiquitin conjugating enzymes 8 and 9 (United States Patent 5,650,313)
Synthesis of peptides as cloned ubiquitin extensions (United States Patent 5,620,923)
Plant ubiquitin promoter system (United States Patent 5,614,399)
Ubiquitin-based split protein sensor (United States Patent 5,585,245)
Plant ubiquitin promoter system (United States Patent 5,510,474)
Split ubiquitin protein sensor (United States Patent 5,503,977)
Ubiquitin-specific proteases (United States Patent 5,494,818)
Methods and vectors for over-expression of ubiquitin fusion proteins in host cells (United States Patent 5,459,051)
Ubiquitin-specific protease (United States Patent 5,391,490)
Ubiquitin carrier enzyme E2-F1, purification, production, and use (United States Patent 5,384,255)
Ubiquitin-peptide extensions as enzyme substrates (United States Patent 5,366,871)
Nucleic acid encoding ubiquitin-specific proteases (United States Patent 5,212,058)
Methods for in vitro cleavage of ubiquitin fusion proteins (United States Patent 5,196,321)
Purified yeast ubiquitin hydrolase (United States Patent 5,156,968)
Method for producing proteins and polypeptides using ubiquitin fusions (United States Patent 5,132,213)
DNA sequences encoding yeast ubiquitin hydrolase (United States Patent 5,108,919)
Peptides having ubiquitin-like activity (United States Patent 4,215,111)
Enhanced protein production in higher plants by N-terminal fusion of a ubiquitin or a cucumber mosaic virus coat protein peptide (United States Patent 7,087,811)
Ubiquitin conjugation assays (United States Patent 7,022,493)
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents (United States Patent 6,979,551)
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents (United States Patent 6,919,184)
57316 and 33338, human ubiquitin carboxyl terminal hydrolases and uses therefor (United States Patent 6,911,335)
Methods for identifying compounds that inhibit ubiquitin-mediated proteolysis of i.kappa.b (United States Patent 6,905,836)
68999, a human ubiquitin carboxyl-terminal hydrolase family member and uses therefor (United States Patent 6,900,044)
Modified ubiquitin regulatory system (United States Patent 6,878,818)
Component of von Hippel-Lindau tumor suppressor complex and SCF ubiquitin ligase (United States Patent 6,858,709)
Ubiquitin ligase (United States Patent 6,750,057)
Human ubiquitin-conjugating enzyme homologs (United States Patent 6,750,027)
Components of ubiquitin ligase complexes, and uses related thereto (United States Patent 6,747,128)
Ubiquitin ligase assay (United States Patent 6,740,495)
Ubiquitin ligase assay (United States Patent 6,737,244)
Ubiquitin ligases as therapeutic targets (United States Patent 6,720,181)
Biochemical assay to monitor the ubiquitin ligase activities of cullins (United States Patent 6,713,267)
Human E3.alpha. ubiquitin ligase family (United States Patent 6,706,505)
Expression vectors containing hybrid ubiquitin promoters (United States Patent 6,667,174)
Ubiquitin fusion-based vaccine system (United States Patent 6,660,271)
Human skeletal muscle-specific ubiquitin-conjugating enzyme (United States Patent 6,562,947)
Rice ubiquitin-derived promoters (United States Patent 6,528,701)
Cyclin-selective ubiquitin carrier polypeptides (United States Patent 6,528,633)
Ubiquitin ligases and uses related thereto (United States Patent 6,503,742)
23413, a novel human ubiquitin protease (United States Patent 6,451,994)
Ubiquitin-lytic peptide gene promoter (United States Patent 6,448,391)
Methods and compositions for modulating ubiquitin dependent proteolysis (United States Patent 6,426,205)
Biochemical assay to monitor the ubiquitin ligase activities of cullins (United States Patent 6,413,725)
Ubiquitin-like conjugating protein (United States Patent 6,365,358)
23484, A novel human ubiquitin protease (United States Patent 6,329,171)
Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase (United States Patent 6,322,982)
Rapid method of proteasome purification using proteins having sequence homology to ubiquitin (United States Patent 6,294,363)
Nucleic acids encoding human ubiquitin-conjugating enzyme homologs (United States Patent 6,277,568)
Antisense modulation of ubiquitin protein ligase expression (United States Patent 6,258,601)
Cyclin-selective ubiquitin carrier polypeptides (United States Patent 6,180,379)
Human ubiquitin-conjugating enzyme (United States Patent 6,172,199)
Isolated nucleic acid molecule encoding human skeletal muscle-specific ubiquitin-conjugating enzyme (United States Patent 6,166,190)
Human ubiquitin-conjugating enzymes (United States Patent 6,146,624)
Ubiquitin conjugating enzymes (United States Patent 6,127,158)
UBCH7-like ubiquitin-conjugating enzyme (United States Patent 6,124,123)
Human E3 ubiquitin protein ligase (United States Patent 6,087,122)
Ubiquitin expression system (United States Patent 6,068,994)
Ubiquitin conjugating enzymes (United States Patent 6,068,982)
Ubiquitin conjugation proteins (United States Patent 6,057,112)
Plant ubiquitin promoter system (United States Patent 6,054,574)
Plant ubiquitin promoter system (United States Patent 6,020,190)
Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same (United States Patent 6,018,102)
Human ubiquitin-conjugating enzymes (United States Patent 6,015,702)
Ubiquitin ligases, and uses related thereto (United States Patent 6,001,619)
Human ubiquitin-conjugating enzyme (United States Patent 5,989,883)
Human ubiquitin conjugating enzyme (United States Patent 5,981,699)
Human E3 ubiquitin protein ligase (United States Patent 5,976,849)
Ubiquitin conjugating enzymes 8 and 9 (United States Patent 5,968,797)
Ubiquitin conjugating enzymes (United States Patent 5,968,761)
Ubiquitin-like conjugating protein (United States Patent 5,968,747)
Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same (United States Patent 5,955,573)
DNA encoding ubiquitin conjugating enzymes (United States Patent 5,952,481)
UBC7-like ubiquitin-conjugating enzyme (United States Patent 5,952,181)
Ubiquitin conjugating enzymes 7, 8 and 9 (United States Patent 5,945,321)
Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase (United States Patent 5,932,422)
Ubiquitin conjugation proteins (United States Patent 5,922,318)
UBC7-like ubiquitin-conjugating enzyme (United States Patent 5,863,779)
Ubiquitin conjugating enzyme (E2) fusion proteins (United States Patent 5,851,791)
Ubiquitin conjugating enzymes 7,8 and 9 (United States Patent 5,849,286)
UBCH7-like ubiquitin-conjugating enzyme (United States Patent 5,847,094)
Human ubiquitin-conjugating enzyme (United States Patent 5,840,866)
Ubiquitin conjugation proteins (United States Patent 5,817,494)
Ubiquitin fusion protein system for protein production in plants (United States Patent 5,773,705)
Ubiquitin conjugating enzymes having transcriptional repressor activity (United States Patent 5,770,720)
Synthesis of peptides as cloned ubiquitin extensions (United States Patent 5,763,225)
Ubiquitin conjugating enzymes (United States Patent 5,744,343)
Assay and reagents for detecting inhibitors of ubiquitin-dependent degradation of cell cycle regulatory proteins (United States Patent 5,726,025)
Preparation of recombinant ubiquitin cross-reactive protein (UCRP) with improved bioactivity (United States Patent 5,714,347)
Ubiquitin-specific proteases (United States Patent 5,683,904)
Ubiquitin conjugating enzymes 8 and 9 (United States Patent 5,650,313)
Synthesis of peptides as cloned ubiquitin extensions (United States Patent 5,620,923)
Plant ubiquitin promoter system (United States Patent 5,614,399)
Ubiquitin-based split protein sensor (United States Patent 5,585,245)
Plant ubiquitin promoter system (United States Patent 5,510,474)
Split ubiquitin protein sensor (United States Patent 5,503,977)
Ubiquitin-specific proteases (United States Patent 5,494,818)
Methods and vectors for over-expression of ubiquitin fusion proteins in host cells (United States Patent 5,459,051)
Ubiquitin-specific protease (United States Patent 5,391,490)
Ubiquitin carrier enzyme E2-F1, purification, production, and use (United States Patent 5,384,255)
Ubiquitin-peptide extensions as enzyme substrates (United States Patent 5,366,871)
Nucleic acid encoding ubiquitin-specific proteases (United States Patent 5,212,058)
Methods for in vitro cleavage of ubiquitin fusion proteins (United States Patent 5,196,321)
Purified yeast ubiquitin hydrolase (United States Patent 5,156,968)
Method for producing proteins and polypeptides using ubiquitin fusions (United States Patent 5,132,213)
DNA sequences encoding yeast ubiquitin hydrolase (United States Patent 5,108,919)
Peptides having ubiquitin-like activity (United States Patent 4,215,111)
Enhanced protein production in higher plants by N-terminal fusion of a ubiquitin or a cucumber mosaic virus coat protein peptide (United States Patent 7,087,811)
Ubiquitin conjugation assays (United States Patent 7,022,493)
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents (United States Patent 6,979,551)
Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents (United States Patent 6,919,184)
57316 and 33338, human ubiquitin carboxyl terminal hydrolases and uses therefor (United States Patent 6,911,335)
Methods for identifying compounds that inhibit ubiquitin-mediated proteolysis of i.kappa.b (United States Patent 6,905,836)
68999, a human ubiquitin carboxyl-terminal hydrolase family member and uses therefor (United States Patent 6,900,044)
Modified ubiquitin regulatory system (United States Patent 6,878,818)
Component of von Hippel-Lindau tumor suppressor complex and SCF ubiquitin ligase (United States Patent 6,858,709)
Ubiquitin ligase (United States Patent 6,750,057)
Human ubiquitin-conjugating enzyme homologs (United States Patent 6,750,027)
Components of ubiquitin ligase complexes, and uses related thereto (United States Patent 6,747,128)
Ubiquitin ligase assay (United States Patent 6,740,495)
Ubiquitin ligase assay (United States Patent 6,737,244)
Ubiquitin ligases as therapeutic targets (United States Patent 6,720,181)
Biochemical assay to monitor the ubiquitin ligase activities of cullins (United States Patent 6,713,267)
Human E3.alpha. ubiquitin ligase family (United States Patent 6,706,505)
Expression vectors containing hybrid ubiquitin promoters (United States Patent 6,667,174)
Ubiquitin fusion-based vaccine system (United States Patent 6,660,271)
Human skeletal muscle-specific ubiquitin-conjugating enzyme (United States Patent 6,562,947)

Although his recognition as a registered patent agent permits him to represent others in all patent matters before the United States Patent and Trademark Office, Dr. Demchick limits his practice to patent matters involving inventions for which he is confident that his expertise will allow him to serve his client well. He will gladly discuss whether he is comfortable handling cases involving inventions in a particular field. He will err on the side of declining cases if he has uncertainty about his ability to do what is needed in the case. Dr. Demchick does not represent clients in court. However, he refers clients to a patent attorney who does represent others in court, if it appears likely that patent related representation in court is appropriate. Dr. Demchick prepares and files non-provisional (regular) patent applications and provisional patent applications. He prepares and files utility patent applications and design patent applications. He prepares and files U.S. patent applications and international patent applications under the Patent Cooperation Treaty (PCT). He prepares and files applications to enter the U.S. National Phase for inventions for which international patent applications (PCT) were already filed. One of the matters he discusses with each client or potential client is which type of application(s) best meets that client's needs. He usually does a patent search (patentability search) as part of the preparation of a patent application. He discusses the value of patent searching with each inventor before agreeing to prepare a patent application for that inventor.